Related papers: Existence results for a morphoelastic model
We propose a mathematical model that combines elastic, viscous and porous effects with growth or shrinkage due to microstructural changes. This phenomenon is important in tissue or tumor growth, as well as in dermal contraction. Although…
Using formal asymptotic methods we derive a free boundary problem representing one of the simplest mathematical descriptions of the growth and death of a tumour or other biological tissue. The mathematical model takes the form of a closed…
The mechanical behaviour of solid biological tissues has long been described using models based on classical continuum mechanics. However, the classical continuum theories of elasticity and viscoelasticity cannot easily capture the…
We investigate the evolution of tumor growth relying on a nonlinear model of partial differential equations which incorporates mechanical laws for tissue compression combined with rules for nutrients availability and drug application.…
We present a general approach to prove existence of solutions for optimal control problems not based on typical convexity conditions which quite often are very hard, if not impossible, to check. By taking advantage of several relaxations of…
In this paper we address some modelling issues related to biological growth. Our treatment is based on a recently-proposed, general formulation for growth within the context of Mixture Theory (Journal of the Mechanics and Physics of Solids,…
We focus on optimal control problems governed by elliptic, quasilinear PDEs. Though there are various examples of such problems in the literature, we make an attempt at describing some general principles by dealing with three basic…
This paper studies a discrete-time version of the Lucas-Uzawa endogenous growth model with physical and human capital in the presence of externalities. Existence of an optimal equilibrium is proved using tools from dynamic programming with…
We introduce modes of instantaneous optimal growth of free energy for the fully electromagnetic gyrokinetic equations. We demonstrate how these "optimal modes" arise naturally from the free energy balance equation, allowing its convenient…
This paper is concerned with the existence of optimal controls for backward stochastic partial differential equations with random coefficients, in which the control systems are represented in an abstract evolution form, i.e. backward…
We study a stochastic phase-field model for tumor growth dynamics coupling a stochastic Cahn-Hilliard equation for the tumor phase parameter with a stochastic reaction-diffusion equation governing the nutrient proportion. We prove strong…
Natural slender structures, such as plant leaves, petals, and tendrils, often exhibit complex three-dimensional (3D) morphologies-including twisting, helical coiling, and saddle-bending-driven by differential growth. The resulting internal…
We investigate the long-time dynamics and optimal control problem of a diffuse interface model that describes the growth of a tumor in presence of a nutrient and surrounded by host tissues. The state system consists of a Cahn-Hilliard type…
Recently, much attention has been given to a noteworthy property of some soft tissues: their ability to grow. Many attempts have been made to model this behaviour in biology, chemistry and physics. Using the theory of finite elasticity,…
We consider a free boundary problem for a system of PDEs, modeling the growth of a biological tissue. A morphogen, controlling volume growth, is produced by specific cells and then diffused and absorbed throughout the domain. The geometric…
We show that the system of equations describing a magnetoviscoelastic fluid in three dimensions can be cast as a quasilinear parabolic system. Using the theory of maximal $L_p$-regularity, we establish existence and uniqueness of local…
We study a relaxed formulation of the quasistatic evolution problem in the context of small strain associative elastoplasticity with softening. The relaxation takes place in spaces of generalized Young measures. The notion of solution is…
We consider a non-local tumour growth model of phase-field type, describing the evolution of tumour cells through proliferation in presence of a nutrient. The model consists of a coupled system, incorporating a non-local Cahn-Hilliard…
Various models of tumor growth are available in the litterature. A first class describes the evolution of the cell number density when considered as a continuous visco-elastic material with growth. A second class, describes the tumor as a…
The system is described by three mass-shell constraints. After a nonlinear transformation of the momenta, the analytic form taken by admissible interactions (allowing compatibility) is characterized in terms of the new variables. These…