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Short-range repulsion governs the dynamics of matter from atoms to animals. Using theory, simulations, and experiments, we find that an ensemble of repulsive particles spreads compactly with a sharp boundary, in contrast to the diffusive…

Soft Condensed Matter · Physics 2024-06-17 Matan Yah Ben Zion , Naomi Oppenheimer

A wide spectrum of Peritrichous bacteria undergo considerable physiological changes when they are inoculated onto nutrition-rich surfaces and exhibit a rapid and collective migration denoted as swarming. Thereby, the length of such swarmer…

Biological Physics · Physics 2016-10-25 Thomas Eisenstecken , Jinglei Hu , Roland G. Winkler

Cell motility in higher organisms (eukaryotes) is crucial to biological functions ranging from wound healing to immune response, and also implicated in diseases such as cancer. For cells crawling on hard surfaces, significant insights into…

Soft Condensed Matter · Physics 2015-06-24 E. Tjhung , A. Tiribocchi , D. Marenduzzo , M. E. Cates

We numerically investigate the mean exit time of an inertial active Brownian particle from a circular cavity with single or multiple exit windows. Our simulation results witness distinct escape mechanisms depending upon the relative…

Statistical Mechanics · Physics 2025-08-18 Tanwi Debnath , Pinaki Chaudhury , Taritra Mukherjee , Debasish Mondal , Pulak K. Ghosh

Sticky Brownian motion is the simplest example of a diffusion process that can spend finite time both in the interior of a domain and on its boundary. It arises in various applications such as in biology, materials science, and finance.…

Numerical Analysis · Mathematics 2020-07-21 Nawaf Bou-Rabee , Miranda Holmes-Cerfon

The interaction between nano- or micro-sized particles and cell membranes is of crucial importance in many biological and biomedical applications such as drug and gene delivery to cells and tissues. During their cellular uptake, the…

The escape rate of a Brownian particle over a potential barrier is accurately described by the Kramers theory. A quantitative theory explicitly taking the activity of Brownian particles into account has been lacking due to the inherently…

Soft Condensed Matter · Physics 2017-02-01 A. Sharma , R. Wittmann , J. M. Brader

We propose a minimal model, based on active Brownian particles, for the dynamics of cells confined in a two-state micropattern, composed of two rectangular boxes connected by a bridge, and investigate the transition statistics. A transition…

Soft Condensed Matter · Physics 2022-05-13 F. M. R. Safara , H. P. Melo , M. M. Telo da Gama , N. A. M. Araújo

Minimal models of active Brownian colloids consisting of self-propelled spherical particles with purely repulsive interactions have recently been identified as excellent quantitative testing grounds for theories of active matter and have…

Soft Condensed Matter · Physics 2016-04-12 M. Cristina Marchetti , Yaouen Fily , Silke Henkes , Adam Patch , David Yllanes

We propose a model for the structure formation of jellyfish swimming based on active Brownian particles. We address the phenomena of counter-current swimming, avoidance of turbulent flow regions and foraging. We motivate corresponding…

Adaptation and Self-Organizing Systems · Physics 2023-04-21 Erik Gengel , Zafrir Kuplik , Dror Angel , Eyal Heifetz

After summarizing basic features of self-organization such as entropy export, feedbacks and nonlinear dynamics, we discuss several examples in biology. The main part of the paper is devoted to a model of active Brownian motion that allows a…

Statistical Mechanics · Physics 2007-05-23 Werner Ebeling , Frank Schweitzer

Motile cells often explore natural environments characterized by a high degree of structural complexity. Moreover cell motility is also intrinsically noisy due to spontaneous random reorientation and speed fluctuations. This interplay of…

Run-and-tumble is a basic model of persistent motion and a motility strategy widespread in micro-organisms and individual cells. In many natural settings, movement occurs in the presence of confinement. While accumulation at the surface has…

Soft Condensed Matter · Physics 2024-04-12 T. Pietrangeli , C. Ybert , C. Cottin-Bizonne , F. Detcheverry

Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…

Quantitative Methods · Quantitative Biology 2026-05-20 Antoine Diez , Jean Feydy

Thermally activated escape of a Brownian particle over a potential barrier is well understood within Kramers theory. When subjected to an external magnetic field, the Lorentz force slows down the escape dynamics via a rescaling of the…

Statistical Mechanics · Physics 2022-08-10 Iman Abdoli , Jens-Uwe Sommer , Hartmut Löwen , Abhinav Sharma

In nature, microorganisms must often cope with hostile environmental conditions. To do so they have developed sophisticated cooperative behavior and intricate communication capabilities, such as: direct cell-cell physical interactions via…

Condensed Matter · Physics 2007-05-23 Eshel Ben-Jacob , Inon Cohen , Ido Golding , Yonathan Kozlovsky

Nonergodicity observed in single-particle tracking experiments is usually modeled by transient trapping rather than spatial disorder. We introduce models of a particle diffusing in a medium consisting of regions with random sizes and random…

Soft Condensed Matter · Physics 2014-09-23 P. Massignan , C. Manzo , J. A. Torreno-Pina , M. F. García-Parajo , M. Lewenstein , G. J. Lapeyre

In this work we approach cell migration under a large-scale assumption, so that the system reduces to a particle in motion. Unlike classical particle models, the cell displacement results from its internal activity: the cell velocity is a…

Cell Behavior · Quantitative Biology 2018-08-02 Christèle Etchegaray , Nicolas Meunier

The transport of active particles may occur in complex environments, in which it emerges from the interplay between the mobility of the active components and the quenched disorder of the environment. Here we explore structural and dynamical…

Soft Condensed Matter · Physics 2023-03-31 Fergus J. Moore , John Russo Tanniemola B. Liverpool , C. Patrick Royall

The Brownian dynamics of a single microorganism coupled by chemotaxis to a diffusing concentration field which is secreted by the microorganism itself is studied by computer simulations in spatial dimensions $d=1,2,3$. Both cases of a…

Soft Condensed Matter · Physics 2015-05-13 Ankush Sengupta , Sven van Teeffelen , Hartmut Löwen
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