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Holographic multimode fibre endoscopes have recently shown their ability to unveil and monitor deep brain structures with sub-micrometre resolution, establishing themselves as a minimally-invasive technology with promising applications in…

Multimode fibers (MMFs) have the potential to carry complex images for endoscopy and related applications, but decoding the complex speckle patterns produced by mode-mixing and modal dispersion in MMFs is a serious challenge. Several groups…

Image and Video Processing · Electrical Eng. & Systems 2020-09-02 Changyan Zhu , Eng Aik Chan , You Wang , Weina Peng , Ruixiang Guo , Baile Zhang , Cesare Soci , Yidong Chong

Deep Neural Networks are increasingly used in video frame interpolation tasks such as frame rate changes as well as generating fake face videos. Our project aims to apply recent advances in Deep video interpolation to increase the temporal…

Image and Video Processing · Electrical Eng. & Systems 2020-05-15 Rohit Saha , Abenezer Teklemariam , Ian Hsu , Alan M. Moses

Computational Cannula Microscopy (CCM) is a high-resolution widefield fluorescence imaging approach deep inside tissue, which is minimally invasive. Rather than using conventional lenses, a surgical cannula acts as a lightpipe for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ruipeng Guo , Zhimeng Pan , Andrew Taibi , Jason Shepherd , Rajesh Menon

Modeling of large-scale research facilities is extremely challenging due to complex physical processes and engineering problems. Here, we adopt a data-driven approach to model the longitudinal phase-space diagnostic beamline at the…

Machine Learning · Computer Science 2021-08-11 Jun Zhu , Ye Chen , Frank Brinker , Winfried Decking , Sergey Tomin , Holger Schlarb

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

Computer Vision and Pattern Recognition · Computer Science 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Quantitative phase imaging (QPI) through multi-core fibers (MCFs) has been an emerging in vivo label-free endoscopic imaging modality with minimal invasiveness. However, the computational demands of conventional iterative phase retrieval…

Addition of random phase to the object light is required in computer-generated holograms (CGHs) to widely diffuse the object light and to avoid its concentration on the CGH; however, this addition causes considerable speckle noise in the…

Optics · Physics 2015-06-24 Tomoyoshi Shimobaba , Tomoyoshi Ito

Ultra-thin multimode optical fiber imaging promises next-generation medical endoscopes reaching high image resolution for deep tissues. However, current technology suffers from severe optical distortion, as the fiber's calibration is…

Optics · Physics 2023-10-04 Yijie Zheng , George S. D. Gordon

Deep learning techniques provide a plausible route towards achieving practical imaging through multimode fibers. The results produced by these methods are often influenced by physical factors like temperature, fiber length, external…

Optics · Physics 2024-03-14 Jawaria Maqbool , Syed Talal Hassan , M. Imran Cheema

Imaging through optical multimode fibers (MMFs) has the potential to enable hair-thin endoscopes that reduce the invasiveness of imaging deep inside tissues and organs. Current approaches predominantly require active wavefront shaping and…

Optics · Physics 2021-12-13 Szu-Yu Lee , Vicente J. Parot , Brett E. Bouma , Martin Villiger

For the past forty years, optical fibres have found widespread use in ground-based and space-based instruments. In most applications, these fibres are used in conjunction with conventional optics to transport light. But photonics offers a…

Instrumentation and Methods for Astrophysics · Physics 2016-12-07 Joss Bland-Hawthorn , Seong-Sik Min , Emma Lindley , Sergio Leon-Saval , Simon Ellis , John Lawrence , Martin Roth , Hans-Gerd Lohmannsroben , Sylvain Veilleux

Endomicroscopy is indispensable for minimally invasive diagnostics in clinical practice. For optical keyhole monitoring of surgical interventions, high-resolution fiber endoscopic imaging is considered to be very promising, especially in…

Progress in neuroscience constantly relies on the development of new techniques to investigate the complex dynamics of neuronal networks. An ongoing challenge is to achieve minimally-invasive and high-resolution observations of neuronal…

A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…

Biological Physics · Physics 2017-11-10 Shay Ohayon , Antonio Miguel Caravaca-Aguirre , Rafael Piestun , James J. DiCarlo

Dense pixel-wise image prediction has been advanced by harnessing the capabilities of Fully Convolutional Networks (FCNs). One central issue of FCNs is the limited capacity to handle joint upsampling. To address the problem, we present a…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Huikai Wu , Shuai Zheng , Junge Zhang , Kaiqi Huang

Hologram is an ideal method for naked eye three-dimensional (3D) display, and computer-generated holography (CGH) makes it possible to reconstruct virtual objects. However, the large pixel size of common CGH devices results in shortages in…

Optics · Physics 2019-09-13 Hui Gao , Yuxi Wang , Xuhao Fan , Fenzhang Jiao , Jinsong Xia , Wei Xiong , Minghui Hong

The thin and flexible nature of optical fibres often makes them the ideal technology to view biological processes in-vivo, but current microendoscopic approaches are limited in spatial resolution. Here, we demonstrate a new route to high…

Automatic detection of abnormal cervical cells from Thinprep Cytologic Test (TCT) images is a critical component in the development of intelligent computer-aided diagnostic systems. However, existing algorithms typically fail to effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Jincheng Li , Danyang Dong , Menglin Zheng , Jingbo Zhang , Yueqin Hang , Lichi Zhang , Lili Zhao

Deep neural networks with applications from computer vision and image processing to medical diagnosis are commonly implemented using clock-based processors, where computation speed is limited by the clock frequency and the memory access…

Emerging Technologies · Computer Science 2022-07-06 Farshid Ashtiani , Alexander J. Geers , Firooz Aflatouni