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Scarcity of health care resources could result in the unavoidable consequence of rationing. For example, ventilators are often limited in supply, especially during public health emergencies or in resource-constrained health care settings,…

Machine Learning · Computer Science 2024-08-23 Yikuan Li , Chengsheng Mao , Kaixuan Huang , Hanyin Wang , Zheng Yu , Mengdi Wang , Yuan Luo

Quantum machine learning has the potential for a transformative impact across industry sectors and in particular in finance. In our work we look at the problem of hedging where deep reinforcement learning offers a powerful framework for…

In fields such as medicine and social sciences, the goal of treatment is often to maintain the outcome of interest within a desirable range rather than to optimize its value. To achieve this, it may be more practical to recommend a…

Methodology · Statistics 2025-02-17 Chan Park , Guanhua Chen , Menggang Yu

Many real-world applications of reinforcement learning (RL) require making decisions in continuous action environments. In particular, determining the optimal dose level plays a vital role in developing medical treatment regimes. One…

Machine Learning · Statistics 2023-10-03 Yuhan Li , Wenzhuo Zhou , Ruoqing Zhu

Owe to the recent advancements in Artificial Intelligence especially deep learning, many data-driven decision support systems have been implemented to facilitate medical doctors in delivering personalized care. We focus on the deep…

Machine Learning · Computer Science 2019-07-24 Siqi Liu , Kee Yuan Ngiam , Mengling Feng

We consider a multicast scheme recently proposed for a wireless downlink in [1]. It was shown earlier that power control can significantly improve its performance. However for this system, obtaining optimal power control is intractable…

Networking and Internet Architecture · Computer Science 2019-10-25 Ramkumar Raghu , Pratheek Upadhyaya , Mahadesh Panju , Vaneet Aggarwal , Vinod Sharma

Order Picker Routing is a critical issue in Warehouse Operations Management. Due to the complexity of the problem and the need for quick solutions, suboptimal algorithms are frequently employed in practice. However, Reinforcement Learning…

Machine Learning · Computer Science 2024-02-07 George Dunn , Hadi Charkhgard , Ali Eshragh , Sasan Mahmoudinazlou , Elizabeth Stojanovski

Drug repurposing is an effective strategy to identify new uses for existing drugs, providing the quickest possible transition from bench to bedside. Existing methods for drug repurposing that mainly focus on pre-clinical information may…

Applications · Statistics 2021-04-14 Ruoqi Liu , Lai Wei , Ping Zhang

In this work, we present our various contributions to the objective of building a decision support tool for the diagnosis of rare diseases. Our goal is to achieve a state of knowledge where the uncertainty about the patient's disease is…

This paper introduces the OPIAID algorithm, a novel approach for predicting and recommending personalized opioid dosages for individual patients. The algorithm optimizes pain management while minimizing opioid related adverse events (ORADE)…

Pain management in intensive care usually involves complex trade-offs, since both inadequate and excessive treatment can compromise patient safety. Prior work on reinforcement learning for sedation and analgesia has explored how to optimize…

Machine Learning · Computer Science 2026-05-19 Joel Romero-Hernandez , Oscar Camara

In this study we performed a feasibility investigation on implementing a fast and accurate dose calculation based on a deep learning technique. A two dimensional (2D) fluence map was first converted into a three dimensional (3D) volume…

Medical Physics · Physics 2021-02-03 Jiawei Fan , Lei Xing , Peng Dong , Jiazhou Wang , Weigang Hu , Yong Yang

Estimating the impact of continuous treatment variables (e.g., dosage amount) on binary outcomes presents significant challenges in modeling and estimation because many existing approaches make strong assumptions that do not hold for…

Methodology · Statistics 2025-05-08 Muyan Jiang , Yunkai Zhang , Anil Aswani

Deep reinforcement learning enables algorithms to learn complex behavior, deal with continuous action spaces and find good strategies in environments with high dimensional state spaces. With deep reinforcement learning being an active area…

Machine Learning · Computer Science 2018-10-17 Winfried Lötzsch

Traditional methods of surgical decision making heavily rely on human experience and prompt actions, which are variable. A data-driven system generating treatment recommendations based on patient states can be a substantial asset in…

Reinforcement learning systems require good representations to work well. For decades practical success in reinforcement learning was limited to small domains. Deep reinforcement learning systems, on the other hand, are scalable, not…

Machine Learning · Computer Science 2020-03-18 Sina Ghiassian , Banafsheh Rafiee , Yat Long Lo , Adam White

Deep reinforcement learning has successfully been applied for molecular discovery as shown by the Molecule Deep Q-network (MolDQN) algorithm. This algorithm has challenges when applied to optimizing new molecules: training such a model is…

Machine Learning · Computer Science 2023-12-05 Huanyi Qin , Denis Akhiyarov , Sophie Loehle , Kenneth Chiu , Mauricio Araya-Polo

We propose a reinforcement learning (RL)-based system that would automatically prescribe a hypothetical patient medication that may help the patient with their mental health-related speech disfluency, and adjust the medication and the…

Accurate medication dosing holds an important position in the overall patient therapeutic process. Therefore, much research has been conducted to develop optimal administration strategy based on Reinforcement learning (RL). However, Relying…

Machine Learning · Computer Science 2025-10-30 Yooseok Lim , Sujee Lee

Cancer remains a leading cause of death worldwide, necessitating personalized treatment approaches to improve outcomes. Theranostics, combining molecular-level imaging with targeted therapy, offers potential for precision oncology but…

Computational Engineering, Finance, and Science · Computer Science 2025-05-16 Binesh Sadanandan , Vahid Behzadan