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Large language models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), especially in domains where labeled data is scarce or expensive, such as clinical domain. However, to unlock the clinical knowledge hidden…

Computation and Language · Computer Science 2023-09-18 Sonish Sivarajkumar , Mark Kelley , Alyssa Samolyk-Mazzanti , Shyam Visweswaran , Yanshan Wang

Objective: The generalizability of clinical large language models is usually ignored during the model development process. This study evaluated the generalizability of BERT-based clinical NLP models across different clinical settings…

Computation and Language · Computer Science 2023-03-16 Sicheng Zhou , Nan Wang , Liwei Wang , Ju Sun , Anne Blaes , Hongfang Liu , Rui Zhang

Objective: To develop a natural language processing system that solves both clinical concept extraction and relation extraction in a unified prompt-based machine reading comprehension (MRC) architecture with good generalizability for…

Computation and Language · Computer Science 2023-07-07 Cheng Peng , Xi Yang , Zehao Yu , Jiang Bian , William R. Hogan , Yonghui Wu

Background: Electronic health records (EHRs) are a valuable resource for data-driven medical research. However, the presence of protected health information (PHI) makes EHRs unsuitable to be shared for research purposes. De-identification,…

Computation and Language · Computer Science 2024-04-11 Aleksandar Kovačević , Bojana Bašaragin , Nikola Milošević , Goran Nenadić

Large language models (LLMs) such as GPT-4o and o1 have demonstrated strong performance on clinical natural language processing (NLP) tasks across multiple medical benchmarks. Nonetheless, two high-impact NLP tasks - structured tabular…

Specialised pre-trained language models are becoming more frequent in NLP since they can potentially outperform models trained on generic texts. BioBERT and BioClinicalBERT are two examples of such models that have shown promise in medical…

Neural networks models for NLP are typically implemented without the explicit encoding of language rules and yet they are able to break one performance record after another. This has generated a lot of research interest in interpreting the…

Computation and Language · Computer Science 2019-11-14 Mariya Toneva , Leila Wehbe

Linking clinical narratives to standardized vocabularies and coding systems is a key component of unlocking the information in medical text for analysis. However, many domains of medical concepts lack well-developed terminologies that can…

Computation and Language · Computer Science 2021-03-11 Denis Newman-Griffis , Eric Fosler-Lussier

We investigate the potential benefit of incorporating dictionary information into a neural network architecture for natural language processing. In particular, we make use of this architecture to extract several concepts related to COVID-19…

Computation and Language · Computer Science 2023-09-06 Abul Hasan , Mark Levene , David Weston

Large Language Models (LLMs) have demonstrated remarkable proficiency in automated text annotation within natural language processing. However, their deployment in clinical settings is severely constrained by strict privacy regulations and…

Recruiting patients to participate in clinical trials can be challenging and time-consuming. Usually, participation in a clinical trial is initiated by a healthcare professional and proposed to the patient. Promoting clinical trials…

Computation and Language · Computer Science 2025-03-21 Mathilde Aguiar , Pierre Zweigenbaum , Nona Naderi

Understanding the prevalence, disparities, and symptom variations of Post COVID-19 Condition (PCC) for vulnerable populations is crucial to improving care and addressing intersecting inequities. This study aims to develop a comprehensive…

Computation and Language · Computer Science 2025-02-25 Juan Andres Medina Florez , Shaina Raza , Rashida Lynn , Zahra Shakeri , Brendan T. Smith , Elham Dolatabadi

Misinformation of COVID-19 is prevalent on social media as the pandemic unfolds, and the associated risks are extremely high. Thus, it is critical to detect and combat such misinformation. Recently, deep learning models using natural…

Computation and Language · Computer Science 2021-03-02 Jackie Ayoub , X. Jessie Yang , Feng Zhou

Daily progress notes are common types in the electronic health record (EHR) where healthcare providers document the patient's daily progress and treatment plans. The EHR is designed to document all the care provided to patients, but it also…

Artificial Intelligence · Computer Science 2023-03-15 Yanjun Gao , Dmitriy Dligach , Timothy Miller , Matthew M Churpek , Ozlem Uzuner , Majid Afshar

Smart healthcare has achieved significant progress in recent years. Emerging artificial intelligence (AI) technologies enable various smart applications across various healthcare scenarios. As an essential technology powered by AI, natural…

Computation and Language · Computer Science 2023-03-23 Binggui Zhou , Guanghua Yang , Zheng Shi , Shaodan Ma

This study aims to explore the implementation of Natural Language Processing (NLP) and machine learning (ML) techniques to automate the coding of medical letters with visualised explainability and light-weighted local computer settings.…

Computation and Language · Computer Science 2024-07-19 Jamie Glen , Lifeng Han , Paul Rayson , Goran Nenadic

How can we interpret and retrieve medical evidence to support clinical decisions? Clinical trial reports (CTR) amassed over the years contain indispensable information for the development of personalized medicine. However, it is practically…

Computation and Language · Computer Science 2023-10-31 Maël Jullien , Marco Valentino , Hannah Frost , Paul O'Regan , Donal Landers , André Freitas

This preprint presents a systematic, research-oriented practicum that guides the reader through the entire modern NLP pipeline: from tokenisation and vectorisation to fine-tuning of large language models, retrieval-augmented generation, and…

Computation and Language · Computer Science 2026-05-12 Mullosharaf K. Arabov

Objective The evaluation of natural language processing (NLP) models for clinical text de-identification relies on the availability of clinical notes, which is often restricted due to privacy concerns. The NLP Sandbox is an approach for…

Despite the observable benefit of Natural Language Processing (NLP) in processing a large amount of textual medical data within a limited time for information retrieval, a handful of research efforts have been devoted to uncovering novel…

Computation and Language · Computer Science 2024-06-04 Md Taimur Ahad
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