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We propose a novel partitioned scheme based on Eikonal equations to model the coupled propagation of the electrical signal in the His-Purkinje system and in the myocardium for cardiac electrophysiology. This scheme allows, for the first…

Numerical Analysis · Mathematics 2024-12-19 Samuele Brunati , Michele Bucelli , Roberto Piersanti , Luca Dede' , Christian Vergara

Myocardial infarction (MI) is one of the most prevalent cardiovascular diseases with associated clinical decision-making typically based on single-valued imaging biomarkers. However, such metrics only approximate the complex 3D structure…

Computer Vision and Pattern Recognition · Computer Science 2023-07-17 Marcel Beetz , Yilong Yang , Abhirup Banerjee , Lei Li , Vicente Grau

Developing efficient path integral (PI) methods for atomistic simulations of vibrational spectra in heterogeneous condensed phases and interfaces has long been a challenging task. Here, we present the h-CMD method, short for hybrid centroid…

Chemical Physics · Physics 2025-05-08 Dil K. Limbu , Nathan London , Md Omar Faruque , Mohammad R. Momeni

Cardiovascular disease (CVD) is a leading cause of mortality worldwide. Electrocardiograms (ECGs) are the most widely used non-invasive tool for cardiac assessment, yet large, well-annotated ECG corpora are scarce due to cost, privacy, and…

Machine Learning · Computer Science 2025-11-14 Xiaoda Wang , Kaiqiao Han , Yuhao Xu , Xiao Luo , Yizhou Sun , Wei Wang , Carl Yang

Background: Extensive clinical evidence suggests that a preventive screening of coronary heart disease (CHD) at an earlier stage can greatly reduce the mortality rate. We use 64 two-dimensional speckle tracking echocardiography (2D-STE)…

Machine Learning · Statistics 2021-05-21 Jingyi Zhang , Huolan Zhu , Yongkai Chen , Chenguang Yang , Huimin Cheng , Yi Li , Wenxuan Zhong , Fang Wang

We develop a new meshfree geometric multilevel (MGM) method for solving linear systems that arise from discretizing elliptic PDEs on surfaces represented by point clouds. The method uses a Poisson disk sampling-type technique for coarsening…

Numerical Analysis · Mathematics 2022-04-14 Grady B. Wright , Andrew M. Jones , Varun Shankar

The realisation of precision cardiology requires novel techniques for the non-invasive characterisation of individual patients' cardiac function to inform therapeutic and diagnostic decision-making. The electrocardiogram (ECG) is the most…

Tissues and Organs · Quantitative Biology 2021-12-09 Julia Camps , Brodie Lawson , Christopher Drovandi , Ana Minchole , Zhinuo Jenny Wang , Vicente Grau , Kevin Burrage , Blanca Rodriguez

Time-evolving magnetohydrodynamic (MHD) coronal modeling, driven by a series of time-dependent photospheric magnetograms, represents a new generation of coronal simulations. This approach offers greater realism compared to traditional…

Deformation modeling of cardiac muscle is an important issue in the field of cardiac analysis. Many approaches have been developed to better estimate the cardiac muscle deformation, and to obtain a practical model to be used in diagnostic…

Computational Engineering, Finance, and Science · Computer Science 2015-12-01 Ahmadreza Baghaie , Hamid Abrishami Moghaddam

Wearable sensing devices, such as Electrocardiogram (ECG) heart-rate monitors, will play a crucial role in the future of digital health. This continuous monitoring leads to massive unlabeled data, incentivizing the development of…

Machine Learning · Computer Science 2025-03-03 Adtian Atienza , Gouthamaan Manimaran , Jakob E. Bardram , Sadasivan Puthusserypady

Electrocardiogram (ECG) is a widely used non-invasive diagnostic tool for heart diseases. Many studies have devised ECG analysis models (e.g., classifiers) to assist diagnosis. As an upstream task, researches have built generative models to…

Machine Learning · Computer Science 2023-05-30 Jintai Chen , Kuanlun Liao , Kun Wei , Haochao Ying , Danny Z. Chen , Jian Wu

Four-dimensional (4D) left ventricular myocardial velocity mapping (MVM) is a cardiac magnetic resonance (CMR) technique that allows assessment of cardiac motion in three orthogonal directions. Accurate and reproducible delineation of the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Yinzhe Wu , Suzan Hatipoglu , Diego Alonso-Álvarez , Peter Gatehouse , David Firmin , Jennifer Keegan , Guang Yang

This study introduces an improved VMD based signal decomposition methodology for non-contact heartbeat estimation using millimeterwave (mmWave) radar. Specifically, we first analyze the signal model of the mmWave radar system. The…

Signal Processing · Electrical Eng. & Systems 2025-02-18 Boyuan Gu , Yanhui Yang , Siyu You , Haiyang Sun , Jiahui Sun , Shisheng Guo

When modelling tissue-level cardiac electrophysiology, continuum approximations to the discrete cell-level equations are used to maintain computational tractability. One of the most commonly used models is represented by the bidomain…

Computational Engineering, Finance, and Science · Computer Science 2012-08-22 Doug Bruce , Pras Pathmanathan , Jonathan P. Whiteley

We present a mean-field approach to simulating merging processes of two spherical collisionless stellar systems. This approach is realized with a self-consistent field (SCF) method in which the full spatial dependence of the density and…

Instrumentation and Methods for Astrophysics · Physics 2019-04-17 Shunsuke Hozumi , Masaki Iwasawa , Keigo Nitadori

Computer modeling of multicellular systems has been a valuable tool for interpreting and guiding in vitro experiments relevant to embryonic morphogenesis, tumor growth, angiogenesis and, lately, structure formation following the printing of…

Biological Physics · Physics 2015-05-28 Elijah Flenner , Lorant Janosi , Bogdan Barz , Adrian Neagu , Gabor Forgacs , Ioan Kosztin

Accurate diagnosis is required before performing proper treatments for coronary heart disease. Machine learning based approaches have been proposed by many researchers to improve the accuracy of coronary heart disease diagnosis. Ensemble…

Machine Learning · Computer Science 2020-07-07 Kuntoro Adi Nugroho , Noor Akhmad Setiawan , Teguh Bharata Adji

Feature tracking Cardiac Magnetic Resonance (CMR) has recently emerged as an area of interest for quantification of regional cardiac function from balanced, steady state free precession (SSFP) cine sequences. However, currently available…

Computer Vision and Pattern Recognition · Computer Science 2017-04-13 Davis M. Vigneault , Weidi Xie , David A. Bluemke , J. Alison Noble

Computational fluid dynamics (CFD) simulation provides valuable information on blood flow from the vascular geometry. However, it requires extracting precise models of arteries from low-resolution medical images, which remains challenging.…

Computational Geometry · Computer Science 2023-06-14 Méghane Decroocq , Carole Frindel , Pierre Rougé , Makoto Ohta , Guillaume Lavoué

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) are a promising therapy for regenerating myocardium after infarction, but their use is limited by graft-related arrhythmias that frequently occur shortly after transplantation.…

Tissues and Organs · Quantitative Biology 2026-05-05 Suran Galappaththige , Vadim N Biktashev , Faisal J Alibhai , Michael Laflamme