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Solutions of macromolecules can undergo liquid-liquid phase separation to form droplets with ultra-low surface tension. Droplets with such low surface tension wet and spread over common surfaces such as test tubes and microscope slides,…

We study bacterial diffusion in disordered porous media. Interactions with obstacles, at unknown locations, make this problem challenging. We approach it by abstracting the environment to cell states with memoryless transitions. With this,…

Soft Condensed Matter · Physics 2023-12-29 Henry H. Mattingly

We study the assembly of colloids in a two phase water-water system that provides an environment that can sustain bacteria, providing a new structure with rich potential to confine and structure living colloids. The water-water system,…

Soft Condensed Matter · Physics 2014-12-12 Sarah D. Hann , Mark Goulian , Daeyeon Lee , Kathleen J. Stebe

We propose a computational framework to study the growth and spread of bacterial biofilms on interfaces, as well as the action of antibiotics on them. Bacterial membranes are represented by boundaries immersed in a fluid matrix and subject…

Cell Behavior · Quantitative Biology 2022-01-11 Ana Carpio , Rafael Gonzalez-Albaladejo

Active propulsion, as performed by bacteria and Janus particles, in combination with hydrodynamic interaction results in the accumulation of bacteria at a flat wall. However, in microfluidic devices with cylindrical pillars of sufficiently…

Biological Physics · Physics 2024-04-15 Theresa Jakuszeit , Ottavio A. Croze

Bacterial heterogeneity is pivotal for adaptation to diverse environments, posing significant challenges in microbial diagnostics and therapeutic interventions. Recent advancements in high-resolution optical microscopy have revolutionized…

Biological Physics · Physics 2025-01-06 Dohyeon Lee , Hyun-Seung Lee , Moosung Lee , Minhee Kang , Geon Kim , Tae Yeul Kim , Nam Yong Lee , YongKeun Park

Dynamics of a bubble impacting and sliding a tilted surface has been investigated through experimental and computational methods. \textcolor{blue}{Specifically, shear stress generated on the wall has been calculated and compared with…

Fluid Dynamics · Physics 2018-10-30 Ehsan Esmaili , Pranav Shukla , Joseph D. Eifert , Sunghwan Jung

Bacterial resistance to antibiotic treatment is a huge concern: introduction of any new antibiotic is shortly followed by the emergence of resistant bacterial isolates in the clinic. This issue is compounded by a severe lack of new…

Cell Behavior · Quantitative Biology 2014-09-16 Lucy Ternent , Rosemary J. Dyson , Anne-Marie Krachler , Sara Jabbari

Bacterial biofilms play a significant role in various fields that impact our daily lives, from detrimental public health hazards to beneficial applications in bioremediation, biodegradation, and wastewater treatment. However,…

We propose a model of antibiotic diffusion through a bacterial biofilm when diffusion and/or absorption barriers develop in the biofilm. The idea of this model is: We deduce details of the diffusion process in a medium in which direct…

Biological Physics · Physics 2020-09-23 Tadeusz Kosztołowicz , Ralf Metzler

The trajectories of microswimmers moving in narrow channels of widths comparable to their sizes are significantly altered when they encounter another microswimmer moving in the opposite direction. The consequence of these encounters is a…

We present a generic mechanism by which reproducing microorganisms, with a diffusivity that depends on the local population density, can form stable patterns. It is known that a decrease of swimming speed with density can promote separation…

Populations and Evolution · Quantitative Biology 2010-07-13 M. E. Cates , D. Marenduzzo , I. Pagonabarraga , J. Tailleur

The behavior of fluid interfaces far from equilibrium plays central roles in nature and in industry. Active swimmers trapped at interfaces can alter transport at fluid boundaries with far reaching implications. Swimmers can become trapped…

Soft Condensed Matter · Physics 2024-02-08 Jiayi Deng , Mehdi Molaei , Nicholas G. Chisholm , Kathleen J. Stebe

Many self-propelled microorganisms are attracted to surfaces. This makes their dynamics in restricted geometries very different from that observed in the bulk. Swimming along walls is beneficial for directing and sorting cells, but may be…

Raman spectroscopy is a promising tool for microbial identification, yet its implementation in microbiology and clinical workflow is still restricted due to the accompanying additional preparation required to focus on microbial signals.…

Quantitative Methods · Quantitative Biology 2026-03-19 Jeong Hee Kim , Jia Dong , Marissa Morales , Loza Tadesse

A hallmark of bacterial populations cultured in vitro is their homogeneity of growth, where the majority of cells display identical growth rate, cell size and content. Recent insights, however, have revealed that even cells growing in…

Quantitative Methods · Quantitative Biology 2022-06-07 Santosh Pandey , Yunsoo Park , Ankita Ankita , Gregory J. Phillips

Antibiotic resistance is a topical problem for both humans and animals and has been the subject of special monitoring for two decades. Several recent studies, including ours, have shown that this phenomenon is accentuated by the transfer of…

Biomolecules · Quantitative Biology 2021-08-16 Mbarga Manga Joseph Arsene

Bacterial populations that colonize a host play important roles in host health, including serving as a reservoir that transmits to other hosts and from which invasive strains emerge, thus emphasizing the importance of understanding rates of…

A new technique for the separation of macromolecules is proposed and investigated. A thin mesh with pores comparable to the radius of gyration of a free chain is used to filter chains according to their length. Without a field it has…

Soft Condensed Matter · Physics 2009-10-28 J. M. Deutsch , Hyoungsoo Yoon

Near-field hydrodynamic interactions between bacteria and no-slip solid surfaces are the main mechanism underlying surface entrapment of bacteria. In this study, we employ a chiral two-body model to simulate bacterial dynamics near the…

Soft Condensed Matter · Physics 2026-02-25 Baopi Liu , Lu Chen , Haiqin Wang