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Cardiac Magnetic Resonance Imaging (CMR) is the gold standard for diagnosing cardiovascular diseases. Clinical diagnoses predominantly rely on magnitude-only Digital Imaging and Communications in Medicine (DICOM) images, omitting crucial…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Ruochen Li , Jiazhen Pan , Youxiang Zhu , Juncheng Ni , Daniel Rueckert

This paper proposes a method for simultaneous segmentation of multi-source images, using the multivariate mixture model (MvMM) and maximum of log-likelihood (LL) framework. The segmentation is a procedure of texture classification, and the…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Xiahai Zhuang

Extracellular matrix (ECM) remodeling is central to a wide variety of healthy and diseased tissue processes. Unfortunately, predicting ECM remodeling under various chemical and mechanical conditions has proven to be excessively challenging,…

Molecular Networks · Quantitative Biology 2026-05-26 Hasi Hays , William J. Richardson

Deep fully convolutional neural network (FCN) based architectures have shown great potential in medical image segmentation. However, such architectures usually have millions of parameters and inadequate number of training samples leading to…

Computer Vision and Pattern Recognition · Computer Science 2018-01-17 Mahendra Khened , Varghese Alex Kollerathu , Ganapathy Krishnamurthi

We provide a rather simple proof of a homogenization result for the bidomain model of cardiac electrophysiology. Departing from a microscopic cellular model, we apply the theory of two-scale convergence to derive the bidomain model. To…

Analysis of PDEs · Mathematics 2018-11-20 Erik Grandelius , Kenneth H. Karlsen

We present a novel microscopic tridomain model describing the electrical activity in cardiac tissue with dynamical gap junctions. The microscopic tridomain system consists of three PDEs modeling the tissue electrical conduction in the…

Analysis of PDEs · Mathematics 2022-06-01 Fakhrielddine Bader , Mostafa Bendahmane , Mazen Saad , Raafat Talhouk

Two crucial factors for accurate numerical simulations of cardiac electromechanics, which are also essential to reproduce the synchronous activity of the heart, are: i) accounting for the interaction between the heart and the circulatory…

We propose four novel mathematical models, describing the microscopic mechanisms of force generation in the cardiac muscle tissue, which are suitable for multiscale numerical simulations of cardiac electromechanics. Such models are based on…

Subcellular Processes · Quantitative Biology 2021-01-27 Francesco Regazzoni , Luca Dedè , Alfio Quarteroni

High failure rates in cardiac drug development necessitate virtual clinical trials via electrocardiogram (ECG) generation to reduce risks and costs. However, existing ECG generation models struggle to balance morphological realism with…

Machine Learning · Computer Science 2026-03-31 Qian Shao , Bang Du , Zepeng Li , Qiyuan Chen , Jiahe Chen , Hongxia Xu , Jimeng Sun , Jian Wu , Jintai Chen

Accurate 3D cardiac reconstruction from cine magnetic resonance imaging (cMRI) is crucial for improved cardiovascular disease diagnosis and understanding of the heart's motion. However, current cardiac MRI-based reconstruction technology…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Xiaoxiao He , Chaowei Tan , Ligong Han , Bo Liu , Leon Axel , Kang Li , Dimitris N. Metaxas

The inverse mechano-electrical problem in cardiac electrophysiology is the attempt to reconstruct electrical excitation or action potential wave patterns from the heart's mechanical deformation that occurs in response to electrical…

Image and Video Processing · Electrical Eng. & Systems 2021-11-10 Jan Christoph , Jan Lebert

The Electrocardiograph signal represents the heart's electrical activity while blood pressure results from the heart's mechanical activity. Previous studies have investigated how the heart's electrical and mechanical activities are related…

Signal Processing · Electrical Eng. & Systems 2020-08-25 Seyedeh Somayyeh Mousavi , Mostafa Charmi , Mohammad Firouzmand , Mohammad Hemmati , Maryam Moghadam , Yadollah Ghorbani

Cardiac image segmentation is essential for automated cardiac function assessment and monitoring of changes in cardiac structures over time. Inspired by coarse-to-fine approaches in image analysis, we propose a novel multitask compositional…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Abbas Khan , Muhammad Asad , Martin Benning , Caroline Roney , Gregory Slabaugh

Coronary arteries and their branches supply blood to myocardium. The obstruction of coronary arteries results in significant loss of myocardium, called acute myocardial infarction, and the number one cause of death globally. Hence,…

Computational Geometry · Computer Science 2017-08-31 Jehyun Chaa , Joonghyun Ryub , Jin-Ho Choi , Deok-Soo Kim

Surface electromyography (sEMG) recordings can be contaminated by electrocardiogram (ECG) signals when the monitored muscle is closed to the heart. Traditional signal processing-based approaches, such as high-pass filtering and template…

Signal Processing · Electrical Eng. & Systems 2025-02-20 Yu-Tung Liu , Kuan-Chen Wang , Rong Chao , Sabato Marco Siniscalchi , Ping-Cheng Yeh , Yu Tsao

LGE CMR is an efficient technology for detecting infarcted myocardium. An efficient and objective ventricle segmentation method in LGE can benefit the location of the infarcted myocardium. In this paper, we proposed an automatic framework…

Image and Video Processing · Electrical Eng. & Systems 2019-09-19 Yashu Liu , Wei Wang , Kuanquan Wang , Chengqin Ye , Gongning Luo

Automated segmentation of Cardiac Magnetic Resonance (CMR) plays a pivotal role in efficiently assessing cardiac function, offering rapid clinical evaluations that benefit both healthcare practitioners and patients. While recent research…

Image and Video Processing · Electrical Eng. & Systems 2024-06-14 Abdul Qayyum , Hao Xu , Brian P. Halliday , Cristobal Rodero , Christopher W. Lanyon , Richard D. Wilkinson , Steven Alexander Niederer

Cardiovascular Diseases (CVD) and strokes produce immense health and economic burdens globally. Coronary Artery Disease (CAD) is the most common type of cardiovascular disease. Coronary Angiography, which is an invasive treatment, is also…

Artificial Intelligence · Computer Science 2020-05-22 Ioannis Apostolopoulos , Peter Groumpos

Labelling data is expensive and time consuming especially for domains such as medical imaging that contain volumetric imaging data and require expert knowledge. Exploiting a larger pool of labeled data available across multiple centers,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-03 Daiqing Li , Amlan Kar , Nishant Ravikumar , Alejandro F Frangi , Sanja Fidler

Atlas-based approaches allow high-quality, patient-specific shape reconstructions of cardiac anatomy from sparse and/or noisy data such as point clouds. However, these methods are mainly prior-driven, so the impact of uncertainty can be…

Image and Video Processing · Electrical Eng. & Systems 2026-05-11 Jan Verhülsdonk , Thomas Grandits , Francisco Sahli Costabal , Thomas Beiert , Simone Pezzuto , Alexander Effland
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