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We report a simulation study on the narrow escape kinetics of a Chiral Active Particle (CAP) confined to a circular domain with a narrow escape opening. The studys main objective is to optimize the CAPs escape changes as a function of the…

Soft Condensed Matter · Physics 2023-12-05 Alakesh Upadhyaya , Venkata Sathish Akella

A one-dimensional system of nonintersecting Brownian particles is constructed as the diffusion scaling limit of Fisher's vicious random walk model. $N$ Brownian particles start from the origin at time $t=0$ and undergo mutually avoiding…

Statistical Mechanics · Physics 2009-11-10 Taro Nagao

The motility of microorganisms is influenced greatly by their hydrodynamic interactions with the fluidic environment they inhabit. We show by direct experimental observation of the bi-flagellated alga Chlamydomonas reinhardtii that fluid…

Biological Physics · Physics 2015-11-03 Boyang Qin , Arvind Gopinath , Jing Yang , Jerry P Gollub , Paulo E Arratia

A Brownian particle with diffusion coefficient $D$ is confined to a bounded domain of volume $V$ in $\rR^3$ by a reflecting boundary, except for a small absorbing window. The mean time to absorption diverges as the window shrinks, thus…

Mathematical Physics · Physics 2007-05-23 A. Singer , Z. Schuss , D. Holcman , R. S. Eisenberg

Confined motions in complex environments are ubiquitous in microbiology. These situations invariably involve the intricate coupling between fluid flow, soft boundaries, surface forces and fluctuations. In the present study, such a coupling…

Soft Condensed Matter · Physics 2024-05-24 Nicolas Fares , Maxime Lavaud , Zaicheng Zhang , Aditya Jha , Yacine Amarouchene , Thomas Salez

In natural environments, solid surfaces present both opportunities and challenges for bacteria. On one hand, they serve as platforms for biofilm formation, crucial for bacterial colonization and resilience in harsh conditions. On the other…

Biological Physics · Physics 2025-07-01 Antai Tao , Guangzhe Liu , Rongjing Zhang , Junhua Yuan

The escape dynamics of sticky particles from textured surfaces is poorly understood despite importance to various scientific and technological domains. In this work, we address this challenge by investigating the escape time of adsorbates…

Statistical Mechanics · Physics 2025-07-15 Yuval Scher , Shlomi Reuveni , Denis S. Grebenkov

In a bilayered system of particles with wake-mediated interactions, the action-reaction symmetry for the effective forces between particles of different layers is broken. Under quite general conditions we show that, if the interaction…

Statistical Mechanics · Physics 2016-06-22 Jörg Bartnick , Andreas Kaiser , Hartmut Löwen , Alexei Ivlev

The escape of particles through a narrow absorbing gate in confined domains is a abundant phenomenon in various systems in physics, chemistry and molecular biophysics. We consider the narrow escape problem in a cellular flow when the two…

Statistical Mechanics · Physics 2018-12-04 Hui Wang , Jinqiao Duan , Xianguo Geng , Ying Chao

Diffusion through semipermeable structures arises in a wide range of processes in the physical and life sciences. Examples at the microscopic level range from artificial membranes for reverse osmosis to lipid bilayers regulating molecular…

Statistical Mechanics · Physics 2023-01-11 Paul C Bressloff

A certain class of viruses replicates inside a cell if they can enter the nucleus through one of many small target pores, before being permanently trapped or degraded. We adopt for viral motion a switching stochastic process model and we…

Subcellular Processes · Quantitative Biology 2016-07-20 Thibault Lagache , David Holcman

Cell migration often exhibits long-range temporal correlations and anomalous diffusion, even in the absence of external guidance cues such as chemical gradients or topographical constraints. These observations raise a fundamental question:…

Quantitative Methods · Quantitative Biology 2025-11-25 Gustavo Cornejo-Olea , Lucas Buvinic , Jerome Darbon , Radek Erban , Andrea Ravasio , Anastasios Matzavinos

The movement of organisms and cells can be governed by occasional long distance runs, according to an approximate L\'evy walk. For T cells migrating through chronically-infected brain tissue, runs are further interrupted by long pauses, and…

Biological Physics · Physics 2020-03-06 Gissell Estrada-Rodriguez , Heiko Gimperlein , Kevin J. Painter , Jakub Stocek

Single-file diffusion is a ubiquitous physical process exploited by living and synthetic systems to exchange molecules with their environment. It is paramount quantifying the escape time needed for single files of particles to exit from…

Soft Condensed Matter · Physics 2016-07-25 Emanuele Locatelli , Matteo Pierno , Fulvio Baldovin , Enzo Orlandini , Yizhou Tan , Stefano Pagliara

In colloidal systems, Brownian motion emerges from the massive separation of time and length scales associated to characteristic dynamics of the solute and solvent constituents. This separation of scales produces several temporal regimes in…

Many cell types display random motility on two-dimensional substrates, but crawl persistently in a single direction when confined in a microchannel or on an adhesive micropattern. Does this imply that the motility mechanism of confined…

Biological Physics · Physics 2014-06-13 Brian A. Camley , Wouter-Jan Rappel

We study the mean first exit time $T_{\ve}$ of a particle diffusing in a circular or a spherical micro-domain with an impenetrable confining boundary containing a small escape window (EW) of an angular size $\ve$. Focusing on the effects of…

Other Condensed Matter · Physics 2017-01-27 Denis S Grebenkov , Gleb Oshanin

Microorganisms swimming through viscous fluids imprint their propulsion mechanisms in the flow fields they generate. Extreme confinement of these swimmers between rigid boundaries often arises in natural and technological contexts, yet…

Soft Condensed Matter · Physics 2022-01-26 Debasmita Mondal , Ameya G. Prabhune , Sriram Ramaswamy , Prerna Sharma

Systems comprised of self-steering active Brownian particles are studied via simulations for a minimal cognitive flocking model. The dynamics of the active Brownian particles is extended by an orientational response with limited…

Soft Condensed Matter · Physics 2024-06-04 Rajendra Singh Negi , Roland G. Winkler , Gerhard Gompper

The motility of eukaryotic cells is strongly influenced by their environment, with confined cells often developing qualitatively different motility patterns from those migrating on simple two-dimensional substrates. Recent experiments,…

Cell Behavior · Quantitative Biology 2024-12-24 Pedrom Zadeh , Brian A. Camley