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Radiotherapy treatment planning currently requires many trail-and-error iterations between the planner and treatment planning system, as well as between the planner and physician for discussion/consultation. The physician's preferences for…

Medical Physics · Physics 2019-08-01 Dan Nguyen , Azar Sadeghnejad Barkousaraie , Chenyang Shen , Xun Jia , Steve Jiang

Non-coplanar Intensity-Modulated Radiation Therapy (IMRT) goes a step further by orienting the gantry carrying the radiation beam and the patient couch in a non-coplanar manner to accurately target the cancer region and better avoid…

Medical Physics · Physics 2023-05-16 Fang Guo , Franklin Okoli , Ulrike Schick , Dimitris Visvikis , Antoine Valeri , Julien Bert

Modern external beam cancer radiotherapy applies prescribed radiation doses to tumor targets while minimally affecting nearby vulnerable organs-at-risk (OARs). Creating a treatment plan is difficult and time-consuming with no guarantee of…

Medical Physics · Physics 2021-07-07 Lyndon Hibbard

Traditionally, optimization of radiation therapy (RT) treatment plans has been done before the initiation of RT course, using population-wide estimates for patients' response to therapy. However, recent technological advancements have…

Medical Physics · Physics 2021-02-15 Stefan C. M. ten Eikelder , Ali Ajdari , Thomas Bortfeld , Dick den Hertog

An Iterative Reanalysis Approximation (IRA) is integrated with the Moving Morphable Components (MMCs) based topology optimization (IRA-MMC) in this study. Compared with other classical topology optimization methods, the Finite Element (FE)…

Numerical Analysis · Computer Science 2018-10-17 Kangjia Mo , Hu Wang , Zhenxing Cheng , Yu Li

Machine learning (ML) is increasingly being used in image retrieval systems for medical decision making. One application of ML is to retrieve visually similar medical images from past patients (e.g. tissue from biopsies) to reference when…

This paper describes Motion Planning Networks (MPNet), a computationally efficient, learning-based neural planner for solving motion planning problems. MPNet uses neural networks to learn general near-optimal heuristics for path planning in…

Robotics · Computer Science 2020-06-30 Ahmed H. Qureshi , Yinglong Miao , Anthony Simeonov , Michael C. Yip

Optimization plays a central role in modern radiation therapy, where it is used to determine optimal treatment machine parameters in order to deliver precise doses adapted to each patient case. In general, solving the optimization problems…

Optimization and Control · Mathematics 2024-05-07 Felix Liu , Albin Fredriksson , Stefano Markidis

Clinical randomized controlled trials (RCTs) collect hundreds of measurements spanning various metric types (e.g., laboratory tests, cognitive/motor assessments, etc.) across 100s-1000s of subjects to evaluate the effect of a treatment, but…

Machine Learning · Computer Science 2024-06-25 Sayeri Lala , Niraj K. Jha

Solving different types of optimization models (including parameters fitting) for support vector machines on large-scale training data is often an expensive computational task. This paper proposes a multilevel algorithmic framework that…

Machine Learning · Statistics 2014-10-14 Talayeh Razzaghi , Ilya Safro

This study introduces a novel metric, Plan Aperture Modulation (PAM), developed to quantify the modulation of radiotherapy treatment plans. PAM aims to provide a clear geometric interpretation, addressing the limitations of previous…

Medical Physics · Physics 2025-11-25 Victor Hernandez , Iñigo Lara-Aristimuño , Ruben Abella , Jordi Saez

Fast and efficient motion planning algorithms are crucial for many state-of-the-art robotics applications such as self-driving cars. Existing motion planning methods become ineffective as their computational complexity increases…

Robotics · Computer Science 2019-02-26 Ahmed H. Qureshi , Anthony Simeonov , Mayur J. Bency , Michael C. Yip

Clinical machine learning faces a critical dilemma in high-stakes medical applications: algorithms achieving optimal diagnostic performance typically sacrifice the interpretability essential for physician decision-making, while…

Machine Learning · Computer Science 2025-09-23 Xiuqi Ge , Zhibo Yao , Yaosong Du

Multi-agent planning (MAP) approaches have been typically conceived for independent or loosely-coupled problems to enhance the benefits of distributed planning between autonomous agents as solving this type of problems require less…

Artificial Intelligence · Computer Science 2015-01-30 Alejandro Torreño , Eva Onaindia , Óscar Sapena

Global optimization of decision trees is a long-standing challenge in combinatorial optimization, yet such models play an important role in interpretable machine learning. Although the problem has been investigated for several decades, only…

Machine Learning · Computer Science 2026-02-03 Jiancheng Tu , Wenqi Fan , Zhibin Wu

We present a novel framework for addressing the challenges of multi-Agent planning and formation control within intricate and dynamic environments. This framework transforms the Multi-Agent Path Finding (MAPF) problem into a Multi-Agent…

Robotics · Computer Science 2024-05-14 Zong Chen , Songyuan Fa , Yiqun Li

Human Mesh Recovery (HMR) is the task of estimating a parameterized 3D human mesh from an image. There is a kind of methods first training a regression model for this problem, then further optimizing the pretrained regression model for any…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Yongwei Nie , Mingxian Fan , Chengjiang Long , Qing Zhang , Jian Zhu , Xuemiao Xu

This article introduces analytical techniques and a decision support tool to support capacity assessment and case mix planning (CMP) approaches previously created for hospitals. First, an optimization model is proposed to analyse the impact…

Artificial Intelligence · Computer Science 2025-01-06 Robert L Burdett , Paul corry , David Cook , Prasad Yarlagadda

An underlying structure in several sampling-based methods for continuous multi-robot motion planning (MRMP) is the tensor roadmap (TR), which emerges from combining multiple PRM graphs constructed for the individual robots via a tensor…

Robotics · Computer Science 2023-02-13 Dror Dayan , Kiril Solovey , Marco Pavone , Dan Halperin

Hyperparameter optimization (HPO) is a critical yet challenging aspect of machine learning model development, significantly impacting model performance and generalization. Traditional HPO methods often struggle with high dimensionality,…

Machine Learning · Computer Science 2025-05-29 Meher Bhaskar Madiraju , Meher Sai Preetam Madiraju
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