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Detecting rare and diverse anomalies in highly imbalanced datasets-such as Advanced Persistent Threats (APTs) in cybersecurity-remains a fundamental challenge for machine learning systems. Active learning offers a promising direction by…

Machine Learning · Computer Science 2026-02-04 Sidahmed Benabderrahmane , Petko Valtchev , James Cheney , Talal Rahwan

Predicting the chemical properties of compounds is crucial in discovering novel materials and drugs with specific desired characteristics. Recent significant advances in machine learning technologies have enabled automatic predictive…

Quantitative Methods · Quantitative Biology 2021-12-10 Yang Liu , Hisashi Kashima

With the proliferation of mobile sensing techniques, huge amounts of time series data are generated and accumulated in various domains, fueling plenty of real-world applications. In this setting, time series anomaly detection is practically…

Machine Learning · Computer Science 2024-07-08 Ronghui Xu , Hao Miao , Senzhang Wang , Philip S. Yu , Jianxin Wang

With the advance of deep learning, much progress has been made in building powerful artificial intelligence (AI) systems for automatic Chest X-ray (CXR) analysis. Most existing AI models are trained to be a binary classifier with the aim of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Xiangyu Peng , Kai Wang , Jianfei Yang , Yingying Zhu , Yang You

This work describes an online processing pipeline designed to identify anomalies in a continuous stream of data collected without external triggers from a particle detector. The processing pipeline begins with a local reconstruction…

High Energy Physics - Experiment · Physics 2023-11-06 Gaia Grosso , Nicolò Lai , Matteo Migliorini , Jacopo Pazzini , Andrea Triossi , Marco Zanetti , Alberto Zucchetta

In this thesis we present the novel semi-supervised network-based algorithm P-Net, which is able to rank and classify patients with respect to a specific phenotype or clinical outcome under study. The peculiar and innovative characteristic…

Machine Learning · Computer Science 2017-02-07 Jessica Gliozzo

Personalizing drug prescriptions in cancer care based on genomic information requires associating genomic markers with treatment effects. This is an unsolved challenge requiring genomic patient data in yet unavailable volumes as well as…

Acceleration processes that occur in astrophysical plasmas produce cosmic rays that are observed on Earth. To study particle acceleration, fully-kinetic particle-in-cell (PIC) simulations are often used as they can unveil the microphysics…

High Energy Astrophysical Phenomena · Physics 2023-08-31 Gabriel Torralba Paz , Artem Bohdan , Jacek Niemiec

With the advancement of treatment modalities in radiation therapy for cancer patients, outcomes have improved, but at the cost of increased treatment plan complexity and planning time. The accurate prediction of dose distributions would…

Medical Physics · Physics 2018-12-03 Dan Nguyen , Troy Long , Xun Jia , Weiguo Lu , Xuejun Gu , Zohaib Iqbal , Steve Jiang

Multistate process data are common in studies of chronic diseases such as cancer. These data are ideal for precision medicine purposes as they can be leveraged to improve more refined health outcomes, compared to standard survival outcomes,…

Methodology · Statistics 2022-11-28 Giorgos Bakoyannis

Feature selection is an important but challenging task in causal inference for obtaining unbiased estimates of causal quantities. Properly selected features in causal inference not only significantly reduce the time required to implement a…

Methodology · Statistics 2025-02-04 Tianyu Yang , Md. Noor-E-Alam

Ultra high-throughput sequencing of transcriptomes (RNA-Seq) has enabled the accurate estimation of gene expression at individual isoform level. However, systematic biases introduced during the sequencing and mapping processes as well as…

Methodology · Statistics 2013-10-02 Hui Jiang , Julia Salzman

Motivation: Microarray data has been recently been shown to be efficacious in distinguishing closely related cell types that often appear in the diagnosis of cancer. It is useful to determine the minimum number of genes needed to do such a…

Biological Physics · Physics 2007-05-23 J. M. Deutsch

An important goal in the field of human-AI interaction is to help users more appropriately trust AI systems' decisions. A situation in which the user may particularly benefit from more appropriate trust is when the AI receives anomalous…

Human-Computer Interaction · Computer Science 2022-04-29 Marissa Radensky , Dustin Burson , Rajya Bhaiya , Daniel S. Weld

In recent years, specific evaluation metrics for time series anomaly detection algorithms have been developed to handle the limitations of the classical precision and recall. However, such metrics are heuristically built as an aggregate of…

Machine Learning · Computer Science 2022-10-13 Alexis Huet , Jose Manuel Navarro , Dario Rossi

State-of-the-art machine learning models require access to significant amount of annotated data in order to achieve the desired level of performance. While unlabelled data can be largely available and even abundant, annotation process can…

Machine Learning · Computer Science 2020-10-15 Rahaf Aljundi , Nikolay Chumerin , Daniel Olmeda Reino

Anomalous pattern detection aims to identify instances where deviation from normalcy is evident, and is widely applicable across domains. Multiple anomalous detection techniques have been proposed in the state of the art. However, there is…

Digitalization in the medical world provides major benefits while making it a target for attackers and thus hard to secure. To deal with network intruders we propose an anomaly detection system on hardware to detect malicious clients in…

Cryptography and Security · Computer Science 2025-06-19 Florian Rokohl , Alexander Lehnert , Marc Reichenbach

We introduce a comprehensive and statistical framework in a model free setting for a complete treatment of localized data corruptions due to severe noise sources, e.g., an occluder in the case of a visual recording. Within this framework,…

Machine Learning · Computer Science 2014-10-02 Huseyin Ozkan , Ozgun S. Pelvan , Suleyman S. Kozat

Anomaly detection or more generally outliers detection is one of the most popular and challenging subject in theoretical and applied machine learning. The main challenge is that in general we have access to very few labeled data or no…

Machine Learning · Computer Science 2023-05-31 Mansour Zoubeirou A Mayaki , Michel Riveill
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