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The challenges presented by the COVID-19 epidemic have created a renewed interest in the development of new methods to combat infectious diseases. A prominent property of the SARS-CoV-2 transmission is the significant fraction of…
In late 2019, a novel coronavirus, the SARS-CoV-2 outbreak was identified in Wuhan, China and later spread to every corner of the globe. Whilst the number of infection-induced deaths in Ghana, West Africa are minimal when compared with the…
Interactions between SARS-CoV-2 and human proteins (SARS-CoV-2 PPIs) cause information transfer through biochemical pathways that contribute to the immunopathology of COVID-19. Here, we present a communication network model of the immune…
In December 2019, a novel coronavirus (SARS-CoV-2) has been identified to cause acute respiratory disease in humans. An outbreak of this disease has been reported in mainland China with the city of Wuhan as the recognized epicenter. The…
Since the first case of COVID-19 disease in Wuhan in December 2019, there is a worldwide struggle to reduce the transmission of acute respiratory syndrome coronavirus SARS-CoV-2. Many countries worldwide decided to impose local lockdowns in…
Infectious diseases spread via pathogens such as viruses and bacteria. Airborne pathogen transmission via droplets is an important mode for infectious diseases. In this paper, the spreading mechanism of infectious diseases by airborne…
In times of outbreaks, an essential requirement for better monitoring is the evaluation of the number of undiagnosed infected individuals. An accurate estimate of this fraction is crucial for the assessment of the situation and the…
While facial coverings over the nose and mouth reduce the spread of the virus SARS-CoV-2 by filtration, masks capable of viral inactivation by heating could provide a complementary method to limit viral transmission. In this work, we…
In this paper, we estimate the seroprevalence against COVID-19 by country and derive the seroprevalence over the world. To estimate seroprevalence, we use serological surveys (also called the serosurveys) conducted within each country. When…
Globally the SARS-CoV-2 coronavirus has infected more than 59 million people and killed more than 1.39 million. Designing and monitoring interventions to slow and stop the spread of the virus require knowledge of how many people have been…
Summary: Polymerase chain reaction-based assays are the current gold standard for detecting and diagnosing SARS-CoV-2. However, as SARS-CoV-2 mutates, we need to constantly assess whether existing PCR-based assays will continue to detect…
The widely used gene quantisation technique, Lateral Flow Device (LFD), is now commonly used to detect the presence of SARS-CoV-2. It is enabling the control and prevention of the spread of the virus. Depending on the viral load, LFD have…
We investigate transmission dynamics for SARS-CoV-2 on a real network of classes at Simon Fraser University, a medium-sized school in Western Canada. Outbreaks are simulated over the course of one semester across numerous parameter settings…
The spreading of the virus-containing droplets exhaled during respiratory events, e.g., cough, is an issue of paramount importance for the prevention of many infections such as COVID-19. According to the scientific literature, remarkable…
The genomic ssRNA of coronaviruses is packaged within a helical nucleocapsid. Due to transitional symmetry of a helix, weakly specific cooperative interaction between ssRNA and nucleocapsid proteins leads to the natural selection of…
A comprehensive retrospective analysis of public health interventions, such as large scale testing, quarantining, and contact tracing, can help identify mechanisms most effective in mitigating COVID-19. We investigate China based SARS-CoV-2…
SARS-CoV-2 has disrupted the life of billions of people around the world since the first outbreak was officially declared in China at the beginning of 2020. Yet, important questions such as how deadly it is or its degree of spread within…
The clinical spectrum of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the strain of coronavirus that caused the COVID-19 pandemic, is broad, extending from asymptomatic infection to severe immunopulmonary reactions that, if…
In this worldwide spread of SARS-CoV-2 (COVID-19) infection, it is of utmost importance to detect the disease at an early stage especially in the hot spots of this epidemic. There are more than 110 Million infected cases on the globe,…
SARS-CoV-2 is colloquially known as COVID-19 that had an initial outbreak in December 2019. The deadly virus has spread across the world, taking part in the global pandemic disease since March 2020. In addition, a recent variant of…