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With the continuous development of machine learning technology, major e-commerce platforms have launched recommendation systems based on it to serve a large number of customers with different needs more efficiently. Compared with…

Machine Learning · Computer Science 2020-12-14 Yang Yu , Zhenhao Gu , Rong Tao , Jingtian Ge , Kenglun Chang

Decision-making in personalized medicine such as cancer therapy or critical care must often make choices for dosage combinations, i.e., multiple continuous treatments. Existing work for this task has modeled the effect of multiple…

Machine Learning · Computer Science 2023-10-30 Jonas Schweisthal , Dennis Frauen , Valentyn Melnychuk , Stefan Feuerriegel

Opponent modeling is necessary in multi-agent settings where secondary agents with competing goals also adapt their strategies, yet it remains challenging because strategies interact with each other and change. Most previous work focuses on…

Machine Learning · Computer Science 2016-09-20 He He , Jordan Boyd-Graber , Kevin Kwok , Hal Daumé

Manipulate and control of the complex quantum system with high precision are essential for achieving universal fault tolerant quantum computing. For a physical system with restricted control resources, it is a challenge to control the…

Quantum Physics · Physics 2021-01-20 Zheng An , Qi-Kai He , Hai-Jing Song , D. L. Zhou

The prognosis for patients with epithelial ovarian cancer remains dismal despite improvements in survival for other cancers. Treatment involves multiple lines of chemotherapy and becomes increasingly heterogeneous after first-line therapy.…

Machine Learning · Computer Science 2021-10-25 Brian Murphy , Mustafa Nasir-Moin , Grace von Oiste , Viola Chen , Howard A Riina , Douglas Kondziolka , Eric K Oermann

We deploy a combination of reinforcement learning-based approaches and more traditional optimization techniques to identify optimal protocols for population transfer in a multi-level system. We constraint our strategy to the case of fixed…

This work aims to study the generalizability of a pre-developed deep learning (DL) dose prediction model for volumetric modulated arc therapy (VMAT) for prostate cancer and to adapt the model to three different internal treatment planning…

In this paper we design and evaluate a Deep-Reinforcement Learning agent that optimizes routing. Our agent adapts automatically to current traffic conditions and proposes tailored configurations that attempt to minimize the network delay.…

Networking and Internet Architecture · Computer Science 2017-09-22 Giorgio Stampa , Marta Arias , David Sanchez-Charles , Victor Muntes-Mulero , Albert Cabellos

Purpose: Radiation therapy treatment planning is a trial-and-error, often time-consuming process. An optimal dose distribution based on a specific anatomy can be predicted by pre-trained deep learning (DL) models. However, dose…

Medical Physics · Physics 2021-09-15 Jianhui Ma , Dan Nguyen , Ti Bai , Michael Folkerts , Xun Jia , Weiguo Lu , Linghong Zhou , Steve Jiang

We methodologically address the problem of Q-value overestimation in deep reinforcement learning to handle high-dimensional state spaces efficiently. By adapting concepts from information theory, we introduce an intrinsic penalty signal…

Artificial Intelligence · Computer Science 2018-11-21 Felix Leibfried , Jordi Grau-Moya , Haitham Bou-Ammar

The behavior decision-making subsystem is a key component of the autonomous driving system, which reflects the decision-making ability of the vehicle and the driver, and is an important symbol of the high-level intelligence of the vehicle.…

Machine Learning · Computer Science 2024-12-31 Zixiang Wang , Hao Yan , Changsong Wei , Junyu Wang , Minheng Xiao

Measurement and estimation of parameters are essential for science and engineering, where one of the main quests is to find systematic schemes that can achieve high precision. While conventional schemes for quantum parameter estimation…

Quantum Physics · Physics 2021-04-29 Han Xu , Junning Li , Liqiang Liu , Yu Wang , Haidong Yuan , Xin Wang

Many multi-genic systemic diseases such as neurological disorders, inflammatory diseases, and the majority of cancers do not have effective treatments yet. Reinforcement learning powered systems pharmacology is a potentially effective…

Biomolecules · Quantitative Biology 2022-02-25 Ryan K. Tan , Yang Liu , Lei Xie

We consider off-policy evaluation (OPE) in continuous treatment settings, such as personalized dose-finding. In OPE, one aims to estimate the mean outcome under a new treatment decision rule using historical data generated by a different…

Machine Learning · Statistics 2021-11-08 Hengrui Cai , Chengchun Shi , Rui Song , Wenbin Lu

Tailoring treatment for individual patients is crucial yet challenging in order to achieve optimal healthcare outcomes. Recent advances in reinforcement learning offer promising personalized treatment recommendations; however, they rely…

Machine Learning · Computer Science 2023-07-06 Simin Ma , Junghwan Lee , Nicoleta Serban , Shihao Yang

Machine-learning techniques are emerging as a valuable tool in experimental physics, and among them, reinforcement learning offers the potential to control high-dimensional, multistage processes in the presence of fluctuating environments.…

In recent years, deep learning has made remarkable strides, surpassing human capabilities in tasks like strategy games, and it has found applications in complex domains, including protein folding. In the realm of quantum chemistry, machine…

Chemical Physics · Physics 2024-01-09 Rhyan Barrett , Julia Westermayr

In recent years, deep reinforcement learning has emerged as a technique to solve closed-loop flow control problems. Employing simulation-based environments in reinforcement learning enables a priori end-to-end optimization of the control…

Fluid Dynamics · Physics 2024-04-11 Andre Weiner , Janis Geise

Recent years have witnessed significant progresses in deep Reinforcement Learning (RL). Empowered with large scale neural networks, carefully designed architectures, novel training algorithms and massively parallel computing devices,…

Machine Learning · Computer Science 2018-04-23 Chiyuan Zhang , Oriol Vinyals , Remi Munos , Samy Bengio

Clinical decision support must adapt online under safety constraints. We present an online adaptive tool where reinforcement learning provides the policy, a patient digital twin provides the environment, and treatment effect defines the…

Artificial Intelligence · Computer Science 2025-08-26 Xinyu Qin , Ruiheng Yu , Lu Wang