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Quantitative assessment of cardiac left ventricle (LV) morphology is essential to assess cardiac function and improve the diagnosis of different cardiovascular diseases. In current clinical practice, LV quantification depends on the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-25 Sulaiman Vesal , Mingxuan Gu , Andreas Maier , Nishant Ravikumar

Purpose: Magnetization transfer (MT) and inhomogeneous MT (ihMT) contrasts are used in MRI to provide information about macromolecular tissue content. In particular, MT is sensitive to macromolecules and ihMT appears to be specific to…

Electroanatomical mapping is a technique used in cardiology to create a detailed 3D map of the electrical activity in the heart. It is useful for diagnosis, treatment planning and real time guidance in cardiac ablation procedures to treat…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Sunil Mathew , Jasbir Sra , Daniel B. Rowe

Cardiac MRI is limited by long acquisition times, which can lead to patient discomfort and motion artifacts. We aim to accelerate Cartesian dynamic cardiac MRI by learning efficient, scan-adaptive undersampling patterns that preserve…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Siddhant Gautam , Angqi Li , Prachi P. Agarwal , Anil K. Attili , Jeffrey A. Fessler , Nicole Seiberlich , Saiprasad Ravishankar

Cardiovascular magnetic resonance imaging is a powerful diagnostic tool for assessing cardiac structure and function. However, traditional breath-held imaging protocols pose challenges for patients with arrhythmias or limited breath-holding…

Purpose: To develop a model-based nonlinear reconstruction for simultaneous water-specific $T_{1}$, $R_{2}^{*}$, $B_{0}$ field and/or fat fraction (FF) mapping using single-shot inversion-recovery (IR) multi-echo radial FLASH. Methods: The…

Magnetic resonance fingerprinting (MRF) provides a unique concept for simultaneous and fast acquisition of multiple quantitative MR parameters. Despite acquisition efficiency, adoption of MRF into the clinics is hindered by its dictionary…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Fabian Balsiger , Alain Jungo , Olivier Scheidegger , Pierre G. Carlier , Mauricio Reyes , Benjamin Marty

This work addresses the problem of estimating proton density and T1 maps from two partially sampled K-space scans such that the total acquisition time remains approximately the same as a single scan. Existing multi parametric non linear…

Computer Vision and Pattern Recognition · Computer Science 2015-12-25 Anupriya Gogna , Angshul Majumdar

Purpose: Magnetization transfer (MT) has been identified as the principal source of $T_1$ variability in the MRI literature. This study assesses the sensitivity of established $T_1$ mapping techniques to variations in the underlying MT…

Medical Physics · Physics 2025-12-15 Jakob Assländer

Purpose: To develop and evaluate a free-breathing respiratory motion compensated 4D (3D+respiration) $T_2$-weighted turbo spin echo sequence with application to radiology and MR-guided radiotherapy. Methods: k-space data are continuously…

Arrhythmias are potentially fatal disruptions to the normal heart rhythm, but their underlying dynamics is still poorly understood. Theoretical modeling is an important tool to fill this gap. Typical studies often employ detailed…

Tissues and Organs · Quantitative Biology 2022-03-08 R. V. Stenzinger , M. H. R. Tragtenberg

Purpose: To identify the predominant source of the $T_1$ variability described in the literature, which ranges from 0.6-1.1 s for brain white matter at 3 T. Methods: 25 $T_1$-mapping methods from the literature were simulated with a…

Medical Physics · Physics 2025-01-07 Jakob Assländer

Superparamagnetic iron oxide nanoparticles (SPIONs) such as ferumoxytol are promising theranostic agents detectable with MRI. Relaxation time mapping offers reproducible, quantitative biomarkers of SPION distribution, but conventional…

Background: Several studies have shown that both respiratory and cardiac motion can be extracted from the Pilot Tone (PT) signal successfully. However, most of these studies were performed in healthy volunteers. In addition, validating PT…

Signal Processing · Electrical Eng. & Systems 2024-02-29 Chong Chen , Yingmin Liu , Orlando P. Simonetti , Matthew Tong , Ning Jin , Mario Bacher , Peter Speier , Rizwan Ahmad

Recovering the T2 distribution from multi-echo T2 magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this…

Contemporary cardiovascular management involves complex consideration and integration of multimodal cardiac datasets, where each modality provides distinct but complementary physiological characteristics. While the effective integration of…

Magnetic resonance (MR)-$T_2^*$ mapping is widely used to study hemorrhage, calcification and iron deposition in various clinical applications, it provides a direct and precise mapping of desired contrast in the tissue. However, the long…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Shuai Huang , James J. Lah , Jason W. Allen , Deqiang Qiu

Stroke is a leading cause of disability and death. Effective treatment decisions require early and informative vascular imaging. 4D perfusion imaging is ideal but rarely available within the first hour after stroke, whereas plain CT and CTA…

Computer Vision and Pattern Recognition · Computer Science 2024-04-08 Chayanin Tangwiriyasakul , Pedro Borges , Stefano Moriconi , Paul Wright , Yee-Haur Mah , James Teo , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

A central goal of modern magnetic resonance imaging (MRI) is to reduce the time required to produce high-quality images. Efforts have included hardware and software innovations such as parallel imaging, compressed sensing, and deep…

Medical Physics · Physics 2023-03-27 Yihong Xu , Chad W. Farris , Stephan W. Anderson , Xin Zhang , Keith A. Brown

Recovering the 3D motion of the heart from cine cardiac magnetic resonance (CMR) imaging enables the assessment of regional myocardial function and is important for understanding and analyzing cardiovascular disease. However, 3D cardiac…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Qingjie Meng , Chen Qin , Wenjia Bai , Tianrui Liu , Antonio de Marvao , Declan P O'Regan , Daniel Rueckert