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Unpaired image-to-image translation has broad applications in art, design, and scientific simulations. One early breakthrough was CycleGAN that emphasizes one-to-one mappings between two unpaired image domains via generative-adversarial…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Dmitrii Torbunov , Yi Huang , Haiwang Yu , Jin Huang , Shinjae Yoo , Meifeng Lin , Brett Viren , Yihui Ren

Histological staining is a vital step used to diagnose various diseases and has been used for more than a century to provide contrast to tissue sections, rendering the tissue constituents visible for microscopic analysis by medical experts.…

Image and Video Processing · Electrical Eng. & Systems 2020-05-08 Yijie Zhang , Kevin de Haan , Yair Rivenson , Jingxi Li , Apostolos Delis , Aydogan Ozcan

Medical image segmentation is routinely performed to isolate regions of interest, such as organs and lesions. Currently, deep learning is the state of the art for automatic segmentation, but is usually limited by the need for supervised…

Image and Video Processing · Electrical Eng. & Systems 2021-02-05 Umaseh Sivanesan , Luis H. Braga , Ranil R. Sonnadara , Kiret Dhindsa

The CycleGAN framework allows for unsupervised image-to-image translation of unpaired data. In a scenario of surgical training on a physical surgical simulator, this method can be used to transform endoscopic images of phantoms into images…

Computer Vision and Pattern Recognition · Computer Science 2021-09-01 Lalith Sharan , Gabriele Romano , Sven Koehler , Halvar Kelm , Matthias Karck , Raffaele De Simone , Sandy Engelhardt

Learning inter-domain mappings from unpaired data can improve performance in structured prediction tasks, such as image segmentation, by reducing the need for paired data. CycleGAN was recently proposed for this problem, but critically…

Machine Learning · Computer Science 2018-06-20 Amjad Almahairi , Sai Rajeswar , Alessandro Sordoni , Philip Bachman , Aaron Courville

The analysis of the tumor environment on digital histopathology slides is becoming key for the understanding of the immune response against cancer, supporting the development of novel immuno-therapies. We introduce here a novel deep…

Image and Video Processing · Electrical Eng. & Systems 2019-06-27 Ansh Kapil , Tobias Wiestler , Simon Lanzmich , Abraham Silva , Keith Steele , Marlon Rebelatto , Guenter Schmidt , Nicolas Brieu

Domain shift in the field of histopathological imaging is a common phenomenon due to the intra- and inter-hospital variability of staining and digitization protocols. The implementation of robust models, capable of creating generalized…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Ilán Carretero , Pablo Meseguer , Rocío del Amor , Valery Naranjo

Domain Adaptation is a technique to address the lack of massive amounts of labeled data in unseen environments. Unsupervised domain adaptation is proposed to adapt a model to new modalities using solely labeled source data and unlabeled…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Thong Vo , Naimul Khan

The original publication Unpaired Image-to-Image Translation using Cycle-Consistent Adversarial Networks served as the inspiration for this implementation project. Researchers developed a novel method for doing image-to-image translations…

Computer Vision and Pattern Recognition · Computer Science 2022-08-16 Sai Pavan Tadem

Unsupervised cross-spectral stereo matching aims at recovering disparity given cross-spectral image pairs without any supervision in the form of ground truth disparity or depth. The estimated depth provides additional information…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Mingyang Liang , Xiaoyang Guo , Hongsheng Li , Xiaogang Wang , You Song

The automated analysis of medical images is currently limited by technical and biological noise and bias. The same source tissue can be represented by vastly different images if the image acquisition or processing protocols vary. For an…

Histopathological evaluation of tissue samples is a key practice in patient diagnosis and drug development, especially in oncology. Historically, Hematoxylin and Eosin (H&E) has been used by pathologists as a gold standard staining.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amal Lahiani , Jacob Gildenblat , Irina Klaman , Shadi Albarqouni , Nassir Navab , Eldad Klaiman

The diagnosis of cancer is mainly performed by visual analysis of the pathologists, through examining the morphology of the tissue slices and the spatial arrangement of the cells. If the microscopic image of a specimen is not stained, it…

Image and Video Processing · Electrical Eng. & Systems 2020-02-06 Pegah Salehi , Abdolah Chalechale

Pathological diagnosis relies on the visual inspection of histologically stained thin tissue specimens, where different types of stains are applied to bring contrast to and highlight various desired histological features. However, the…

Medical Physics · Physics 2022-08-18 Xilin Yang , Bijie Bai , Yijie Zhang , Yuzhu Li , Kevin de Haan , Tairan Liu , Aydogan Ozcan

Deep learning models that are trained on histopathological images obtained from a single lab and/or scanner give poor inference performance on images obtained from another scanner/lab with a different staining protocol. In recent years,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Harshal Nishar , Nikhil Chavanke , Nitin Singhal

Thanks to large-scale labeled training data, deep neural networks (DNNs) have obtained remarkable success in many vision and multimedia tasks. However, because of the presence of domain shift, the learned knowledge of the well-trained DNNs…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Sicheng Zhao , Xuanbai Chen , Xiangyu Yue , Chuang Lin , Pengfei Xu , Ravi Krishna , Jufeng Yang , Guiguang Ding , Alberto L. Sangiovanni-Vincentelli , Kurt Keutzer

Recently, the cycle-consistent generative adversarial networks (CycleGAN) has been widely used for synthesis of multi-domain medical images. The domain-specific nonlinear deformations captured by CycleGAN make the synthesized images…

Computer Vision and Pattern Recognition · Computer Science 2018-08-14 Chengjia Wang , Gillian Macnaught , Giorgos Papanastasiou , Tom MacGillivray , David Newby

CycleGAN provides a framework to train image-to-image translation with unpaired datasets using cycle consistency loss [4]. While results are great in many applications, the pixel level cycle consistency can potentially be problematic and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Tongzhou Wang , Yihan Lin

Annotating histopathological images is a time-consuming andlabor-intensive process, which requires broad-certificated pathologistscarefully examining large-scale whole-slide images from cells to tissues.Recent frontiers of transfer learning…

Computer Vision and Pattern Recognition · Computer Science 2020-08-24 Dou Xu , Chang Cai , Chaowei Fang , Bin Kong , Jihua Zhu , Zhongyu Li

Immunohistochemistry is a valuable diagnostic tool for cancer pathology. However, it requires specialist labs and equipment, is time-intensive, and is difficult to reproduce. Consequently, a long term aim is to provide a digital method of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Christopher D. Walsh , Joanne Edwards , Robert H. Insall