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Related papers: Calibrating Histopathology Image Classifiers using…

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With the development of deep learning, medical image classification has been significantly improved. However, deep learning requires massive data with labels. While labeling the samples by human experts is expensive and time-consuming,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Jiarun Liu , Ruirui Li , Chuan Sun

We conduct an extensive study on the state of calibration under real-world dataset shift for image classification. Our work provides important insights on the choice of post-hoc and in-training calibration techniques, and yields practical…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Mélanie Roschewitz , Raghav Mehta , Fabio de Sousa Ribeiro , Ben Glocker

Tissue typology annotation in Whole Slide histological images is a complex and tedious, yet necessary task for the development of computational pathology models. We propose to address this problem by applying Open Set Recognition techniques…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Adrian Galdran , Katherine J. Hewitt , Narmin L. Ghaffari , Jakob N. Kather , Gustavo Carneiro , Miguel A. González Ballester

Deep learning-based histopathology image classification is a key technique to help physicians in improving the accuracy and promptness of cancer diagnosis. However, the noisy labels are often inevitable in the complex manual annotation…

Image and Video Processing · Electrical Eng. & Systems 2021-12-08 Chuang Zhu , Wenkai Chen , Ting Peng , Ying Wang , Mulan Jin

This paper concerns the use of objectness measures to improve the calibration performance of Convolutional Neural Networks (CNNs). CNNs have proven to be very good classifiers and generally localize objects well; however, the loss functions…

Computer Vision and Pattern Recognition · Computer Science 2020-12-09 Ujwal Krothapalli , A. Lynn Abbott

In the past years, deep learning has seen an increase in usage in the domain of histopathological applications. However, while these approaches have shown great potential, in high-risk environments deep learning models need to be able to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Hendrik A. Mehrtens , Alexander Kurz , Tabea-Clara Bucher , Titus J. Brinker

Recent advancements in deep learning have proven highly effective in medical image classification, notably within histopathology. However, noisy labels represent a critical challenge in histopathology image classification, where accurate…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Lucas Dedieu , Nicolas Nerrienet , Adrien Nivaggioli , Clara Simmat , Marceau Clavel , Arnaud Gauthier , Stéphane Sockeel , Rémy Peyret

Segmentation of objects of interest is one of the central tasks in medical image analysis, which is indispensable for quantitative analysis. When developing machine-learning based methods for automated segmentation, manual annotations are…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Hang Li , Dong Wei , Shilei Cao , Kai Ma , Liansheng Wang , Yefeng Zheng

Accurate polyp segmentation is of great importance for colorectal cancer diagnosis and treatment. However, due to the high cost of producing accurate mask annotations, existing polyp segmentation methods suffer from severe data shortage and…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Jun Wei , Yiwen Hu , Guanbin Li , Shuguang Cui , S Kevin Zhou , Zhen Li

Introducing training-time augmentations is a key technique to enhance generalization and prepare deep neural networks against test-time corruptions. Inspired by the success of generative diffusion models, we propose a novel approach of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Markus Heinonen , Ba-Hien Tran , Michael Kampffmeyer , Maurizio Filippone

Histopathological characterization of colorectal polyps is an important principle for determining the risk of colorectal cancer and future rates of surveillance for patients. This characterization is time-intensive, requires years of…

Computer Vision and Pattern Recognition · Computer Science 2017-04-14 Bruno Korbar , Andrea M. Olofson , Allen P. Miraflor , Katherine M. Nicka , Matthew A. Suriawinata , Lorenzo Torresani , Arief A. Suriawinata , Saeed Hassanpour

Segmentation of pathological images is essential for accurate disease diagnosis. The quality of manual labels plays a critical role in segmentation accuracy; yet, in practice, the labels between pathologists could be inconsistent, thus…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Li Xiao , Yinhao Li , Luxi Qv , Xinxia Tian , Yijie Peng , S. Kevin Zhou

The classification of histopathological images is of great value in both cancer diagnosis and pathological studies. However, multiple reasons, such as variations caused by magnification factors and class imbalance, make it a challenging…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Yibao Sun , Xingru Huang , Yaqi Wang , Huiyu Zhou , Qianni Zhang

Training neural networks with one-hot target labels often results in overconfidence and overfitting. Label smoothing addresses this issue by perturbing the one-hot target labels by adding a uniform probability vector to create a regularized…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Sachin Chhabra , Hemanth Venkateswara , Baoxin Li

Label smoothing (LS) is a popular regularisation method for training neural networks as it is effective in improving test accuracy and is simple to implement. ``Hard'' one-hot labels are ``smoothed'' by uniformly distributing probability…

Machine Learning · Computer Science 2025-02-21 Guoxuan Xia , Olivier Laurent , Gianni Franchi , Christos-Savvas Bouganis

Current deep learning paradigms largely benefit from the tremendous amount of annotated data. However, the quality of the annotations often varies among labelers. Multi-observer studies have been conducted to study these annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Xiaosong Wang , Ziyue Xu , Dong Yang , Leo Tam , Holger Roth , Daguang Xu

The task of image segmentation is inherently noisy due to ambiguities regarding the exact location of boundaries between anatomical structures. We argue that this information can be extracted from the expert annotations at no extra cost,…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Mobarakol Islam , Ben Glocker

Despite the undeniable progress in visual recognition tasks fueled by deep neural networks, there exists recent evidence showing that these models are poorly calibrated, resulting in over-confident predictions. The standard practices of…

Computer Vision and Pattern Recognition · Computer Science 2024-02-01 Balamurali Murugesan , Bingyuan Liu , Adrian Galdran , Ismail Ben Ayed , Jose Dolz

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

Deep learning models, especially convolutional neural networks, have achieved impressive results in medical image classification. However, these models often produce overconfident predictions, which can undermine their reliability in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Kushan Choudhury , Shubhrodeep Roy , Ankur Chanda , Shubhajit Biswas , Somenath Kuiry