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Genetic interactions confer robustness on cells in response to genetic perturbations. This often occurs through molecular buffering mechanisms that can be predicted using, among other features, the degree of coexpression between genes,…

Quantitative Methods · Quantitative Biology 2017-03-14 Alberto Roverato , Robert Castelo

As a crucial problem in statistics is to decide whether additional variables are needed in a regression model. We propose a new multivariate test to investigate the conditional mean independence of Y given X conditioning on some known…

Statistics Theory · Mathematics 2018-05-18 Ze Jin , Xiaohan Yan , David S. Matteson

Two popular approaches for relating correlated measurements of a non-Gaussian response variable to a set of predictors are to fit a marginal model using generalized estimating equations and to fit a generalized linear mixed model by…

Methodology · Statistics 2017-02-23 Jeffrey J. Gory , Peter F. Craigmile , Steven N. MacEachern

In this article, we first extend the construction of random interlacements, introduced by A.S. Sznitman in [arXiv:0704.2560], to the more general setting of transient weighted graphs. We prove the Harris-FKG inequality for this model and…

Probability · Mathematics 2009-07-03 Augusto Teixeira

We consider estimating the shared mean of a sequence of heavy-tailed random variables taking values in a Banach space. In particular, we revisit and extend a simple truncation-based mean estimator first proposed by Catoni and Giulini. While…

Statistics Theory · Mathematics 2025-03-25 Justin Whitehouse , Ben Chugg , Diego Martinez-Taboada , Aaditya Ramdas

This manuscript develops a general purpose inner-product norm for the Kendall \(\tau\) and Spearman's \(\rho\), which operates as an unbiased MLE even in the presence of ties. We derive and prove the strict sub-Gaussianity of the Kemeny…

Methodology · Statistics 2022-08-04 Landon Hurley

We consider graphs that represent pairwise marginal independencies amongst a set of variables (for instance, the zero entries of a covariance matrix for normal data). We characterize the directed acyclic graphs (DAGs) that faithfully…

Artificial Intelligence · Computer Science 2015-08-04 Johannes Textor , Alexander Idelberger , Maciej Liśkiewicz

About forty years ago, in a now--seminal contribution, Rosenbaum & Rubin (1983) introduced a critical characterization of the propensity score as a central quantity for drawing causal inferences in observational study settings. In the…

Methodology · Statistics 2023-02-23 Nima S. Hejazi , Mark J. van der Laan

The Gaussian graphical model (GGM) incorporates an undirected graph to represent the conditional dependence between variables, with the precision matrix encoding partial correlation between pair of variables given the others. To achieve…

Methodology · Statistics 2023-07-03 Yueqi Qian , Xianghong Hu , Can Yang

Many of the classical and recent relations between information and estimation in the presence of Gaussian noise can be viewed as identities between expectations of random quantities. These include the I-MMSE relationship of Guo et al.; the…

Information Theory · Computer Science 2012-05-02 Kartik Venkat , Tsachy Weissman

The ubiquitous ADE classification has induced many proposals of often mysterious correspondences both in mathematics and physics. The mathematics side includes quiver theory and the McKay Correspondence which relates finite group…

High Energy Physics - Theory · Physics 2007-05-23 Yang-Hui He , Jun S. Song

We consider the problem of identifying the parameters of an unknown mixture of two arbitrary $d$-dimensional gaussians from a sequence of independent random samples. Our main results are upper and lower bounds giving a computationally…

Machine Learning · Computer Science 2015-05-19 Moritz Hardt , Eric Price

Quantization techniques have been applied in many challenging finance applications, including pricing claims with path dependence and early exercise features, stochastic optimal control, filtering problems and efficient calibration of large…

Computational Finance · Quantitative Finance 2017-01-11 T. A. McWalter , R. Rudd , J. Kienitz , E. Platen

We introduce the coverage correlation coefficient, a novel nonparametric measure of statistical association designed to quantifies the extent to which two random variables have a joint distribution concentrated on a singular subset with…

Methodology · Statistics 2025-08-18 Xuzhi Yang , Mona Azadkia , Tengyao Wang

A fundamental task in statistical learning is quantifying the joint dependence or association between two continuous random variables. We introduce a novel, fully non-parametric measure that assesses the degree of association between…

The goal of causal mediation analysis, often described within the potential outcomes framework, is to decompose the effect of an exposure on an outcome of interest along different causal pathways. Using the assumption of sequential…

Methodology · Statistics 2021-11-09 Lexi Rene , Antonio R. Linero , Elizabeth Slate

In this note we study a counterpart in predicate logic of the notion of 'logical friendliness', introduced into propositional logic in Makinson (2007). The result is a new consequence relation for predicate languages using first-order…

Logic · Mathematics 2025-01-08 Guillermo Badia , David Clement Makinson

We treat the problem of testing independence between m continuous variables when m can be larger than the available sample size n. We consider three types of test statistics that are constructed as sums or sums of squares of pairwise rank…

Statistics Theory · Mathematics 2016-12-05 Dennis Leung , Mathias Drton

Both latent semantic analysis (LSA) and correspondence analysis (CA) are dimensionality reduction techniques that use singular value decomposition (SVD) for information retrieval. Theoretically, the results of LSA display both the…

Information Retrieval · Computer Science 2023-09-15 Qianqian Qi , David J. Hessen , Peter G. M. van der Heijden

Optimization has two faces, minimization of a loss function or maximization of a gain function. We show that the mean absolute deviations about the mean, d, maximizes a gain function based on the power set of the individuals, and it is…

Methodology · Statistics 2020-03-09 Choulakian Vartan , Abou Samra Ghassan