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In many adult tissues, stem cells and differentiated cells are not homogeneously distributed : stem cells are arranged in periodic "niches", and differentiated cells are constantly produced and migrate out of these niches. In this article,…

Biological Physics · Physics 2016-03-23 Edouard Hannezo , Alice Coucke , Jean-François Joanny

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

Viewed under a fluorescence microscope, the actomyosin cytoskeleton presents vivid streaks of lines together with persistent oscillatory waves. Using an active hydrodynamic approach, we show how a uniform distribution of single or mixture…

Soft Condensed Matter · Physics 2025-04-25 Ayan Roychowdhury , Saptarshi Dasgupta , Madan Rao

We study the collective dynamics of noise-driven excitable elements, so-called active rotators. Crucially here, the natural frequencies and the individual coupling strengths are drawn from some joint probability distribution. Combining a…

Disordered Systems and Neural Networks · Physics 2014-08-18 Bernard Sonnenschein , Thomas K. DM. Peron , Francisco A. Rodrigues , Jürgen Kurths , Lutz Schimansky-Geier

Multiple dissipative self-assembly protocols designed to create novel structures or to reduce kinetic traps have recently emerged. Specifically, temporal oscillations of particle interactions have been shown effective at both aims, but…

Soft Condensed Matter · Physics 2024-10-25 Jessica K. Niblo , Jacob R. Swartley , Zhongmin Zhang , Kateri H. DuBay

We aim to understand the formation of abnormal waves of activity from myocardial regions with diminished cell-to-cell coupling. In route to this goal, we studied the behavior of a heterogeneous myocyte network in which a sharp coupling…

Tissues and Organs · Quantitative Biology 2009-11-13 V. N. Biktashev , A. Arutunyan , N. A. Sarvazyan

Models of active nematics in biological systems normally require complexity arising from the hydrodynamics involved at the microscopic level as well as the viscoelastic nature of the system. Here we show that a minimal, space-independent,…

Soft Condensed Matter · Physics 2022-06-27 Emmanuel L. C. VI M. Plan , Huong Le Thi , Julia M. Yeomans , Amin Doostmohammadi

We continue the work of a series of previous studies of a mathematical model that describes the mean-field limit behavior of a homogeneous network of excitatory point spiking neurons. Contrary to other models, here noise is intrinsic to the…

Neurons and Cognition · Quantitative Biology 2017-07-20 Guillem Via

The well-defined but intricate course of time evolution exhibited by many naturally occurring phenomena suggests some source of dynamic order sustaining it. In spite of its obviousness as a problem, it has remained absent from the…

Adaptation and Self-Organizing Systems · Physics 2021-03-02 R. Herrero , J. Farjas , F. Pi , G. Orriols

We use numerical simulations to study the dynamics of dense assemblies of self-propelled particles in the limit of extremely large, but finite, persistence times. In this limit, the system evolves intermittently between mechanical…

Soft Condensed Matter · Physics 2023-06-09 Yann-Edwin Keta , Rituparno Mandal , Peter Sollich , Robert L. Jack , Ludovic Berthier

Many physical, chemical and biological processes rely on intrinsic oscillations to employ resonance responses to external stimuli of certain frequency. Such resonance phenomena in biological systems are typically explained by one of two…

Biological active matter is typically tightly coupled to chemical reaction networks affecting its assembly-disassembly dynamics and stress generation. We show that localized states can emerge spontaneously if assembly of active matter is…

Biological Physics · Physics 2023-12-15 Luca Barberi , Karsten Kruse

The interplay between activity and elasticity often found in active and living systems triggers a plethora of autonomous behaviors ranging from self-assembly and collective motion to actuation. Amongst these, spontaneous self-oscillations…

Soft Condensed Matter · Physics 2023-04-07 Ellen Zheng , Martin Brandenbourger , Louis Robinet , Peter Schall , Edan Lerner , Corentin Coulais

We discuss the dynamics of classical Dicke-type models, aiming to clarify the mechanisms by which coherent states could develop in potentially non-equilibrium systems such as semiconductor microcavities. We present simulations of an…

Strongly Correlated Electrons · Physics 2011-11-09 P. R. Eastham

Bacteria can form a great variety of spatially heterogeneous cell density patterns, ranging from simple concentric rings to dynamical spiral waves appearing in growing colonies. These pattern formation phenomena are important as they…

Populations and Evolution · Quantitative Biology 2025-01-17 John S. Chuang , Riccardo Rao , Stanislas Leibler

The mathematical theory of pattern formation in electrically coupled networks of excitable neurons forced by small noise is presented in this work. Using the Freidlin-Wentzell large deviation theory for randomly perturbed dynamical systems…

Pattern Formation and Solitons · Physics 2012-06-05 Georgi S. Medvedev , Svitlana Zhuravytska

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

Neurons and Cognition · Quantitative Biology 2018-06-20 Rodrigo F. O. Pena , Michael A. Zaks , Antonio C. Roque

We propose an alternative to the standard mechanisms for the formation of rogue waves in a non-conservative, nonlinear lattice dynamical system. We consider an ODE system that features regular periodic bursting arising from forced symmetry…

Pattern Formation and Solitons · Physics 2022-08-17 Priya Subramanian , Edgar Knobloch , P. G. Kevrekidis

A variety of physical, social and biological systems generate complex fluctuations with correlations across multiple time scales. In physiologic systems, these long-range correlations are altered with disease and aging. Such correlated…

Other Quantitative Biology · Quantitative Biology 2009-11-10 Luis A. N. Amaral , Albert Diaz-Guilera , Andre A. Moreira , Ary L. Goldberger , Lewis A. Lipsitz

A number of biological processes, such as embryo development, cancer metastasis or wound healing, rely on cells moving in concert. The mechanisms leading to the emergence of coordinated motion remain however largely unexplored. Although…

Cell Behavior · Quantitative Biology 2011-08-23 Alexandre J Kabla
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