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Mechanical ventilation is a critical life support intervention that delivers controlled air and oxygen to a patient's lungs, assisting or replacing spontaneous breathing. While several data-driven approaches have been proposed to optimize…

Machine Learning · Computer Science 2025-01-10 Joo Seung Lee , Malini Mahendra , Anil Aswani

Building models of human decision-making from observed behaviour is critical to better understand, diagnose and support real-world policies such as clinical care. As established policy learning approaches remain focused on imitation…

Machine Learning · Computer Science 2022-10-03 Alizée Pace , Alex J. Chan , Mihaela van der Schaar

The COVID-19 pandemic has highlighted the importance of supply chains and the role of digital management to react to dynamic changes in the environment. In this work, we focus on developing dynamic inventory ordering policies for a…

Machine Learning · Computer Science 2023-03-23 Julien Siems , Maximilian Schambach , Sebastian Schulze , Johannes S. Otterbach

Decision makers, such as doctors and judges, make crucial decisions such as recommending treatments to patients, and granting bails to defendants on a daily basis. Such decisions typically involve weighting the potential benefits of taking…

Machine Learning · Statistics 2016-11-24 Himabindu Lakkaraju , Cynthia Rudin

Scarcity of health care resources could result in the unavoidable consequence of rationing. For example, ventilators are often limited in supply, especially during public health emergencies or in resource-constrained health care settings,…

Machine Learning · Computer Science 2024-08-23 Yikuan Li , Chengsheng Mao , Kaixuan Huang , Hanyin Wang , Zheng Yu , Mengdi Wang , Yuan Luo

In response to the COVID-19 pandemic, the integration of interpretable machine learning techniques has garnered significant attention, offering transparent and understandable insights crucial for informed clinical decision making. This…

Machine Learning · Computer Science 2024-09-10 Jinzhi Shen , Ke Ma

State-of-the-art clustering algorithms use heuristics to partition the feature space and provide little insight into the rationale for cluster membership, limiting their interpretability. In healthcare applications, the latter poses a…

Machine Learning · Statistics 2018-12-04 Dimitris Bertsimas , Agni Orfanoudaki , Holly Wiberg

We propose an approach for learning optimal tree-based prescription policies directly from data, combining methods for counterfactual estimation from the causal inference literature with recent advances in training globally-optimal decision…

Machine Learning · Computer Science 2020-12-07 Maxime Amram , Jack Dunn , Ying Daisy Zhuo

Markov decision process models and algorithms can be used to identify optimal policies for dispatching ambulances to spatially distributed customers, where the optimal policies indicate the ambulance to dispatch to each customer type in…

Optimization and Control · Mathematics 2023-03-03 Laura A. Albert

Interpretability is crucial for doctors, hospitals, pharmaceutical companies and biotechnology corporations to analyze and make decisions for high stakes problems that involve human health. Tree-based methods have been widely adopted for…

Machine Learning · Computer Science 2024-05-24 Rui Zhang , Rui Xin , Margo Seltzer , Cynthia Rudin

Since the first wave of the COVID-19 pandemic, governments have applied restrictions in order to slow down its spreading. However, creating such policies is hard, especially because the government needs to trade-off the spreading of the…

Machine Learning · Computer Science 2022-05-03 Leonardo Lucio Custode , Giovanni Iacca

Medical Triage is of paramount importance to healthcare systems, allowing for the correct orientation of patients and allocation of the necessary resources to treat them adequately. While reliable decision-tree methods exist to triage…

We consider the problem of learning an optimal prescriptive tree (i.e., an interpretable treatment assignment policy in the form of a binary tree) of moderate depth, from observational data. This problem arises in numerous socially…

Machine Learning · Computer Science 2023-07-25 Nathanael Jo , Sina Aghaei , Andrés Gómez , Phebe Vayanos

Reinforcement learning techniques leveraging deep learning have made tremendous progress in recent years. However, the complexity of neural networks prevents practitioners from understanding their behavior. Decision trees have gained…

Machine Learning · Computer Science 2024-08-22 Daniël Vos , Sicco Verwer

Clinical decision support tools rooted in machine learning and optimization can provide significant value to healthcare providers, including through better management of intensive care units. In particular, it is important that the patient…

Machine Learning · Computer Science 2021-12-20 Fernando Lejarza , Jacob Calvert , Misty M Attwood , Daniel Evans , Qingqing Mao

Data-driven pricing strategies are becoming increasingly common, where customers are offered a personalized price based on features that are predictive of their valuation of a product. It is desirable for this pricing policy to be simple…

Machine Learning · Statistics 2021-06-11 Max Biggs , Wei Sun , Markus Ettl

High-dimensional policies, such as those represented by neural networks, cannot be reasonably interpreted by humans. This lack of interpretability reduces the trust users have in policy behavior, limiting their use to low-impact tasks such…

Machine Learning · Computer Science 2021-09-20 John Mern , Sidhart Krishnan , Anil Yildiz , Kyle Hatch , Mykel J. Kochenderfer

Tree ensembles are very popular machine learning models, known for their effectiveness in supervised classification and regression tasks. Their performance derives from aggregating predictions of multiple decision trees, which are renowned…

Optimization and Control · Mathematics 2025-01-14 Lorenzo Bonasera , Emilio Carrizosa

Decision trees are ubiquitous in machine learning for their ease of use and interpretability. Yet, these models are not typically employed in reinforcement learning as they cannot be updated online via stochastic gradient descent. We…

Machine Learning · Computer Science 2020-06-29 Andrew Silva , Taylor Killian , Ivan Dario Jimenez Rodriguez , Sung-Hyun Son , Matthew Gombolay

Optimal treatment rules can improve health outcomes on average by assigning a treatment associated with the most desirable outcome to each individual. Due to an unknown data generation mechanism, it is appealing to use flexible models to…

Methodology · Statistics 2023-11-21 Lingjie Shen , Gijs Geleijnse , Maurits Kaptein
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