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Centrifugation is a widespread laboratory technique used to separate mixtures into fractions characterized by a specific size, weight or density. We demonstrate that centrifugation can be also used to separate swimming cells having…

Soft Condensed Matter · Physics 2014-11-07 Claudio Maggi , Alessia Lepore , Jacopo Solari , Alessandro Rizzo , Roberto Di Leonardo

The spread of microbial infections is governed by the self-organization of bacteria on surfaces. Limitations of live imaging techniques make collective behaviors in clinically relevant systems challenging to quantify. Here, novel…

Biological Physics · Physics 2024-07-19 Vincent Hickl , Abid Khan , René M. Rossi , Bruno F. B. Silva , Katharina Maniura-Weber

The rapid adhesion of motile bacteria from dilute suspensions poses a fundamental non-equilibrium problem: hydrodynamic interactions bias bacterial motion near surfaces without generating stable confinement, while electrostatic interactions…

Soft Condensed Matter · Physics 2026-01-13 Dixi Yang , Anheng Wang , Jia Huang , Xiaofeng Zhuo , Chunming Wang , Hajime Tanaka , Jiaxing Yuan

Capturing biological specimens at large scales with sub-micron resolution is crucial for biomedical research, but conventional cameras often can't handle the pixel requirements. While most microscopes use motorized stages to move samples…

Optics · Physics 2025-03-28 Charlie Kersuzan , Aymerick Bazin , Amaury Badon

Run-and-tumble is a common but vital strategy that bacteria employ to explore environment suffused with boundaries, as well as to escape from entrapment. In this study we reveal how this strategy and the resulting dynamical behavior can be…

Soft Condensed Matter · Physics 2025-01-30 Premkumar Leishangthem , Xuan Wang , Junan Chen , Shengqi Yang , Xinliang Xu

Bacteria sense a diverse range of environmental analytes with high sensitivity and temporal resolution. Engineering and synthetic biology approaches enabled harnessing this capability through development of whole-cell biosensors that…

How systems are endowed with migration capacity is a fascinating question with implications ranging from the design of novel active systems to the control of microbial populations. Bacteria, which can be found in a variety of environments,…

Biological Physics · Physics 2017-07-03 Marc Hennes , Julien Tailleur , Gaëlle Charron , Adrian Daerr

Many bacterial species readily develop biofilms that act as a protective matrix against external challenge, e.g. from antimicrobial treatment. Therefore, biofilms are often responsible for persistent and recurring infections. Established…

Controlling and suppressing bacterial accumulation at solid surfaces is essential for preventing biofilm formation and biofouling. Whereas various chemical surface treatments are known to reduce cell accumulation and attachment, the role of…

Biological Physics · Physics 2019-05-29 Rachel Mok , Jörn Dunkel , Vasily Kantsler

The lack of rapid antibiotic susceptibility tests adversely affects the treatment of bacterial infections and contributes to increased prevalence of multidrug resistant bacteria. Here, we describe an all-electrical approach that allows for…

Applied Physics · Physics 2020-05-06 Yichao Yang , Kalpana Gupta , Kamil L. Ekinci

The community of different types of microbes present in a biological niche plays a very important role in functioning of the system. The crosstalk or interactions among the different microbes contributes to the building blocks of such…

Information Retrieval · Computer Science 2023-05-15 Krishanu Das Baksi , Vatsala Pokhrel , Kuntal Kumar Bhusan , Sharmila Mande

One striking feature of bacterial motion is their ability to swim upstream along corners and crevices, by leveraging hydrodynamic interactions. This motion through anatomic ducts or medical devices might be at the origin of serious…

Soft Condensed Matter · Physics 2020-04-07 Nuris Figueroa-Morales , Aramis Rivera , Rodrigo Soto , Anke Lindner , Ernesto Altshuler , Eric Clement

Can topography be used to control bacteria accumulation? We address this question in the model system of smooth-swimming and run-and-tumble \textit{Escherichia coli} swimming near a sinusoidal surface, and show that the accumulation of…

Soft Condensed Matter · Physics 2023-08-08 Benjamín Pérez-Estay , María Luisa Cordero , Néstor Sepúlveda , Rodrigo Soto

We studied the swimming of \textit{Escherichia coli} bacteria in the vicinity of the critical point in a solution of the non-ionic surfactant \chem{C_{12}E_{5}} in buffer solution. In phase contrast microscopy, each swimming cell produces a…

Soft Condensed Matter · Physics 2018-08-07 Nick Koumakis , Clémence Devailly , Wilson C. K. Poon

Linear waste management systems are unsustainable and contribute to environmental degradation, economic inequity, and health disparities. Among the array of environmental challenges stemming from anthropogenic impacts, the management of…

Quantitative Methods · Quantitative Biology 2024-09-12 Jeff Meilander , J. Gregory Caporaso

Real-life bacteria often swim in complex fluids, but our understanding of the interactions between bacteria and complex surroundings is still evolving. In this work, rod-like \textit{Bacillus subtilis} swims in a quasi-2D environment with…

Bacterial biofilm segmentation poses significant challenges due to lack of apparent structure, poor imaging resolution, limited contrast between conterminous cells and high density of cells that overlap. Although there exist bacterial…

Image and Video Processing · Electrical Eng. & Systems 2019-05-08 Jie Wang , Tamal Batabyal , Mingxing Zhang , Ji Zhang , Arslan Aziz , Andreas Gahlmann , Scott T. Acton

Rapid identification of bacteria is essential to prevent the spread of infectious disease, help combat antimicrobial resistance, and improve patient outcomes. Raman optical spectroscopy promises to combine bacterial detection,…

We use the power density spectra obtained by fluctuation-enhanced sensing of bacterial odors (Escherichia coli and Anthrax-surrogate Bacillus subtilis) to generate new, highly distinguishable, types of patterns based on the average slope of…

General Physics · Physics 2012-02-20 Hung-Chih Chang , Laszlo B. Kish , Maria D. King , Chiman Kwan

Developing rapid methods for pathogen detection and growth monitoring at low cell and analyte concentrations is an important goal, which numerous technologies are working towards solving. Rapid biosensors have already made a dramatic impact…