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Epithelia form protective barriers in multicellular organisms. To maintain homeostasis, they must be able to regenerate and heal damaged areas. This occurs through collective cell migration, during which finger-like protrusions commonly…

When a dynamical system contains several different modes of oscillations it may behave in a variety of ways: If the modes oscillate at their own individual frequencies, it exhibits quasiperiodic behavior; when the modes lock to one another…

Chaotic Dynamics · Physics 2012-01-04 Mogens H. Jensen , Leo P. Kadanoff

Experiments show that the movement of eukaryotic cells is regulated by a process of phase separation of two competing enzymes on the cell membrane, that effectively amplifies shallow external gradients of chemical attractant. Notably, the…

Statistical Mechanics · Physics 2008-12-19 Teresa Ferraro , Antonio de Candia , Andrea Gamba , Antonio Coniglio

The nature of emergent collective behaviors of moving physical agents interacting with their neighborhood is a long-standing open issue in physical and biological systems alike. This calls for studies on the control of synchronization and…

Statistical Mechanics · Physics 2017-08-11 Tirthankar Banerjee , Abhik Basu

Oscillatory activities are widely observed in specific frequency bands of recorded field potentials in different brain regions, and play critical roles in processing neural information. Understanding the structure of these oscillatory…

Neurons and Cognition · Quantitative Biology 2015-07-23 Pengsheng Zheng

We study numerically the phases and dynamics of a dense collection of self-propelled particles with soft repulsive interactions in two dimensions. The model is motivated by recent in vitro experiments on confluent monolayers of migratory…

Soft Condensed Matter · Physics 2015-05-28 Silke Henkes , Yaouen Fily , M. Cristina Marchetti

Colloidal particles can self-assemble into various ordered structures in fluid flows that have potential applications in biomedicine, materials synthesis and encryption. These dynamic processes are also of fundamental interest for probing…

Soft Condensed Matter · Physics 2017-01-31 Yu Abe , Bo Zhang , Leonardo Gordillo , Alireza Mohammad Karim , Lorraine F. Francis , Xiang Cheng

We study the collective dynamics of self-propelled rods in an inhomogeneous motility field. At the interface between two regions of constant but different motility, a smectic rod layer is spontaneously created through aligning interactions…

Soft Condensed Matter · Physics 2018-02-14 Jens Grauer , Hartmut Löwen , Liesbeth M. C. Janssen

The cellular environment, characterized by its intricate composition and spatial organization, hosts a variety of organelles, ranging from membrane-bound ones to membraneless structures that are formed through liquid-liquid phase…

Soft Condensed Matter · Physics 2026-03-09 Gregor Häfner , Marcus Müller

We report on self-induced switchings between multiple distinct space--time patterns in the dynamics of a spatially extended excitable system. These switchings between low-amplitude oscillations, nonlinear waves, and extreme events strongly…

Chaotic Dynamics · Physics 2016-03-21 Gerrit Ansmann , Klaus Lehnertz , Ulrike Feudel

Cells in tissues can organize into a broad spectrum of structures according to their function. Drastic changes of organization, such as epithelial-mesenchymal transitions or the formation of spheroidal aggregates, are often associated…

Biological Physics · Physics 2016-12-22 Bart Smeets , Ricard Alert , Jiri Pesek , Ignacio Pagonabarraga , Herman Ramon , Romaric Vincent

We propose a model for the dynamics of a probe embedded in a living cell, where both thermal fluctuations and nonequilibrium activity coexist. The model is based on a confining harmonic potential describing the elastic cytoskeletal matrix,…

Biological Physics · Physics 2015-06-18 É. Fodor , M. Guo , N. S. Gov , P. Visco , D. A. Weitz , F. van Wijland

We present a generic mechanism by which reproducing microorganisms, with a diffusivity that depends on the local population density, can form stable patterns. It is known that a decrease of swimming speed with density can promote separation…

Populations and Evolution · Quantitative Biology 2010-07-13 M. E. Cates , D. Marenduzzo , I. Pagonabarraga , J. Tailleur

Thanks to a constant energy input, active matter can self-assemble into phases with complex architectures and functionalities such as living clusters that dynamically form, reshape and break-up, which are forbidden in equilibrium materials…

Soft Condensed Matter · Physics 2019-03-27 Falko Schmidt , Benno Liebchen , Hartmut Löwen , Giovanni Volpe

Individual cellular automata rules are attractive models for a range of biological and physical self-assembling systems. While coexpression and coevolution are common in such systems, ensembles of cellular automata rules remain poorly…

Cellular Automata and Lattice Gases · Physics 2007-07-26 Alexander D. Wissner-Gross

Collective improvisation in dance provides a rich natural laboratory for studying emergent coordination in coupled neuro-motor systems. Here, we investigate how training shapes spontaneous synchronization patterns in both movement and brain…

The study of deterministic chaos continues to be one of the important problems in the field of nonlinear dynamics. Interest in the study of chaos exists both in low-dimensional dynamical systems and in large ensembles of coupled…

Chaotic Dynamics · Physics 2021-06-30 V. O. Munyaev , D. S. Khorkin , M. I. Bolotov , L. A. Smirnov , G. V. Osipov

Complexity in the temporal organization of neural systems may be a reflection of the diversity of its neural constituents. These constituents, excitatory and inhibitory neurons, comprise an invariant ratio in vivo and form the substrate for…

Neurons and Cognition · Quantitative Biology 2015-05-18 Xin Chen , Rhonda Dzakpasu

In equilibrium, the physical properties of matter are set by the interactions between the constituents. In contrast, the energy input of the individual components controls the behavior of synthetic or living active matter. Great progress…

Soft Condensed Matter · Physics 2025-08-29 Q. Martinet , Y. Li , A. Aubret , E. Hannezo , J. Palacci

We extend a model for the morphology and dynamics of a crawling eukaryotic cell to describe cells on micropatterned substrates. This model couples cell morphology, adhesion, and cytoskeletal flow in response to active stresses induced by…

Cell Behavior · Quantitative Biology 2015-06-17 Brian A. Camley , Yanxiang Zhao , Bo Li , Herbert Levine , Wouter-Jan Rappel