English
Related papers

Related papers: Text Mining Drug/Chemical-Protein Interactions usi…

200 papers

Protein-protein interaction extraction is the key precondition of the construction of protein knowledge network, and it is very important for the research in the biomedicine. This paper extracted directional protein-protein interaction from…

Computation and Language · Computer Science 2014-08-25 Peilei Liu , Ting Wang

The prediction modeling of drug-target interactions is crucial to drug discovery and design, which has seen rapid advancements owing to deep learning technologies. Recently developed methods, such as those based on graph neural networks…

Quantitative Methods · Quantitative Biology 2025-11-19 Xinnan Zhang , Jialin Wu , Junyi Xie , Tianlong Chen , Kaixiong Zhou

When patients need to take medicine, particularly taking more than one kind of drug simultaneously, they should be alarmed that there possibly exists drug-drug interaction. Interaction between drugs may have a negative impact on patients or…

Computation and Language · Computer Science 2020-08-31 Siliang Tang , Qi Zhang , Tianpeng Zheng , Mengdi Zhou , Zhan Chen , Lixing Shen , Xiang Ren , Yueting Zhuang , Shiliang Pu , Fei Wu

Text classification problem is a very broad field of study in the field of natural language processing. In short, the text classification problem is to determine which of the previously determined classes the given text belongs to.…

Computation and Language · Computer Science 2021-12-28 D. Emre Taşar , Şükrü Ozan , M. Fatih Akca , Oğuzhan Ölmez , Semih Gülüm , Seçilay Kutal , Ceren Belhan

Toxicity detection of text has been a popular NLP task in the recent years. In SemEval-2021 Task-5 Toxic Spans Detection, the focus is on detecting toxic spans within passages. Most state-of-the-art span detection approaches employ various…

Computation and Language · Computer Science 2021-08-16 Gunjan Chhablani , Abheesht Sharma , Harshit Pandey , Yash Bhartia , Shan Suthaharan

Relation classification is an important NLP task to extract relations between entities. The state-of-the-art methods for relation classification are primarily based on Convolutional or Recurrent Neural Networks. Recently, the pre-trained…

Computation and Language · Computer Science 2019-05-22 Shanchan Wu , Yifan He

Supervised models trained to predict properties from representations have been achieving high accuracy on a variety of tasks. For instance, the BERT family seems to work exceptionally well on the downstream task from NER tagging to the…

Computation and Language · Computer Science 2020-12-22 Tejas Vaidhya , Ayush Kaushal

This paper describes our system for SemEval-2021 Task 5 on Toxic Spans Detection. We developed ensemble models using BERT-based neural architectures and post-processing to combine tokens into spans. We evaluated several pre-trained language…

Computation and Language · Computer Science 2021-08-30 Mikhail Kotyushev , Anna Glazkova , Dmitry Morozov

A biomedical relation statement is commonly expressed in multiple sentences and consists of many concepts, including gene, disease, chemical, and mutation. To automatically extract information from biomedical literature, existing biomedical…

Computation and Language · Computer Science 2021-01-13 Po-Ting Lai , Zhiyong Lu

Intelligently extracting and linking complex scientific information from unstructured text is a challenging endeavor particularly for those inexperienced with natural language processing. Here, we present a simple sequence-to-sequence…

Computation and Language · Computer Science 2022-12-13 Alexander Dunn , John Dagdelen , Nicholas Walker , Sanghoon Lee , Andrew S. Rosen , Gerbrand Ceder , Kristin Persson , Anubhav Jain

This paper studies the performances and behaviors of BERT in ranking tasks. We explore several different ways to leverage the pre-trained BERT and fine-tune it on two ranking tasks: MS MARCO passage reranking and TREC Web Track ad hoc…

Information Retrieval · Computer Science 2019-04-29 Yifan Qiao , Chenyan Xiong , Zhenghao Liu , Zhiyuan Liu

Recent advancements in biological research leverage the integration of molecules, proteins, and natural language to enhance drug discovery. However, current models exhibit several limitations, such as the generation of invalid molecular…

Computation and Language · Computer Science 2024-01-30 Qizhi Pei , Wei Zhang , Jinhua Zhu , Kehan Wu , Kaiyuan Gao , Lijun Wu , Yingce Xia , Rui Yan

Biomedical literature is a rapidly expanding field of science and technology. Classification of biomedical texts is an essential part of biomedicine research, especially in the field of biology. This work proposes the fine-tuned DistilBERT,…

Computation and Language · Computer Science 2024-04-23 Ziqing Guo

This paper presents a novel approach for detecting ChatGPT-generated vs. human-written text using language models. To this end, we first collected and released a pre-processed dataset named OpenGPTText, which consists of rephrased content…

Computation and Language · Computer Science 2023-05-19 Yutian Chen , Hao Kang , Vivian Zhai , Liangze Li , Rita Singh , Bhiksha Raj

End-to-end relation extraction (E2ERE) is an important task in information extraction, more so for biomedicine as scientific literature continues to grow exponentially. E2ERE typically involves identifying entities (or named entity…

Computation and Language · Computer Science 2023-04-05 Xuguang Ai , Ramakanth Kavuluru

Drug discovery remains a slow and expensive process that involves many steps, from detecting the target structure to obtaining approval from the Food and Drug Administration (FDA), and is often riddled with safety concerns. Accurate…

Quantitative Methods · Quantitative Biology 2025-08-22 Ali Vefghi , Zahed Rahmati , Mohammad Akbari

Gene/protein interactions provide critical information for a thorough understanding of cellular processes. Recently, considerable interest and effort has been focused on the construction and analysis of genome-wide gene networks. The large…

Molecular Networks · Quantitative Biology 2022-04-25 Xin Li , Hsinchun Chen , Zan Huang , Hua Su , Jesse D. Martinez

Preventable adverse drug reactions as a result of medical errors present a growing concern in modern medicine. As drug-drug interactions (DDIs) may cause adverse reactions, being able to extracting DDIs from drug labels into…

Computation and Language · Computer Science 2019-05-21 Tung Tran , Ramakanth Kavuluru , Halil Kilicoglu

Background:Typically, proteins perform key biological functions by interacting with each other. As a consequence, predicting which protein pairs interact is a fundamental problem. Experimental methods are slow, expensive, and may be error…

Biomolecules · Quantitative Biology 2022-02-08 Leonardo Martini , Adriano Fazzone , Luca Becchetti

Drug-drug interaction (DDI) is a major cause of morbidity and mortality and a subject of intense scientific interest. Biomedical literature mining can aid DDI research by extracting evidence for large numbers of potential interactions from…

Machine Learning · Statistics 2015-05-19 Artemy Kolchinsky , Anália Lourenço , Heng-Yi Wu , Lang Li , Luis M. Rocha