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Related papers: Calibrating Histopathology Image Classifiers using…

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In biomedical imaging, deep learning-based methods are state-of-the-art for every modality (virtual slides, MRI, etc.) In histopathology, these methods can be used to detect certain biomarkers or classify lesions. However, such techniques…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Adrien Nivaggioli , Nicolas Pozin , Rémy Peyret , Stéphane Sockeel , Marie Sockeel , Nicolas Nerrienet , Marceau Clavel , Clara Simmat , Catherine Miquel

Label smoothing (LS) is an arising learning paradigm that uses the positively weighted average of both the hard training labels and uniformly distributed soft labels. It was shown that LS serves as a regularizer for training data with hard…

Machine Learning · Computer Science 2022-06-28 Jiaheng Wei , Hangyu Liu , Tongliang Liu , Gang Niu , Masashi Sugiyama , Yang Liu

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

Developing deep learning models to analyze histology images has been computationally challenging, as the massive size of the images causes excessive strain on all parts of the computing pipeline. This paper proposes a novel deep…

Image and Video Processing · Electrical Eng. & Systems 2021-01-13 Joseph DiPalma , Arief A. Suriawinata , Laura J. Tafe , Lorenzo Torresani , Saeed Hassanpour

The predictive performance of supervised learning algorithms depends on the quality of labels. In a typical label collection process, multiple annotators provide subjective noisy estimates of the "truth" under the influence of their varying…

Machine Learning · Computer Science 2019-06-18 Ryutaro Tanno , Ardavan Saeedi , Swami Sankaranarayanan , Daniel C. Alexander , Nathan Silberman

Deep learning approaches often require huge datasets to achieve good generalization. This complicates its use in tasks like image-based medical diagnosis, where the small training datasets are usually insufficient to learn appropriate data…

Computer Vision and Pattern Recognition · Computer Science 2021-02-12 Roberto Vega , Pouneh Gorji , Zichen Zhang , Xuebin Qin , Abhilash Rakkunedeth Hareendranathan , Jeevesh Kapur , Jacob L. Jaremko , Russell Greiner

Deep neural networks have achieved remarkable success in a wide variety of natural image and medical image computing tasks. However, these achievements indispensably rely on accurately annotated training data. If encountering some…

Image and Video Processing · Electrical Eng. & Systems 2022-05-11 Cheng Xue , Lequan Yu , Pengfei Chen , Qi Dou , Pheng-Ann Heng

Cell detection in histopathology images is of great value in clinical practice. \textit{Convolutional neural networks} (CNNs) have been applied to cell detection to improve the detection accuracy, where cell annotations are required for…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Zipei Zhao , Fengqian Pang , Zhiwen Liu , Chuyang Ye

This paper develops novel conformal prediction methods for classification tasks that can automatically adapt to random label contamination in the calibration sample, leading to more informative prediction sets with stronger coverage…

Methodology · Statistics 2024-02-23 Matteo Sesia , Y. X. Rachel Wang , Xin Tong

Label smoothing is a widely studied regularization technique in machine learning. However, its potential for node classification in graph-structured data, spanning homophilic to heterophilic graphs, remains largely unexplored. We introduce…

Machine Learning · Computer Science 2026-02-02 Jaeseung Heo , Moonjeong Park , Dongwoo Kim

Histopathology images are gigapixel-sized and include features and information at different resolutions. Collecting annotations in histopathology requires highly specialized pathologists, making it expensive and time-consuming.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-16 Jin Li , Deepta Rajan , Chintan Shah , Dinkar Juyal , Shreya Chakraborty , Chandan Akiti , Filip Kos , Janani Iyer , Anand Sampat , Ali Behrooz

In this paper, we address the limitations of the common data annotation and training methods for objective single-label classification tasks. Typically, when annotating such tasks annotators are only asked to provide a single label for each…

Computation and Language · Computer Science 2023-11-10 Ben Wu , Yue Li , Yida Mu , Carolina Scarton , Kalina Bontcheva , Xingyi Song

Automated grading of prostate cancer histopathology images is a challenging task, with one key challenge being the scarcity of annotations down to the level of regions of interest (strong labels), as typically the prostate cancer Gleason…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Eirini Arvaniti , Manfred Claassen

Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced…

High-quality data is necessary for modern machine learning. However, the acquisition of such data is difficult due to noisy and ambiguous annotations of humans. The aggregation of such annotations to determine the label of an image leads to…

Computer Vision and Pattern Recognition · Computer Science 2022-11-07 Lars Schmarje , Vasco Grossmann , Claudius Zelenka , Sabine Dippel , Rainer Kiko , Mariusz Oszust , Matti Pastell , Jenny Stracke , Anna Valros , Nina Volkmann , Reinhard Koch

Training neural networks with high-quality pixel-level annotation in histopathology whole-slide images (WSI) is an expensive process due to gigapixel resolution of WSIs. However, recent advances in self-supervised learning have shown that…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Nohemi Sofia Leon Contreras , Marina D'Amato , Francesco Ciompi , Clement Grisi , Witali Aswolinskiy , Simona Vatrano , Filippo Fraggetta , Iris Nagtegaal

Multiple instance learning (MIL) has enabled substantial progress in computational histopathology, where a large amount of patches from gigapixel whole slide images are aggregated into slide-level predictions. Heatmaps are widely used to…

As current computing capabilities increase, modern machine learning and computer vision system tend to increase in complexity, mostly by means of larger models and advanced optimization strategies. Although often neglected, in many problems…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Adrian Galdran , Miguel A. González Ballester

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Building an accurate computer-aided diagnosis system based on data-driven approaches requires a large amount of high-quality labeled data. In medical imaging analysis, multiple expert annotators often produce subjective estimates about…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Khiem H. Le , Tuan V. Tran , Hieu H. Pham , Hieu T. Nguyen , Tung T. Le , Ha Q. Nguyen