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We study the Suscectible-Infected-Recovered-Susceptible (SIRS) epidemic model on deterministic networks. For connected but otherwise general interaction patterns and heterogeneous recovery and loss-of-immunity rates, we identify a…

Systems and Control · Electrical Eng. & Systems 2026-04-24 Giulia Gatti , Giacomo Como

In the face of an infectious disease, a key epidemiological measure is the basic reproduction number, which quantifies the average secondary infections caused by a single case in a susceptible population. In practice, the effective…

Physics and Society · Physics 2025-03-11 Xin-Jian Xu , Song-Jie He , Li-Jie Zhang

Motivated by the question of optimal vaccine allocation strategies in heterogeneous population for epidemic models, we study various properties of the \emph{effective reproduction number}. In the simplest case, given a fixed, non-negative…

Optimization and Control · Mathematics 2022-11-23 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

The reproductive number R_0 (and its value after initial disease emergence R) has long been used to predict the likelihood of pathogen invasion, to gauge the potential severity of an epidemic, and to set policy around interventions.…

Populations and Evolution · Quantitative Biology 2020-06-29 Clara L. Shaw , David A. Kennedy

The basic reproduction number ($R_0$) is a threshold parameter for disease extinction or survival in isolated populations. However no human population is fully isolated from other human or animal populations. We use compartmental models to…

Populations and Evolution · Quantitative Biology 2018-09-05 Angus McLure , Kathryn Glass

Branching processes are widely used to model evolutionary and population dynamics as well as the spread of infectious diseases. To characterize the dynamics of their growth or spread, the basic reproduction number $R_0$ has received…

Populations and Evolution · Quantitative Biology 2021-09-02 Johannes Pausch , Rosalba Garcia-Millan , Gunnar Pruessner

A general stochastic model for susceptible -> infective -> recovered (SIR) epidemics in non homogeneous populations is considered. The heterogeneity is a very important aspect here since it allows more realistic but also more complex…

Populations and Evolution · Quantitative Biology 2020-08-13 Zeynep Gökçe İşlier , Wolfgang Hörmann , Refik Güllü

A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…

Populations and Evolution · Quantitative Biology 2017-09-05 Kristoffer Spricer , Pieter Trapman

The basic and effective reproduction numbers are widely used metrics for characterizing the dynamics of infectious disease epidemics. However, the interpretation of these numbers is based on the assumption of homogeneous mixing and may not…

Populations and Evolution · Quantitative Biology 2026-03-24 Zahra Ghadiri , Jari Saramäki , Takayuki Hiraoka

Since the last century, deterministic compartmental models have emerged as powerful tools to predict and control epidemic outbreaks, in many cases helping to mitigate their impacts. A key quantity for these models is the so-called Basic…

Populations and Evolution · Quantitative Biology 2022-11-03 Àlex Giménez-Romero , Rosa Flaquer-Galmés , Manuel A. Matias

Structured epidemic models can be formulated as first-order hyperbolic PDEs, where the "spatial" variables represent individual traits, called structures. For models with two structures, we propose a numerical technique to approximate…

Numerical Analysis · Mathematics 2021-09-08 Dimitri Breda , Simone De Reggi , Francesca Scarabel , Rossana Vermiglio , Jianhong Wu

When an infectious disease strikes a population, the number of newly reported cases is often the only available information that one can obtain during early stages of the outbreak. An important goal of early outbreak analysis is to obtain a…

Quantitative Methods · Quantitative Biology 2013-05-30 Bahman Davoudi , Babak Pourbohloul , Joel Miller , Rafael Meza , Lauren Ancel Meyers , David J. D. Earn

Identifying the main environmental drivers of SARS-CoV-2 transmissibility in the population is crucial for understanding current and potential future outbursts of COVID-19 and other infectious diseases. To address this problem, we…

Populations and Evolution · Quantitative Biology 2021-09-01 Marko Djordjevic , Igor Salom , Sofija Markovic , Andjela Rodic , Ognjen Milicevic , Magdalena Djordjevic

In epidemiological modelings, the spectral radius of the next generation matrix evaluated at the trivial equilibrium was considered as the basic reproduction number. Also, the global stability of the trivial equilibrium point was determined…

Populations and Evolution · Quantitative Biology 2020-06-15 Hyun Mo Yang

An approach to estimate the influence of the treatment-type controls on the basic reproduction number, R 0 , is proposed and elaborated. The presented approach allows one to estimate the effect of a given treatment strategy or to compare a…

Populations and Evolution · Quantitative Biology 2023-05-30 Dmitry Gromov , Ingo Bulla , Ethan Obie Romero-Severson

This paper proposes a structural econometric approach to estimating the basic reproduction number ($\mathcal{R}_{0}$) of Covid-19. This approach identifies $\mathcal{R}_{0}$ in a panel regression model by filtering out the effects of…

Econometrics · Economics 2023-09-19 Ida Johnsson , M. Hashem Pesaran , Cynthia Fan Yang

Studies about epidemic modelling have been conducted since before 19th century. Both deterministic and stochastiic model were used to capture the dynamic of infection in the population. The purpose of this project is to investigate the…

Populations and Evolution · Quantitative Biology 2018-03-06 Kurnia Susvitasari

We study a multitype SIR epidemic model where individuals are categorized into different types, and where infection spread is characterized by a next-generation matrix $M=\{m_{ij}\}$ with community fractions $\{\pi_j\}$ for the different…

Populations and Evolution · Quantitative Biology 2026-03-10 Andrea Bizzotto , Frank Ball , Tom Britton

Vector-borne diseases with reservoir cycles are complex to understand because new infections come from contacts of the vector with humans and different reservoirs. In this scenario, the basic reproductive number $\mathcal{R}^h_0$ of the…

Populations and Evolution · Quantitative Biology 2017-02-10 Esteban Vargas , Camilo Sanabria

The effect of diffusion rates on the basic reproduction number of a general compartmental reaction-diffusion epidemic model in a heterogeneous environment is considered. It is shown when the diffusion rates tend to zero, the limit of the…

Dynamical Systems · Mathematics 2019-09-24 Shanshan Chen , Junping Shi