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Related papers: Text Mining Drug/Chemical-Protein Interactions usi…

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Background: Identification of the interactions and regulatory relations between biomolecules play pivotal roles in understanding complex biological systems and the mechanisms underlying diverse biological functions. However, the collection…

Computation and Language · Computer Science 2025-04-24 Gilchan Park , Byung-Jun Yoon , Xihaier Luo , Vanessa López-Marrero , Shinjae Yoo , Shantenu Jha

Recent advances in natural language processing (NLP) have been driven bypretrained language models like BERT, RoBERTa, T5, and GPT. Thesemodels excel at understanding complex texts, but biomedical literature, withits domain-specific…

Computation and Language · Computer Science 2025-07-28 K. Sahit Reddy , N. Ragavenderan , Vasanth K. , Ganesh N. Naik , Vishalakshi Prabhu , Nagaraja G. S

The community of different types of microbes present in a biological niche plays a very important role in functioning of the system. The crosstalk or interactions among the different microbes contributes to the building blocks of such…

Information Retrieval · Computer Science 2023-05-15 Krishanu Das Baksi , Vatsala Pokhrel , Kuntal Kumar Bhusan , Sharmila Mande

Machine based text comprehension has always been a significant research field in natural language processing. Once a full understanding of the text context and semantics is achieved, a deep learning model can be trained to solve a large…

Computation and Language · Computer Science 2020-09-03 Omar Mossad , Amgad Ahmed , Anandharaju Raju , Hari Karthikeyan , Zayed Ahmed

Large language models (LLMs) have demonstrated remarkable performance on single-turn text-to-SQL tasks, but real-world database applications predominantly require multi-turn interactions to handle ambiguous queries, execution errors, and…

Identifying interactions between proteins is important to understand underlying biological processes. Extracting a protein-protein interaction (PPI) from the raw text is often very difficult. Previous supervised learning methods have used…

Quantitative Methods · Quantitative Biology 2018-08-10 Mahtab Ahmed , Jumayel Islam , Muhammad Rifayat Samee , Robert E. Mercer

The Interaction between Drugs and Targets (DTI) in human body plays a crucial role in biomedical science and applications. As millions of papers come out every year in the biomedical domain, automatically discovering DTI knowledge from…

Computation and Language · Computer Science 2021-09-28 Yutai Hou , Yingce Xia , Lijun Wu , Shufang Xie , Yang Fan , Jinhua Zhu , Wanxiang Che , Tao Qin , Tie-Yan Liu

In recent years, protein-text models have gained significant attention for their potential in protein generation and understanding. Current approaches focus on integrating protein-related knowledge into large language models through…

Computation and Language · Computer Science 2025-11-11 Juntong Wu , Zijing Liu , He Cao , Hao Li , Bin Feng , Zishan Shu , Ke Yu , Li Yuan , Yu Li

Extracting relational triples from text is a crucial task for constructing knowledge bases. Recent advancements in joint entity and relation extraction models have demonstrated remarkable F1 scores ($\ge 90\%$) in accurately extracting…

Computation and Language · Computer Science 2023-10-30 Pratik Saini , Samiran Pal , Tapas Nayak , Indrajit Bhattacharya

Peptides play a pivotal role in a wide range of biological activities through participating in up to 40% protein-protein interactions in cellular processes. They also demonstrate remarkable specificity and efficacy, making them promising…

Biomolecules · Quantitative Biology 2024-02-09 Song Yin , Xuenan Mi , Diwakar Shukla

We propose BERTScore, an automatic evaluation metric for text generation. Analogously to common metrics, BERTScore computes a similarity score for each token in the candidate sentence with each token in the reference sentence. However,…

Computation and Language · Computer Science 2020-02-25 Tianyi Zhang , Varsha Kishore , Felix Wu , Kilian Q. Weinberger , Yoav Artzi

We introduce a novel multi-agent collaboration framework designed to enhance the accuracy and robustness of text classification models. Leveraging BERT as the primary classifier, our framework dynamically escalates low-confidence…

Computation and Language · Computer Science 2025-02-27 Hediyeh Baban , Sai A Pidapar , Aashutosh Nema , Sichen Lu

Personalized drug response has received public awareness in recent years. How to combine gene test result and drug sensitivity records is regarded as essential in the real-world implementation. Research articles are good sources to train…

Social and Information Networks · Computer Science 2019-06-20 Shiyin Wang

Language model (LM) pretraining can learn various knowledge from text corpora, helping downstream tasks. However, existing methods such as BERT model a single document, and do not capture dependencies or knowledge that span across…

Computation and Language · Computer Science 2022-03-31 Michihiro Yasunaga , Jure Leskovec , Percy Liang

The rapid growth in literature accumulates diverse and yet comprehensive biomedical knowledge hidden to be mined such as drug interactions. However, it is difficult to extract the heterogeneous knowledge to retrieve or even discover the…

Computation and Language · Computer Science 2021-01-26 Lei Huang , Jiecong Lin , Xiangtao Li , Linqi Song , Ka-Chun Wong

We support scientific writers in determining whether a written sentence is scientific, to which section it belongs, and suggest paraphrasings to improve the sentence. Firstly, we propose a regression model trained on a corpus of scientific…

Computation and Language · Computer Science 2023-06-22 Justin Mücke , Daria Waldow , Luise Metzger , Philipp Schauz , Marcel Hoffman , Nicolas Lell , Ansgar Scherp

We participated in three of the protein-protein interaction subtasks of the Second BioCreative Challenge: classification of abstracts relevant for protein-protein interaction (IAS), discovery of protein pairs (IPS) and text passages…

This paper focuses on using natural language descriptions to enhance predictive models in the chemistry field. Conventionally, chemoinformatics models are trained with extensive structured data manually extracted from the literature. In…

Computation and Language · Computer Science 2023-12-11 Yujie Qian , Zhening Li , Zhengkai Tu , Connor W. Coley , Regina Barzilay

The development of deep neural networks has improved representation learning in various domains, including textual, graph structural, and relational triple representations. This development opened the door to new relation extraction beyond…

Computation and Language · Computer Science 2022-12-22 Masaki Asada

As a fundamental task in computational chemistry, retrosynthesis prediction aims to identify a set of reactants to synthesize a target molecule. Existing template-free approaches only consider the graph structures of the target molecule,…

Computation and Language · Computer Science 2024-01-29 Yifeng Liu , Hanwen Xu , Tangqi Fang , Haocheng Xi , Zixuan Liu , Sheng Zhang , Hoifung Poon , Sheng Wang