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In computational pathology, nuclear instance segmentation is a fundamental task with many downstream clinical applications. With the advent of deep learning, many approaches, including convolutional neural networks (CNNs) and vision…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Amirreza Mahbod , Ramona Woitek , Jeanne Shen

The grade of clear cell renal cell carcinoma (ccRCC) is a critical prognostic factor, making ccRCC nuclei grading a crucial task in RCC pathology analysis. Computer-aided nuclei grading aims to improve pathologists' work efficiency while…

Image and Video Processing · Electrical Eng. & Systems 2021-06-22 Zeyu Gao , Jiangbo Shi , Xianli Zhang , Yang Li , Haichuan Zhang , Jialun Wu , Chunbao Wang , Deyu Meng , Chen Li

The objective of this paper is to provide a baseline for performing multi-modal data classification on a novel open multimodal dataset of hepatocellular carcinoma (HCC), which includes both image data (contrast-enhanced CT and MRI images)…

Semantic segmentation, a crucial task in computer vision, often relies on labor-intensive and costly annotated datasets for training. In response to this challenge, we introduce FuseNet, a dual-stream framework for self-supervised semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Amirhossein Kazerouni , Sanaz Karimijafarbigloo , Reza Azad , Yury Velichko , Ulas Bagci , Dorit Merhof

Medical image processing usually requires a model trained with carefully crafted datasets due to unique image characteristics and domain-specific challenges, especially in pathology. Primitive detection and segmentation in digitized tissue…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Abu Bakor Hayat Arnob , Xiangxue Wang , Yiping Jiao , Xiao Gan , Wenlong Ming , Jun Xu

The detection of nuclei and cells in histology images is of great value in both clinical practice and pathological studies. However, multiple reasons such as morphological variations of nuclei or cells make it a challenging task where…

Computer Vision and Pattern Recognition · Computer Science 2021-06-28 Yibao Sun , Xingru Huang , Huiyu Zhou , Qianni Zhang

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Cell instance segmentation in cytology images has significant importance for biology analysis and cancer screening, while remains challenging due to 1) the extensive overlapping translucent cell clusters that cause the ambiguous boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Hao Jiang , Rushan Zhang , Yanning Zhou , Yumeng Wang , Hao Chen

In this paper, we introduce a conceptually simple network for generating discriminative tissue-level segmentation masks for the purpose of breast cancer diagnosis. Our method efficiently segments different types of tissues in breast biopsy…

Computer Vision and Pattern Recognition · Computer Science 2018-06-06 Sachin Mehta , Ezgi Mercan , Jamen Bartlett , Donald Weave , Joann G. Elmore , Linda Shapiro

Accurate segmentation of thalamic nuclei from magnetic resonance images is important due to the distinct roles of these nuclei in overall brain function and to their differential involvement in neurological and psychiatric disorders.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Anqi Feng , Zhangxing Bian , Samuel W. Remedios , Savannah P. Hays , Blake E. Dewey , Alexa Colinco , Jiachen Zhuo , Dan Benjamini , Jerry L. Prince

Instance segmentation of nuclei and glands in the histology images is an important step in computational pathology workflow for cancer diagnosis, treatment planning and survival analysis. With the advent of modern hardware, the recent…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Esha Sadia Nasir , Arshi Perviaz , Muhammad Moazam Fraz

Panoptic segmentation is a scene parsing task which unifies semantic segmentation and instance segmentation into one single task. However, the current state-of-the-art studies did not take too much concern on inference time. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Chia-Yuan Chang , Shuo-En Chang , Pei-Yung Hsiao , Li-Chen Fu

Separating overlapped nuclei is a major challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on nuclei segmentation; however, their performance on separating overlapped nuclei…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Haotian Wang , Aleksandar Vakanski , Changfa Shi , Min Xian

Breast Cancer is a major cause of death worldwide among women. Hematoxylin and Eosin (H&E) stained breast tissue samples from biopsies are observed under microscopes for the primary diagnosis of breast cancer. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-26 Aditya Golatkar , Deepak Anand , Amit Sethi

This paper explores the segmentation of very small medical objects with significant clinical value. While Convolutional Neural Networks (CNNs), particularly UNet-like models, and recent Transformers have shown substantial progress in image…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Lingjie Kong , Qiaoling Wei , Chengming Xu , Han Chen , Yanwei Fu

Automatic segmentation of head and neck cancer (HNC) tumors and lymph nodes plays a crucial role in the optimization treatment strategy and prognosis analysis. This study aims to employ nnU-Net for automatic segmentation and radiomics for…

Image and Video Processing · Electrical Eng. & Systems 2022-11-21 Hui Xu , Yihao Li , Wei Zhao , Gwenolé Quellec , Lijun Lu , Mathieu Hatt

The nnU-Net framework has played a crucial role in medical image segmentation and has become the gold standard in multitudes of applications targeting different diseases, organs, and modalities. However, so far it has been used primarily in…

Skin cancer classification is a crucial task in medical image analysis, where precise differentiation between malignant and non-malignant lesions is essential for early diagnosis and treatment. In this study, we explore Sequential and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Shubhi Agarwal , Amulya Kumar Mahto

Accurate skin cancer diagnosis is vital for early treatment and improved patient outcomes. Deep learning (DL) models have shown promise in automating skin cancer classification, yet challenges remain due to data scarcity and limited…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Hamzeh Asgharnezhad , Pegah Tabarisaadi , Abbas Khosravi , Roohallah Alizadehsani , U. Rajendra Acharya

Automated segmentation of distinct tumor regions is critical for accurate diagnosis and treatment planning in pediatric brain tumors. This study evaluates the efficacy of the Multi-Planner U-Net (MPUnet) approach in segmenting different…

Image and Video Processing · Electrical Eng. & Systems 2024-01-15 Sumit Pandey , Satyasaran Changdar , Mathias Perslev , Erik B Dam