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Uncertainty quantification of causal effects is crucial for safety-critical applications such as personalized medicine. A powerful approach for this is conformal prediction, which has several practical benefits due to model-agnostic…

Machine Learning · Computer Science 2026-02-04 Maresa Schröder , Dennis Frauen , Jonas Schweisthal , Konstantin Heß , Valentyn Melnychuk , Stefan Feuerriegel

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Abeer Dyoub , Ivan Letteri

One of the key requirements for incorporating machine learning into the drug discovery process is complete reproducibility and traceability of the model building and evaluation process. With this in mind, we have developed an end-to-end…

The treatment effects of medications play a key role in guiding medical prescriptions. They are usually assessed with randomized controlled trials (RCTs), which are expensive. Recently, large-scale electronic health records (EHRs) have…

Machine Learning · Statistics 2019-08-20 Linying Zhang , Yixin Wang , Anna Ostropolets , Jami J. Mulgrave , David M. Blei , George Hripcsak

Perception-related errors comprise most diagnostic mistakes in radiology. To mitigate this problem, radiologists employ personalized and high-dimensional visual search strategies, otherwise known as search patterns. Qualitative descriptions…

We address the problem of sequentially selecting and observing processes from a given set to find the anomalies among them. The decision-maker observes one process at a time and obtains a noisy binary indicator of whether or not the…

Machine Learning · Computer Science 2021-05-14 Geethu Joseph , M. Cenk Gursoy , Pramod K. Varshney

The emergence of large-scale pre-trained vision foundation models has greatly advanced the medical imaging field through the pre-training and fine-tuning paradigm. However, selecting appropriate medical data for downstream fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Anyang Ji , Qingbo Kang , Wei Xu , Changfan Wang , Kang Li , Qicheng Lao

Big longitudinal observational databases present the opportunity to extract new knowledge in a cost effective manner. Unfortunately, the ability of these databases to be used for causal inference is limited due to the passive way in which…

Artificial Intelligence · Computer Science 2016-07-21 Jenna Reps , Zhaoyang Guo , Haoyue Zhu , Uwe Aickelin

Synthetic data provides a promising approach to address data scarcity for training machine learning models; however, adoption without proper quality assessments may introduce artifacts, distortions, and unrealistic features that compromise…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Rucha Deshpande , Tahsin Rahman , Miguel Lago , Adarsh Subbaswamy , Jana G. Delfino , Ghada Zamzmi , Elim Thompson , Aldo Badano , Seyed Kahaki

Anomaly detection is a fundamental task in machine learning and data mining, with significant applications in cybersecurity, industrial fault diagnosis, and clinical disease monitoring. Traditional methods, such as statistical modeling and…

Machine Learning · Computer Science 2025-05-09 Yi Chen

Anomaly detection in complex domains poses significant challenges due to the need for extensive labeled data and the inherently imbalanced nature of anomalous versus benign samples. Graph-based machine learning models have emerged as a…

Machine Learning · Computer Science 2025-07-21 Yifan Wei , Anwar Said , Waseem Abbas , Xenofon Koutsoukos

This paper proposes a statistical framework of using artificial intelligence to improve human decision making. The performance of each human decision maker is benchmarked against that of machine predictions. We replace the diagnoses made by…

Econometrics · Economics 2024-12-10 Kai Feng , Han Hong , Ke Tang , Jingyuan Wang

Medical image segmentation data inherently contain uncertainty. This can stem from both imperfect image quality and variability in labeling preferences on ambiguous pixels, which depend on annotator expertise and the clinical context of the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Jiayuan Zhu , Junde Wu , Cheng Ouyang , Konstantinos Kamnitsas , J. Alison Noble

In recent years, proposed studies on time-series anomaly detection (TAD) report high F1 scores on benchmark TAD datasets, giving the impression of clear improvements in TAD. However, most studies apply a peculiar evaluation protocol called…

Machine Learning · Computer Science 2022-01-05 Siwon Kim , Kukjin Choi , Hyun-Soo Choi , Byunghan Lee , Sungroh Yoon

A common practice in the medical industry is the use of clinical notes, which consist of detailed patient observations. However, electronic health record systems frequently do not contain these observations in a structured format, rendering…

Computation and Language · Computer Science 2023-10-09 Neil Daniel

Longitudinal electronic health record (EHR) data are often left-censored, making diagnosis records incomplete and unreliable for determining disease onset. In contrast, outpatient prescriptions form renewal-based trajectories that provide a…

Machine Learning · Computer Science 2026-03-02 Pavlin G. Poličar , Dalibor Stanimirović , Blaž Zupan

Drug recommendation assists doctors in prescribing personalized medications to patients based on their health conditions. Existing drug recommendation solutions adopt the supervised multi-label classification setup and only work with…

Machine Learning · Computer Science 2022-10-12 Zhenbang Wu , Huaxiu Yao , Zhe Su , David M Liebovitz , Lucas M Glass , James Zou , Chelsea Finn , Jimeng Sun

Clinical predictive algorithms are increasingly being used to form the basis for optimal treatment policies--that is, to enable interventions to be targeted to the patients who will presumably benefit most. Despite taking advantage of…

Applications · Statistics 2020-07-21 Ben J. Marafino , Alejandro Schuler , Vincent X. Liu , Gabriel J. Escobar , Mike Baiocchi

Recent work in machine learning for healthcare has raised concerns about patient privacy and algorithmic fairness. For example, previous work has shown that patient self-reported race can be predicted from medical data that does not…

Machine Learning · Computer Science 2023-11-14 Wei Liao , Joel Voldman

Anomaly detection is vital in many domains, such as finance, healthcare, and cybersecurity. In this paper, we propose a novel deep anomaly detection method for tabular data that leverages Non-Parametric Transformers (NPTs), a model…

Machine Learning · Computer Science 2024-05-03 Hugo Thimonier , Fabrice Popineau , Arpad Rimmel , Bich-Liên Doan
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