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Related papers: Unsupervised Denoising of Retinal OCT with Diffusi…

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With the great success of diffusion models in image generation, diffusion-based image compression is attracting increasing interests. However, due to the random noise introduced in the diffusion learning, they usually produce…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Zhenyu Du , Yanbo Gao , Shuai Li , Yiyang Li , Hui Yuan , Mao Ye

Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

Optical coherence tomography (OCT) is a label-free, non-invasive 3D imaging tool widely used in both biological research and clinical diagnosis. Current OCT modalities can only visualize specimen tomography without chemical information.…

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Dispersion is a common phenomenon in optics due to the frequency dependence of the refractive index in polychromatic light. This issue, if left untreated in optical coherence tomography (OCT) imaging, leads to signal broadening of the…

Image and Video Processing · Electrical Eng. & Systems 2022-01-03 Shangbang Luo , Guy Holland , Eric Mikula , Samantha Bradford , Reza Khazaeinezhad , James V Jester , Tibor Juhasz

Purpose: To remove retinal shadows from optical coherence tomography (OCT) images of the optic nerve head(ONH). Methods:2328 OCT images acquired through the center of the ONH using a Spectralis OCT machine for both eyes of 13 subjects were…

The evaluation and monitoring of cells health in the human retina is crucial and follow time course of retinal diseases, detect lesions before irreversible visual loss and to evaluate treatment effects. Towards this goal, a major challenge…

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

Human-Computer Interaction · Computer Science 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

Robustness is essential for deep neural networks, especially in security-sensitive applications. To this end, randomized smoothing provides theoretical guarantees for certifying robustness against adversarial perturbations. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Jiachen Lei , Julius Berner , Jiongxiao Wang , Zhongzhu Chen , Zhongjia Ba , Kui Ren , Jun Zhu , Anima Anandkumar

Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Mohammad Rahimzadeh , Mahmoud Reza Mohammadi

Denoising diffusion models represent a recent emerging topic in computer vision, demonstrating remarkable results in the area of generative modeling. A diffusion model is a deep generative model that is based on two stages, a forward…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Florinel-Alin Croitoru , Vlad Hondru , Radu Tudor Ionescu , Mubarak Shah

Diffusion probabilistic models learn to remove noise added during training, generating novel data (e.g., images) from Gaussian noise through sequential denoising. However, conditioning the generative process on corrupted or masked images is…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Sakshi Agarwal , Gabriel Hope , Jimin Heo , Erik B. Sudderth

Segmentation of retinal layers from Optical Coherence Tomography (OCT) volumes is a fundamental problem for any computer aided diagnostic algorithm development. This requires preprocessing steps such as denoising, region of interest…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Karthik Gopinath , Samrudhdhi B Rangrej , Jayanthi Sivaswamy

Diffusion models excel in generating high-quality images. However, current diffusion models struggle to produce reliable images without guidance methods, such as classifier-free guidance (CFG). Are guidance methods truly necessary?…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Donghoon Ahn , Jiwon Kang , Sanghyun Lee , Jaewon Min , Minjae Kim , Wooseok Jang , Hyoungwon Cho , Sayak Paul , SeonHwa Kim , Eunju Cha , Kyong Hwan Jin , Seungryong Kim

Ultrasound imaging is widely used for real-time, noninvasive diagnosis, but speckle and related artifacts reduce image quality and can hinder interpretation. We present a diffusion-based ultrasound despeckling method built on the Image…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Shuoqi Chen , Yujia Wu , Geoffrey P. Luke

Recent studies on learning-based image denoising have achieved promising performance on various noise reduction tasks. Most of these deep denoisers are trained either under the supervision of clean references, or unsupervised on synthetic…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Rui Zhao , Daniel P. K. Lun , Kin-Man Lam

Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can acquire high-resolution volumes of the retinal vasculature and aid the diagnosis of ocular, neurological and cardiac diseases. Segmenting the…

When capturing and storing images, devices inevitably introduce noise. Reducing this noise is a critical task called image denoising. Deep learning has become the de facto method for image denoising, especially with the emergence of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Haoyu Chen , Jinjin Gu , Yihao Liu , Salma Abdel Magid , Chao Dong , Qiong Wang , Hanspeter Pfister , Lei Zhu

Optical coherence tomography (OCT) is a noninvasive technology that enables real-time imaging of tissue microanatomies. The axial resolution of OCT is intrinsically constrained by the spectral bandwidth of the employed light source while…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Kaiyan Li , Jingyuan Yang , Wenxuan Liang , Xingde Li , Chenxi Zhang , Lulu Chen , Chan Wu , Xiao Zhang , Zhiyan Xu , Yuelin Wang , Lihui Meng , Yue Zhang , Youxin Chen , S. Kevin Zhou

The identification and quantification of markers in medical images is critical for diagnosis, prognosis, and disease management. Supervised machine learning enables the detection and exploitation of findings that are known a priori after…