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A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady…

Populations and Evolution · Quantitative Biology 2018-05-16 F. Fatehi Chenar , Y. N. Kyrychko , K. B. Blyuss

We investigate the dynamics of the hepatitis B virus by integrating variable-order calculus and discrete analysis. Specifically, we utilize the Caputo variable-order difference operator in this study. To establish the existence and…

Populations and Evolution · Quantitative Biology 2024-05-27 Meriem Boukhobza , Amar Debbouche , Lingeshwaran Shangerganesh , Delfim F. M. Torres

Discrete and Continuous Dynamics is the first in a series of articles on Network Models for Epidemiology. This project began in the Fall quarter of 2014 in my continuous modeling course. Since then, it has taken off and turned into a series…

Populations and Evolution · Quantitative Biology 2015-11-04 Edward Rusu

We will study a mathematical model of the human immunodeficiency virus (HIV) infection in the presence of combination therapy that includes within-host infectious dynamics. The deterministic model requires us to analyze asymptotic stability…

Populations and Evolution · Quantitative Biology 2017-09-04 Majid Jaberi Douraki

Analysis of the cell population generally provides average information about viral infection in a host whereas the intracellular model captures the individual cellular responses. The primary goal of this study is to comprehensively analyze…

Dynamical Systems · Mathematics 2025-05-20 Rupchand Sutradhar , D C Dalal

In this work, a hepatitis B virus infection dynamics model is proposed including the spatial dependence of viruses. The existence of traveling waves for the proposed model is established through the application of the celebrated Gersgorin…

Dynamical Systems · Mathematics 2024-02-06 Rupchand Sutradhar , D C Dalal

This paper is a survey paper on stochastic epidemic models. A simple stochastic epidemic model is defined and exact and asymptotic model properties (relying on a large community) are presented. The purpose of modelling is illustrated by…

Probability · Mathematics 2009-11-05 Tom Britton

Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). In this paper, the transmission dynamics of hepatitis B is formulated with a mathematical model with considerations of different classes of…

Populations and Evolution · Quantitative Biology 2023-06-01 Blessing O. Emerenini , Simeon C. Inyama

In this paper we analyze a continuous-time epidemic model and its discrete counterpart, where infection spreads both horizontally and vertically. We consider three cases: model with horizontal and imperfect vertical transmissions, model…

Dynamical Systems · Mathematics 2019-06-10 Priyanka Saha , Nandadulal Bairagi

This research gives a thorough examination of an HIV infection model that includes quiescent cells and immune response dynamics in the host. The model, represented by a system of ordinary differential equations, captures the complex…

Populations and Evolution · Quantitative Biology 2025-03-04 Ibrahim Nali , Attila Dénes , Abdessamad Tridane , Xueyong Zhou

This study develops and analyzes a stochastic differential equation (SDE) model for the dynamics of hepatitis B virus (HBV) infection. While deterministic frameworks have yielded important insights into viral behavior, they cannot…

Dynamical Systems · Mathematics 2025-10-03 Abdallah Alsammani

An interesting inference drawn by some Covid-19 epidemiological models is that there exists a proportion of the population who are not susceptible to infection -- even at the start of the current pandemic. This paper introduces a model of…

Quantitative Methods · Quantitative Biology 2020-09-18 Thomas Parr , Anjali Bhat , Peter Zeidman , Aimee Goel , Alexander J. Billig , Rosalyn Moran , Karl J. Friston

The aim of the paper is to describe a model of the development of the Covid-19 contamination of the population of a country or a region. For this purpose a special branching process with two types of individuals is considered. This model is…

Methodology · Statistics 2020-04-03 Nikolay M. Yanev , Vessela K. Stoimenova , Dimitar V. Atanasov

In the Staged Progression (SP) epidemic models, infected individuals are classified into a suitable number of states. The goal of these models is to describe as closely as possible the effect of differences in infectiousness exhibited by…

Dynamical Systems · Mathematics 2024-02-08 Luis Sanz-Lorenzo , Rafael Bravo de la Parra

The abrupt outbreak and transmission of biological diseases has always been a long-time concern of humankind. For long, mathematical modeling has served as a simple and yet efficient tool to investigate, predict, and control spread of…

Populations and Evolution · Quantitative Biology 2020-04-10 Aresh Dadlani , Richard O. Afolabi , Hyoyoung Jung , Khosrow Sohraby , Kiseon Kim

Recently, a long-term model of HIV infection dynamics was developed to describe the entire time course of the disease. It consists of a large system of ODEs with many parameters, and is expensive to simulate. In the current paper, this…

Populations and Evolution · Quantitative Biology 2016-04-20 Tyson Loudon , Stephen Pankavich

This technical report describes the rationale and technical details for the dynamic causal modelling of mitigated epidemiological outcomes based upon a variety of timeseries data. It details the structure of the underlying convolution or…

Populations and Evolution · Quantitative Biology 2020-11-26 Karl J. Friston , Guillaume Flandin , Adeel Razi

In this paper, a mathematical analysis of the global dynamics of a partial differential equation viral infection cellular model is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both…

Analysis of PDEs · Mathematics 2021-11-08 Alexis Nangue , Bruno Nde Tchiffo

Chronic infection with hepatitis B virus (HBV) can lead to formation of abnormal nodular structures within the liver. To address how changes in liver anatomy affect overall virus-host dynamics, we developed within-host ordinary differential…

Other Quantitative Biology · Quantitative Biology 2025-08-01 Keoni Castellano , Omar Saucedo , Stanca M. Ciupe

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann
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