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A cardiac digital twin is a virtual replica of a patient-specific heart, mimicking its anatomy and physiology. A crucial step of building a cardiac digital twin is anatomical twinning, where the computational mesh of the digital twin is…

We present a Virtual Element Method (VEM) for a nonlocal reaction-diffusion system of the cardiac electric field. To this system, we analyze an $H^1(\Omega)$-conforming discretization by means of VEM which can make use of general polygonal…

Numerical Analysis · Mathematics 2018-04-04 Verónica Anaya , Mostafa Bendahmane , David Mora , Mauricio Sepúlveda

The human heart is a complex system exhibiting stochastic nature, as reflected in electrocardiogram (ECG) signals. ECG signal is a weak, non-stationary, and nonlinear signal, which indicates the health of a heart in terms of temporal…

Signal Processing · Electrical Eng. & Systems 2020-02-11 Chiranjit Maji , Pratyay Sengupta , Anandi Batabyal , Hirok Chaudhuri

Image-based computational models of the heart represent a powerful tool to shed new light on the mechanisms underlying physiological and pathological conditions in cardiac function and to improve diagnosis and therapy planning. However, in…

Tissues and Organs · Quantitative Biology 2021-01-15 Laura Marx , Justyna A. Niestrawska , Matthias A. F. Gsell , Federica Caforio , Gernot Plank , Christoph M. Augustin

Cardiac contraction is a rapid, coordinated process that unfolds across three-dimensional tissue on millisecond timescales. Traditional optical imaging is often inadequate for capturing dynamic cellular structure in the beating heart…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Yi Gong , Xinyuan Zhang , Jichen Chai , Yichen Ding , Yifei Lou

3D motion estimation from cine cardiac magnetic resonance (CMR) images is important for the assessment of cardiac function and the diagnosis of cardiovascular diseases. Current state-of-the art methods focus on estimating dense…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Qingjie Meng , Wenjia Bai , Declan P O'Regan , and Daniel Rueckert

An automatic classification method has been studied to effectively detect and recognize Electrocardiogram (ECG). Based on the synchronizing and orthogonal relationships of multiple leads, we propose a Multi-branch Convolution and Residual…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Bin Chen , Wei Guo , Bin Li , Rober K. F. Teng , Mingjun Dai , Jianping Luo , Hui Wang

The ability to map left ventricle (LV) myocardial motion using computed tomography angiography (CTA) is essential to diagnosing cardiovascular conditions and guiding interventional procedures. Due to their inherent locality, conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Shahar Zuler , Shai Tejman-Yarden , Dan Raviv

This work deals with the numerical solution of the monodomain and bidomain models of electrical activity of myocardial tissue. The bidomain model is a system consisting of a possibly degenerate parabolic PDE coupled with an elliptic PDE for…

Numerical Analysis · Mathematics 2008-07-03 Mostafa Bendahmane , Raimund Bürger , Ricardo Ruiz Baier

We present a new computational model for the numerical simulation of blood flow in the human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian Eulerian formulation to account for the endocardium motion…

Electrocardiography (ECG) is a non-invasive tool for predicting cardiovascular diseases (CVDs). Current ECG-based diagnosis systems show promising performance owing to the rapid development of deep learning techniques. However, the label…

Signal Processing · Electrical Eng. & Systems 2023-06-21 Rushuang Zhou , Lei Lu , Zijun Liu , Ting Xiang , Zhen Liang , David A. Clifton , Yining Dong , Yuan-Ting Zhang

Cardiac Magnetic Resonance (CMR) imaging serves as the gold-standard for evaluating cardiac morphology and function. Typically, a multi-view CMR stack, covering short-axis (SA) and 2/3/4-chamber long-axis (LA) views, is acquired for a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Yundi Zhang , Chen Chen , Suprosanna Shit , Sophie Starck , Daniel Rueckert , Jiazhen Pan

Electromyography (EMG)--based computational musculoskeletal modeling is a non-invasive method for studying musculotendon function, human movement, and neuromuscular control, providing estimates of internal variables like muscle forces and…

Machine Learning · Computer Science 2025-03-10 Rajnish Kumar , Tapas Tripura , Souvik Chakraborty , Sitikantha Roy

Accurate segmentation of cardiac structures can assist doctors to diagnose diseases, and to improve treatment planning, which is highly demanded in the clinical practice. However, the shortage of annotation and the variance of the data…

Image and Video Processing · Electrical Eng. & Systems 2022-08-05 Yao Zhang , Jiawei Yang , Feng Hou , Yang Liu , Yixin Wang , Jiang Tian , Cheng Zhong , Yang Zhang , Zhiqiang He

Electroanatomical mapping is a technique used in cardiology to create a detailed 3D map of the electrical activity in the heart. It is useful for diagnosis, treatment planning and real time guidance in cardiac ablation procedures to treat…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Sunil Mathew , Jasbir Sra , Daniel B. Rowe

Echocardiogram is the most commonly used imaging modality in cardiac assessment duo to its non-invasive nature, real-time capability, and cost-effectiveness. Despite its advantages, most clinical echocardiograms provide only two-dimensional…

Image and Video Processing · Electrical Eng. & Systems 2025-05-12 Xilin Gong , Yongkai Chen , Shushan Wu , Fang Wang , Ping Ma , Wenxuan Zhong

In the process of patient diagnosis, non-invasive measurements are widely used due to their low risks and quick results. Electrocardiogram (ECG), as a non-invasive method to collect heart activities, is used to diagnose cardiac conditions.…

Machine Learning · Computer Science 2025-12-11 Yuhao Xu , Jiaying Lu , Sirui Ding , Defu Cao , Xiao Hu , Carl Yang

Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world. Automated diagnosis studies have been constrained by underpowered single-center…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Akis Linardos , Kaisar Kushibar , Sean Walsh , Polyxeni Gkontra , Karim Lekadir

The electrocardiogram (ECG) is a vital tool for diagnosing heart diseases. However, many disease patterns are derived from outdated datasets and traditional stepwise algorithms with limited accuracy. This study presents a method for direct…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Oğuzhan Büyüksolak , İlkay Öksüz

Advancing human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) technology will lead to significant progress ranging from disease modeling, to drug discovery, to regenerative tissue engineering. Yet, alongside these potential…

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