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Modeling the spread of COVID-19 is crucial for informing public health policy. All models for COVID-19 epidemiology rely on parameters describing the dynamics of the infection process. The meanings of epidemiological parameters like R_0,…

Other Quantitative Biology · Quantitative Biology 2020-07-13 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

During an epidemic, such as the COVID-19 pandemic, policy-makers are faced with the decision of implementing effective, yet socioeconomically costly intervention strategies, such as school and workplace closure, physical distancing, etc. In…

Dynamical Systems · Mathematics 2024-07-18 Vasiliki Bitsouni , Nikolaos Gialelis , Vasilis Tsilidis

Epidemic spreading of infectious diseases is ubiquitous and has often considerable impact on public health and economic wealth. The large variability in spatio-temporal patterns of epidemics prohibits simple interventions and demands for a…

Populations and Evolution · Quantitative Biology 2010-11-25 Christel Kamp

Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics. The growing need for realism in addressing complex public health questions is…

Policy responses to COVID-19, particularly those related to non-pharmaceutical interventions, are unprecedented in scale and scope. Epidemiologists are more involved in policy decisions and evidence generation than ever before. However,…

Methodology · Statistics 2021-04-20 Noah A Haber , Emma Clarke-Deelder , Joshua A Salomon , Avi Feller , Elizabeth A Stuart

We develop a spatially dependent generalisation to the Wells-Riley model and its extensions applied to COVID-19, that determines the infection risk due to airborne transmission of viruses. We assume that the concentration of infectious…

Quantitative Methods · Quantitative Biology 2021-05-19 Zechariah Lau , Ian M. Griffiths , Aaron English , Katerina Kaouri

Mathematical modeling has played a central role in understanding how infectious disease transmission manifests in populations. These models have demonstrated the importance of key community-level factors in structuring epidemic risk, and…

Quantitative Methods · Quantitative Biology 2025-06-27 Sudam Surasinghe , Swathi Nachiar Manivannan , Samuel V. Scarpino , Lorin Crawford , C. Brandon Ogbunugafor

A configuration model for epidemic spread, based on a scale-free network, is introduced. We obtain the analytical solutions describing both unstable and stable dynamics of the epidemic spreading, and demonstrate how these regimes can…

Physics and Society · Physics 2020-07-15 Alexander I Nesterov , Pablo Héctor Mata Villafuerte , Gennady P Berman

The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…

Applications · Statistics 2020-08-24 Andres Colubri , Kailash Yadav , Abhishek Jha , Pardis C. Sabeti

During a public health crisis like COVID-19, individuals' adoption of protective behaviors, such as self-isolation and wearing masks, can significantly impact the spread of the disease. In the meanwhile, the spread of the disease can also…

Physics and Society · Physics 2023-10-27 Wenxiang Dong , H. Vicky Zhao

Much traditional statistical modelling assumes that the outcome variables of interest are independent of each other when conditioned on the explanatory variables. This assumption is strongly violated in the case of infectious diseases,…

Populations and Evolution · Quantitative Biology 2019-11-28 Timothy Kinyanjui , Thomas House

This document aims to estimate and describe the effects of the social distancing measures implemented in several countries with the expectancy of controlling the spread of COVID-19. The procedure relies on the classic…

Populations and Evolution · Quantitative Biology 2021-06-28 Gerardo L. Febres

Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it…

Populations and Evolution · Quantitative Biology 2024-01-30 Laura Di Domenico , Eugenio Valdano , Vittoria Colizza

Estimates from infectious disease models have constituted a significant part of the scientific evidence used to inform the response to the COVID-19 pandemic in the UK. These estimates can vary strikingly in their bias and variability.…

Applications · Statistics 2022-10-12 R. E. Moore , C. Rosato , S. Maskell

A mathematical model for estimating the risk of airborne transmission of a respiratory infection such as COVID-19, is presented. The model employs basic concepts from fluid dynamics and incorporates the known scope of factors involved in…

Populations and Evolution · Quantitative Biology 2020-10-28 Rajat Mittal , Charles Meneveau , Wen Wu

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

Social and Information Networks · Computer Science 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov

During the recent pandemic, a rise in COVID-19 cases was followed by a decline in influenza. In the absence of cross-immunity, a potential explanation for the observed pattern is behavioral: non-pharmaceutical interventions (NPIs) designed…

Dynamical Systems · Mathematics 2026-04-20 Leah LeJeune , Omar Saucedo , Lauren M. Childs , Navid Ghaffarzadegan

In this paper, a susceptible-infected-removed (SIR) model has been used to track the evolution of the spread of the COVID-19 virus in four countries of interest. In particular, the epidemic model, that depends on some basic characteristics,…

Populations and Evolution · Quantitative Biology 2020-10-28 Ian Cooper , Argha Mondal , Chris G. Antonopoulos

During the COVID-19 pandemic of 2019/2020, authorities have used temporary ad-hoc policy measures, such as lockdowns and mass quarantines, to slow its transmission. However, the consequences of widespread use of these unprecedented measures…

The current COVID-19 pandemic and subsequent lockdowns have highlighted the close and delicate relationship between a country's public health and economic health. Macroeconomic models that use preexisting epidemic models to calculate the…

Physics and Society · Physics 2020-07-01 Erhan Bayraktar , Asaf Cohen , April Nellis