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A promising technique of discovering disease biomarkers is to measure the relative protein abundance in multiple biofluid samples through liquid chromatography with tandem mass spectrometry (LC-MS/MS) based quantitative proteomics. The key…
This paper introduces HPNet, a novel deep-learning approach for segmenting a 3D shape represented as a point cloud into primitive patches. The key to deep primitive segmentation is learning a feature representation that can separate points…
Cancer is one of the most life-threatening diseases worldwide, and head and neck (H&N) cancer is a prevalent type with hundreds of thousands of new cases recorded each year. Clinicians use medical imaging modalities such as computed…
Computer aided pathological analysis has been the gold standard for tumor diagnosis, however domain shift is a significant problem in histopathology. It may be caused by variability in anatomical structures, tissue preparation, and imaging…
Accurate segmentation of skin lesions in dermatoscopic images is crucial for the early diagnosis of skin cancer and improving the survival rate of patients. However, it is still a challenging task due to the irregularity of lesion areas,…
Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…
The recent surge in performance for image analysis of digitised pathology slides can largely be attributed to the advances in deep learning. Deep models can be used to initially localise various structures in the tissue and hence facilitate…
Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…
Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…
We present a publicly available multimodal dataset for head and neck cancer research, comprising 1123 annotated Positron Emission Tomography/Computed Tomography (PET/CT) studies from patients with histologically confirmed disease, acquired…
Skin cancer is one of the most common cancers in the United States. As technological advancements are made, algorithmic diagnosis of skin lesions is becoming more important. In this paper, we develop algorithms for segmenting the actual…
Digital pathology has seen the advent of a wealth of foundational models (FM), yet to date their performance on cell phenotyping has not been benchmarked in a unified manner. We therefore propose PhenoBench: A comprehensive benchmark for…
Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…
Efficient and precise classification of histological cell nuclei is of utmost importance due to its potential applications in the field of medical image analysis. It would facilitate the medical practitioners to better understand and…
Histopathology images are crucial to the study of complex diseases such as cancer. The histologic characteristics of nuclei play a key role in disease diagnosis, prognosis and analysis. In this work, we propose a sparse Convolutional…
Melanoma is a malignant tumor that originates from skin cell lesions. Accurate and efficient segmentation of skin lesions is essential for quantitative analysis but remains a challenge due to blurred lesion boundaries, gradual color…
Nucleus segmentation is an important task in medical image analysis. However, machine learning models cannot perform well because there are large amount of clusters of crowded nuclei. To handle this problem, existing approaches typically…
Nucleus detection and classification (NDC) in histopathology analysis is a fundamental task that underpins a wide range of high-level pathology applications. However, existing methods heavily rely on labor-intensive nucleus-level…
Accurate classification of brain tumors from MRI scans is critical for effective treatment planning. This study presents a Hybrid Quantum Convolutional Neural Network (HQCNN) that integrates quantum feature-encoding circuits with depth-wise…
An unsupervised data-driven nuclei segmentation method for histology images, called CBM, is proposed in this work. CBM consists of three modules applied in a block-wise manner: 1) data-driven color transform for energy compaction and…