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Virtual immunohistochemistry (IHC) staining from hematoxylin and eosin (H&E) images can accelerate diagnostics by providing preliminary molecular insight directly from routine sections, reducing the need for repeat sectioning when tissue is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Jillur Rahman Saurav , Thuong Le Hoai Pham , Pritam Mukherjee , Paul Yi , Brent A. Orr , Jacob M. Luber

A deep learning model trained on some labeled data from a certain source domain generally performs poorly on data from different target domains due to domain shifts. Unsupervised domain adaptation methods address this problem by alleviating…

Image and Video Processing · Electrical Eng. & Systems 2019-08-30 Junlin Yang , Nicha C. Dvornek , Fan Zhang , Julius Chapiro , MingDe Lin , James S. Duncan

Recent advances in generative models and adversarial training have led to a flourishing image-to-image (I2I) translation literature. The current I2I translation approaches require training images from the two domains that are either all…

Computer Vision and Pattern Recognition · Computer Science 2019-09-19 Samarth Shukla , Luc Van Gool , Radu Timofte

We propose a novel method that combines CycleGAN and inter-domain losses for semi-supervised end-to-end automatic speech recognition. Inter-domain loss targets the extraction of an intermediate shared representation of speech and text…

Computation and Language · Computer Science 2022-10-24 Chia-Yu Li , Ngoc Thang Vu

Supervised semantic segmentation normally assumes the test data being in a similar data domain as the training data. However, in practice, the domain mismatch between the training and unseen data could lead to a significant performance…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Xianxu Hou , Jingxin Liu , Bolei Xu , Bozhi Liu , Xin Chen , Mohammad Ilyas , Ian Ellis , Jon Garibaldi , Guoping Qiu

Performance of deep learning algorithms decreases drastically if the data distributions of the training and testing sets are different. Due to variations in staining protocols, reagent brands, and habits of technicians, color variation in…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Abhijeet Patil , Mohd. Talha , Aniket Bhatia , Nikhil Cherian Kurian , Sammed Mangale , Sunil Patel , Amit Sethi

In this paper, we aim at solving the multi-domain image-to-image translation problem with a unified model in an unsupervised manner. The most successful work in this area refers to StarGAN, which works well in tasks like face attribute…

Computer Vision and Pattern Recognition · Computer Science 2019-01-17 Xiao Liu , Shengchuan Zhang , Hong Liu , Xin Liu , Cheng Deng , Rongrong Ji

While high-resolution pathology images lend themselves well to `data hungry' deep learning algorithms, obtaining exhaustive annotations on these images is a major challenge. In this paper, we propose a self-supervised CNN approach to…

Computer Vision and Pattern Recognition · Computer Science 2020-08-14 Navid Alemi Koohbanani , Balagopal Unnikrishnan , Syed Ali Khurram , Pavitra Krishnaswamy , Nasir Rajpoot

The ability to automatically learn task specific feature representations has led to a huge success of deep learning methods. When large training data is scarce, such as in medical imaging problems, transfer learning has been very effective.…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 Hariharan Ravishankar , Prasad Sudhakar , Rahul Venkataramani , Sheshadri Thiruvenkadam , Pavan Annangi , Narayanan Babu , Vivek Vaidya

Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Ha-Hieu Pham , Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Ulas Bagci , Min Xu , Trung-Nghia Le , Huy-Hieu Pham

Unpaired image-to-image translation of retinal images can efficiently increase the training dataset for deep-learning-based multi-modal retinal registration methods. Our method integrates a vessel segmentation network into the…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Aline Sindel , Andreas Maier , Vincent Christlein

Scene Parsing is a crucial step to enable autonomous systems to understand and interact with their surroundings. Supervised deep learning methods have made great progress in solving scene parsing problems, however, come at the cost of…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Keng-Chi Liu , Yi-Ting Shen , Jan P. Klopp , Liang-Gee Chen

We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem

Double staining in histopathology, particularly for metaplastic breast cancer, typically employs H&E and P63 dyes. However, P63's tissue damage and high cost necessitate alternative methods. This study introduces xAI-CycleGAN, an advanced…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Tibor Sloboda , Lukáš Hudec , Wanda Benešová

It is commonly recognized that color variations caused by differences in stains is a critical issue for histopathology image analysis. Existing methods adopt color matching, stain separation, stain transfer or the combination of them to…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Hai-Li Ye , Da-Han Wang

Unsupervised domain translation has recently achieved impressive performance with Generative Adversarial Network (GAN) and sufficient (unpaired) training data. However, existing domain translation frameworks form in a disposable way where…

Computer Vision and Pattern Recognition · Computer Science 2019-09-11 Jianxin Lin , Yijun Wang , Tianyu He , Zhibo Chen

Anatomical structures such as blood vessels in contrast-enhanced CT (ceCT) images can be challenging to segment due to the variability in contrast medium diffusion. The combined use of ceCT and contrast-free (CT) CT images can improve the…

Image and Video Processing · Electrical Eng. & Systems 2022-10-05 Giammarco La Barbera , Haithem Boussaid , Francesco Maso , Sabine Sarnacki , Laurence Rouet , Pietro Gori , Isabelle Bloch

Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromatic dyes or fluorescence labels to aid the microscopic…

Medical Physics · Physics 2023-03-07 Bijie Bai , Xilin Yang , Yuzhu Li , Yijie Zhang , Nir Pillar , Aydogan Ozcan

Deep learning has achieved great success in the challenging circuit annotation task by employing Convolutional Neural Networks (CNN) for the segmentation of circuit structures. The deep learning approaches require a large amount of manually…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Yee-Yang Tee , Deruo Cheng , Chye-Soon Chee , Tong Lin , Yiqiong Shi , Bah-Hwee Gwee

Supervised Pix2Pix and unsupervised Cycle-consistency are two modes that dominate the field of medical image-to-image translation. However, neither modes are ideal. The Pix2Pix mode has excellent performance. But it requires paired and well…

Image and Video Processing · Electrical Eng. & Systems 2021-11-12 Lingke Kong , Chenyu Lian , Detian Huang , Zhenjiang Li , Yanle Hu , Qichao Zhou