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Related papers: Unsupervised Denoising of Retinal OCT with Diffusi…

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In optical tomography a physical body is illuminated with near-infrared light and the resulting outward photon flux is measured at the object boundary. The goal is to reconstruct internal optical properties of the body, such as absorption…

Numerical Analysis · Mathematics 2016-01-20 Antti Hannukainen , Lauri Harhanen , Nuutti Hyvönen , Helle Majander

Optical Coherence Tomography (OCT) has become an indispensable tool for investigating mesoscopic features in soft matter and fluid mechanics. Its ability to provide high-resolution, non-invasive measurements in both spatial and temporal…

Deep learning has shown impressive results in reducing noise and artifacts in X-ray computed tomography (CT) reconstruction. Self-supervised CT reconstruction methods are especially appealing for real-world applications because they require…

Image and Video Processing · Electrical Eng. & Systems 2026-05-06 Dirk Elias Schut , Adriaan Graas , Robert van Liere , Tristan van Leeuwen

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

Intrinsic optical signal (IOS) imaging of the retina, also termed as optoretinography (ORG), promises a noninvasive method for objective assessment of retinal function. By providing unparalleled capability to differentiate individual layers…

Medical Physics · Physics 2022-02-22 Tae-Hoon Kim , Guangying Ma , Taeyoon Son , Xincheng Yao

Recent advances in diffusion models have spurred research into their application for Reconstruction-based unsupervised anomaly detection. However, these methods may struggle with maintaining structural integrity and recovering the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Farzad Beizaee , Gregory A. Lodygensky , Christian Desrosiers , Jose Dolz

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

While deep learning offers powerful capabilities for scientific research, its application is often hindered by a lack of quantitative reliability. To address this, we introduce a probabilistic denoising framework that simultaneously…

Strongly Correlated Electrons · Physics 2026-05-11 Younsik Kim , Changyoung Kim

Optical coherence tomography angiography (OCTA) is a novel and clinically promising imaging modality to image retinal and sub-retinal vasculature. Based on repeated optical coherence tomography (OCT) scans, intensity changes are observed…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Lennart Husvogt , Stefan B. Ploner , Siyu Chen , Daniel Stromer , Julia Schottenhamml , A. Yasin Alibhai , Eric Moult , Nadia K. Waheed , James G. Fujimoto , Andreas Maier

Low-dose computed tomography (LDCT) became a clear trend in radiology with an aspiration to refrain from delivering excessive X-ray radiation to the patients. The reduction of the radiation dose decreases the risks to the patients but…

Image and Video Processing · Electrical Eng. & Systems 2021-02-05 Elvira Zainulina , Alexey Chernyavskiy , Dmitry V. Dylov

Accurate noise modelling is important for training of deep learning reconstruction algorithms. While noise models are well known for traditional imaging techniques, the noise distribution of a novel sensor may be difficult to determine a…

Machine Learning · Computer Science 2018-07-11 Felix Horger , Tobias Würfl , Vincent Christlein , Andreas Maier

Diffusion models have demonstrated remarkable efficacy in generating high-quality samples. Existing diffusion-based image restoration algorithms exploit pre-trained diffusion models to leverage data priors, yet they still preserve elements…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Hongjie Wu , Linchao He , Mingqin Zhang , Dongdong Chen , Kunming Luo , Mengting Luo , Ji-Zhe Zhou , Hu Chen , Jiancheng Lv

High-numerical-aperture optical coherence tomography (OCT) enables sub-cellular imaging but faces a trade-off between lateral resolution and depth of focus. Computational refocusing can correct defocus in Fourier-domain OCT, yet its…

Optics · Physics 2026-05-22 Yue Zhu , Shuichi Makita , Naoki Fukutake , Yoshiaki Yasuno

Chromatic dispersion is a common problem to degrade the system resolution in optical coherence tomography (OCT). This study is to develop a deep learning network for automated dispersion compensation (ADC-Net) in OCT. The ADC-Net is based…

Convolutional Neural Network models have successfully detected retinal illness from optical coherence tomography (OCT) and fundus images. These CNN models frequently rely on vast amounts of labeled data for training, difficult to obtain,…

Computer Vision and Pattern Recognition · Computer Science 2022-01-28 Sourya Dipta Das , Saikat Dutta , Nisarg A. Shah , Dwarikanath Mahapatra , Zongyuan Ge

All techniques for denoising involve a notion of a true (noise-free) image, and a hypothesis space. The hypothesis space may reconstruct the image directly as a grayscale valued function, or indirectly by its Fourier or wavelet spectrum.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Sajal Chakroborty , Suddhasattwa Das

Optoacoustic tomography image reconstruction has been a problem of interest in recent years. By exploiting the exceptional generative power of the recently proposed diffusion models we consider a scheme which is based on a conditional…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Martin G. Gonzalez , Matias Vera , Leonardo Rey Vega

In optical coherence tomography (OCT), axial resolution and signal-to-noise ratio (SNR) are typically viewed as uncoupled parameters. We show that this is only true for mirror-like surfaces, and that in diffuse scattering samples such as…

Optics · Physics 2022-04-06 Danielle J. Harper , Benjamin J. Vakoc

In this paper, the problem of image super-resolution for Optical Coherence Tomography (OCT) has been addressed. Due to the motion artifacts, OCT imaging is usually done with a low sampling rate and the resulting images are often noisy and…

Image and Video Processing · Electrical Eng. & Systems 2023-06-22 Farnaz Sedighin , Andrzej Cichocki , Hossein Rabbani

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

Quantitative Methods · Quantitative Biology 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang
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