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Informed selection of drug candidates for laboratory experimentation provides an efficient means of identifying suitable anti-cancer treatments. The advancement of artificial intelligence has led to the development of computational models…

Rheumatoid arthritis (RA) is an autoimmune condition caused when patients' immune system mistakenly targets their own tissue. Machine learning (ML) has the potential to identify patterns in patient electronic health records (EHR) to…

Quantitative Methods · Quantitative Biology 2022-10-25 Shengjia Chen , Nikunj Gupta , Woodward B. Galbraith , Valay Shah , Jacopo Cirrone

Adherence can be defined as "the extent to which patients take their medications as prescribed by their healthcare providers"[Osterberg and Blaschke, 2005]. World Health Organization's reports point out that, in developed countries, only…

Machine Learning · Computer Science 2018-11-30 Thomas Janssoone , Clémence Bic , Dorra Kanoun , Pierre Hornus , Pierre Rinder

Comparing outcomes across treatments is essential in medicine and public policy. To do so, researchers typically estimate a set of parameters, possibly counterfactual, with each targeting a different treatment. Treatment-specific means are…

Methodology · Statistics 2025-10-07 Alec McClean , Yiting Li , Sunjae Bae , Mara A. McAdams-DeMarco , Iván Díaz , Wenbo Wu

Inverse optimization has been increasingly used to estimate unknown parameters in an optimization model based on decision data. We show that such a point estimation is insufficient in a prescriptive setting where the estimated parameters…

Optimization and Control · Mathematics 2025-02-11 Bo Lin , Erick Delage , Timothy C. Y. Chan

A key challenge in medical decision making is learning treatment policies for patients with limited observational data. This challenge is particularly evident in personalized healthcare decision-making, where models need to take into…

Machine Learning · Computer Science 2024-03-01 Vrishabh Patil , Kara Hoppe , Yonatan Mintz

Kidney cancer is a global health concern, and accurate assessment of patient frailty is crucial for optimizing surgical outcomes. This paper introduces AI Age Discrepancy, a novel metric derived from machine learning analysis of…

Patient triage plays a crucial role in healthcare, ensuring timely and appropriate care based on the urgency of patient conditions. Traditional triage methods heavily rely on human judgment, which can be subjective and prone to errors.…

Machine Learning · Computer Science 2023-10-11 Pietro Hiram Guzzi , Annamaria De Filippo , Pierangelo Veltri

Medication recommendation is a crucial task in healthcare, especially for patients with complex medical conditions. However, existing methods often struggle to effectively balance the reuse of historical medications with the introduction of…

Artificial Intelligence · Computer Science 2025-07-08 Feiyue Wu , Tianxing Wu , Shenqi Jing

Learning user preferences for products based on their past purchases or reviews is at the cornerstone of modern recommendation engines. One complication in this learning task is that some users are more likely to purchase products or review…

Information Retrieval · Computer Science 2023-03-08 Wanning Chen , Mohsen Bayati

As deep neural networks include a high number of parameters and operations, it can be a challenge to implement these models on devices with limited computational resources. Despite the development of novel pruning methods toward…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Morteza Homayounfar , Mohamad Koohi-Moghadam , Reza Rawassizadeh , Varut Vardhanabhuti

Three-dimensional (3D) freehand ultrasound (US) reconstruction without using any additional external tracking device has seen recent advances with deep neural networks (DNNs). In this paper, we first investigated two identified contributing…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Qi Li , Ziyi Shen , Qian Li , Dean C. Barratt , Thomas Dowrick , Matthew J. Clarkson , Tom Vercauteren , Yipeng Hu

A major concern when dealing with financial time series involving a wide variety ofmarket risk factors is the presence of anomalies. These induce a miscalibration of the models used toquantify and manage risk, resulting in potential…

Statistical Finance · Quantitative Finance 2022-10-26 Stéphane Crépey , Lehdili Noureddine , Nisrine Madhar , Maud Thomas

The use of machine learning to guide clinical decision making has the potential to worsen existing health disparities. Several recent works frame the problem as that of algorithmic fairness, a framework that has attracted considerable…

Machine Learning · Statistics 2021-06-16 Stephen R. Pfohl , Agata Foryciarz , Nigam H. Shah

We describe a statistical method to avoid biased estimation of the content of different particle species. We consider the case when the particle identification information strongly depends on some kinematical variables, whose distributions…

Data Analysis, Statistics and Probability · Physics 2011-06-16 Massimo Casarsa , Pierluigi Catastini , Giovanni Punzi , Luciano Ristori

Improper health insurance payments resulting from fraud and upcoding result in tens of billions of dollars in excess health care costs annually in the United States, motivating machine learning researchers to build anomaly detection models…

Machine Learning · Computer Science 2022-06-17 Jesse B. Crawford , Nicholas Petela

Side effects of prescribed medications are a common occurrence. Electronic healthcare databases present the opportunity to identify new side effects efficiently but currently the methods are limited due to confounding (i.e. when an…

Databases · Computer Science 2016-11-17 Jenna M. Reps , Uwe Aickelin , Jiangang Ma , Yanchun Zhang

With the universal adoption of machine learning in healthcare, the potential for the automation of societal biases to further exacerbate health disparities poses a significant risk. We explore algorithmic fairness from the perspective of…

Machine Learning · Computer Science 2024-04-02 Md Rahat Shahriar Zawad , Peter Washington

Anomaly detection in MRI is of high clinical value in imaging and diagnosis. Unsupervised methods for anomaly detection provide interesting formulations based on reconstruction or latent embedding, offering a way to observe properties…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Ayantika Das , Arun Palla , Keerthi Ram , Mohanasankar Sivaprakasam

Identifying optimal medical treatments to improve survival has long been a critical goal of pharmacoepidemiology. Traditionally, we use an average treatment effect measure to compare outcomes between treatment plans. However, new methods…

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