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Multi-sensor data that track system operating behaviors are widely available nowadays from various engineering systems. Measurements from each sensor over time form a curve and can be viewed as functional data. Clustering of these…

Methodology · Statistics 2024-01-08 Zhongnan Jin , Jie Min , Yili Hong , Pang Du , Qingyu Yang

With the rapid advances of microarray technologies, large amounts of high-dimensional gene expression data are being generated, which poses significant computational challenges. A first step towards addressing this challenge is the use of…

Computer Vision and Pattern Recognition · Computer Science 2013-02-14 P. K. Nizar Banu , H. Hannah Inbarani

Clustering is a central approach for unsupervised learning. After clustering is applied, the most fundamental analysis is to quantitatively compare clusterings. Such comparisons are crucial for the evaluation of clustering methods as well…

Machine Learning · Statistics 2017-10-03 Alexander J Gates , Yong-Yeol Ahn

To identify novel dynamic patterns of gene expression, we develop a statistical method to cluster noisy measurements of gene expression collected from multiple replicates at multiple time points, with an unknown number of clusters. We…

Applications · Statistics 2013-12-02 Audrey Qiuyan Fu , Steven Russell , Sarah J. Bray , Simon Tavaré

Segmentation of a colour image composed of different kinds of texture regions can be a hard problem, namely to compute for an exact texture fields and a decision of the optimum number of segmentation areas in an image when it contains…

Artificial Intelligence · Computer Science 2007-05-23 Vitorino Ramos , Fernando Muge

We consider clustering in group decision making where the opinions are given by pairwise comparison matrices. In particular, the k-medoids model is suggested to classify the matrices since it has a linear programming problem formulation…

Optimization and Control · Mathematics 2025-04-17 Kolos Csaba Ágoston , Sándor Bozóki , László Csató

A new method for clustering functional data is proposed via information maximization. The proposed method learns a probabilistic classifier in an unsupervised manner so that mutual information (or squared loss mutual information) between…

Applications · Statistics 2023-06-08 Xinyu Li , Jianjun Xu , Haoyang Cheng

In a standard cluster analysis, such as k-means, in addition to clusters locations and distances between them, it's important to know if they are connected or well separated from each other. The main focus of this paper is discovering the…

Machine Learning · Statistics 2017-05-22 Evgeny Bauman , Konstantin Bauman

This paper introduces a novel model-based clustering approach for clustering time series which present changes in regime. It consists of a mixture of polynomial regressions governed by hidden Markov chains. The underlying hidden process for…

Machine Learning · Statistics 2013-12-30 Faicel Chamroukhi , Allou Samé , Patrice Aknin , Gérard Govaert

Clustering is an unsupervised learning method that constitutes a cornerstone of an intelligent data analysis process. It is used for the exploration of inter-relationships among a collection of patterns, by organizing them into homogeneous…

Machine Learning · Computer Science 2010-04-13 G. Nathiya , S. C. Punitha , M. Punithavalli

As single-cell gene expression data analysis continues to grow, the need for reliable clustering methods has become increasingly important. The prevalence of heuristic means for method choice could lead to inaccurate reports if…

Quantitative Methods · Quantitative Biology 2026-05-19 Owen Visser , Somnath Datta

Many clustering methods, including k-means, require the user to specify the number of clusters as an input parameter. A variety of methods have been devised to choose the number of clusters automatically, but they often rely on strong…

Methodology · Statistics 2017-02-10 Wei Fu , Patrick O. Perry

Genetic data are frequently categorical and have complex dependence structures that are not always well understood. For this reason, clustering and classification based on genetic data, while highly relevant, are challenging statistical…

Methodology · Statistics 2016-06-13 Gabriela Bettella Cybis , Marcio Valk , Silvia Regina Costa Lopes

We propose in this paper an exploratory analysis algorithm for functional data. The method partitions a set of functions into $K$ clusters and represents each cluster by a simple prototype (e.g., piecewise constant). The total number of…

Machine Learning · Statistics 2010-04-06 Georges Hébrail , Bernard Hugueney , Yves Lechevallier , Fabrice Rossi

Connectivity networks have recently become widely used in biology due to increasing amounts of information on the physical and functional links between individual proteins. This connectivity data provides valuable material for expanding our…

Genomics · Quantitative Biology 2013-02-15 O. V. Valba , S. K. Nechaev , O. Vasieva

Gene expression datasets are usually of high dimensionality and therefore require efficient and effective methods for identifying the relative importance of their attributes. Due to the huge size of the search space of the possible…

Machine Learning · Computer Science 2022-06-10 Fernando Jiménez , Gracia Sánchez , José Palma , Luis Miralles-Pechuán , Juan Botía

Traditional machine learning approaches assume that data comes from a single generating mechanism, which may not hold for most real life data. In these cases, the single mechanism assumption can result in suboptimal performance. We…

Machine Learning · Computer Science 2025-01-31 Mehmet Efe Lorasdagi , Ahmet Berker Koc , Ali Taha Koc , Suleyman Serdar Kozat

We introduce a parsimonious model-based framework for clustering time course data. In these applications the computational burden becomes often an issue due to the number of available observations. The measured time series can also be very…

Methodology · Statistics 2015-09-03 Carmela Iorio , Gianluca Frasso , Antonio D'Ambrosio , Roberta Siciliano

Computational analysis methods including machine learning have a significant impact in the fields of genomics and medicine. High-throughput gene expression analysis methods such as microarray technology and RNA sequencing produce enormous…

Genomics · Quantitative Biology 2022-09-28 Nikita Bhandari , Rahee Walambe , Ketan Kotecha , Satyajeet Khare

Spatial transcriptomics measures the expression of thousands of genes in a tissue sample while preserving its spatial structure. This class of technologies has enabled the investigation of the spatial variation of gene expressions and their…

Methodology · Statistics 2025-10-23 Andrea Sottosanti , Davide Risso , Francesco Denti
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