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This paper deals with an initial-boundary value problem for a doubly haptotactic cross-diffusion system arising from the oncolytic virotherapy \begin{equation*} \left\{ \begin{array}{lll} u_t=\Delta u-\nabla \cdot(u\nabla v)+\mu…

Analysis of PDEs · Mathematics 2025-03-06 Yifu Wang , Chi Xu

This work considers a model for oncolytic virotherapy, as given by the reaction-diffusion-taxis system $$ \left\{ \begin{array}{l} u_t = \Delta u - \nabla \cdot (u\nabla v)-\rho uz, \\[1mm] v_t = - (u+w)v, \\[1mm] w_t = D_w \Delta w - w +…

Analysis of PDEs · Mathematics 2020-06-11 Youshan Tao , Michael Winkler

This paper deals with the oncolytic virotherapy model \begin{equation}\begin{split} \begin{cases} &u_t = \Delta u - \nabla \cdot (u\nabla v)-uz +\mu u(1-u),& \\[2ex] &v_t = - (u+w)v,& \\[2ex] &w_t = D_w \Delta w - w + uz,& \\[2ex] &z_t =…

Analysis of PDEs · Mathematics 2020-05-21 Chen Zhen

In this paper, we study the following the coupled chemotaxis--haptotaxis model with remodeling of non-diffusible attractant $$ \left\{\begin{array}{ll} u_t = \Delta u-\chi\nabla\cdot(u\nabla v)- \xi\nabla\cdot(u\nabla w)+\mu u(1- u-w),…

Analysis of PDEs · Mathematics 2017-11-29 Jiashan Zheng

We present a mathematical model describing oncolytic virotherapy treatment of a tumour that proliferates according to a Gompertz growth function. We present local stability analysis and bifurcation plots for relevant model parameters to…

Dynamical Systems · Mathematics 2021-09-30 Adrianne L. Jenner , Peter S. Kim , Federico Frascoli

This paper is concerned with a quasilinear chemotaxis model with indirect signal production, $u_t = \nabla\cdot(D(u)\nabla u - S(u)\nabla v)$, $v_t = \Delta v - v + w$ and $w_t = \Delta w - w + u$, posed on a bounded smooth domain…

Analysis of PDEs · Mathematics 2026-01-06 Xuan Mao , Yuxiang Li

The current series of three papers is concerned with the asymptotic dynamics in the following chemotaxis model $$\partial_tu=\Delta u-\chi\nabla(u\nabla v)+u(a(x,t)-ub(x,t))\ ,\ 0=\Delta v-\lambda v+\mu u \ \ (1)$$where $\chi, \lambda, \mu$…

Analysis of PDEs · Mathematics 2018-04-10 Rachidi B. Salako , Wenxian Shen

This paper deals with the fully parabolic chemotaxis-convection model with sensitivity functions for tumor angiogenesis, \begin{align*} \begin{cases} u_t=\Delta u-\nabla \cdot (u\chi_1(v)\nabla v) +\nabla \cdot (u\chi_2(w)\nabla w), &x \in…

Analysis of PDEs · Mathematics 2023-04-25 Yutaro Chiyo , Masaaki Mizukami

We show global existence and boundedness of classical solutions to a virus infection model with chemotaxis in bounded smooth domains of arbitrary dimension and for any sufficiently regular nonnegative initial data and homogeneous Neumann…

Analysis of PDEs · Mathematics 2017-11-06 Bingran Hu , Johannes Lankeit

This paper studies the following system of differential equations modeling tumor angiogenesis in a bounded smooth domain $\Omega \subset \mathbb{R}^N$ ($N=1,2$): $$\label{0} \left\{\begin{array}{ll} p_t=\Delta p-\nabla\cdotp…

Analysis of PDEs · Mathematics 2019-03-27 Peter Y. H. Pang , Yifu Wang

We consider the chemotaxis model \begin{align*} \begin{cases} u_t = \Delta u - \nabla \cdot (u \nabla v), \\ v_t = \Delta v - vw, \\ w_t = -\delta w + u \end{cases} \end{align*} in smooth, bounded domains $\Omega \subset \mathbb R^n$, $n…

Analysis of PDEs · Mathematics 2019-05-14 Mario Fuest

In this study, we consider the following extended attraction chemotaxis system of two species parabolic-parabolic-elliptic type with nonlocal terms \[ \begin{cases} u_t=d_1\Delta u-\chi_1\nabla (u\cdot \nabla…

Analysis of PDEs · Mathematics 2017-05-17 Tahir Bachar Issa , Rachidi Bolaji Salako

We consider the potentially degenerate haptotaxis system \begin{equation*} \left\{ \begin{aligned} u_t &= \nabla \cdot (\mathbb{D} \nabla u + u \nabla \cdot \mathbb{D}) - \chi \nabla \cdot (u\mathbb{D}\nabla w) + \mu u(1-u^{r- 1}), \\ w_t…

Analysis of PDEs · Mathematics 2023-01-25 Frederic Heihoff

This paper is concerned with a class of reaction-diffusion system with density-suppressed motility \begin{equation*} \begin{cases} u_{t}=\Delta(\gamma(v) u)+\alpha u F(w), & x \in \Omega, \quad t>0, \\ v_{t}=D \Delta v+u-v, & x \in \Omega,…

Analysis of PDEs · Mathematics 2021-02-17 Wenbin Lyu , Zhi-An Wang

This paper studies the asymptotic behavior of solutions of the parabolic-parabolic chemotaxis model with logistic-type sources in heterogeneous bounded domains: \begin{equation*} \label{u-v-eq00} \begin{cases} u_t=\Delta u-\chi\nabla\cdot…

Analysis of PDEs · Mathematics 2026-04-14 Tahir Bachar Issa

In present paper, we consider a chemotaxis consumption system with density-signal governed sensitivity and logistic source: $u_t=\Delta u-\nabla\cdot(\frac{S(u)}{v}\nabla v)+ru-\mu u^2$, $v_t=\Delta v-uv$ in a smooth bounded domain…

Analysis of PDEs · Mathematics 2018-06-27 Mengyao Ding , Xiangdong Zhao

We develop and analyze a mathematical model of oncolytic virotherapy in the treatment of melanoma. We begin with a special, local case of the model, in which we consider the dynamics of the tumour cells in the presence of an oncolytic virus…

Dynamical Systems · Mathematics 2023-09-07 Tedi Ramaj , Xingfu Zou

In this paper, we consider the following parabolic-parabolic-elliptic system } \begin{align*} \left\{\aligned & u_t=\Delta u-\nabla\cdot(u\nabla v)+\xi\nabla\cdot(u\nabla w)+au-\mu u^{\alpha}, && x\in\Omega, t>0,\\ & v_t=\Delta…

Analysis of PDEs · Mathematics 2024-05-28 Fengxiang Zhao , Jiashan Zheng , Kaiqiang Li

Oncolytic virotherapy, utilizing genetically modified viruses to combat cancer and trigger anti-cancer immune responses, has garnered significant attention in recent years. In our previous work arXiv:2305.12386, we developed a stochastic…

Populations and Evolution · Quantitative Biology 2026-04-23 David Morselli , Marcello E. Delitala , Adrianne L. Jenner , Federico Frascoli

We study, in Part I of this series, boundedness and global existence of positive classical solutions to a parabolic-elliptic chemotaxis system with signal-dependent sensitivity and a logistic-type source on a bounded smooth domain…

Analysis of PDEs · Mathematics 2025-12-18 Le Chen , Ian Ruau , Wenxian Shen
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