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We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

Populations and Evolution · Quantitative Biology 2021-08-17 Evangelos F. Magirou

We model further development of the COVID-19 epidemic in the UK given the current data and assuming different scenarios of handling the epidemic. In this research, we further extend the stochastic model suggested in \cite{us} and…

Populations and Evolution · Quantitative Biology 2020-04-10 Anatoly Zhigljavsky , Roger Whitaker , Ivan Fesenko , Kobi Kremnizer , Jack Noonan

The effective use of limited resources for controlling spreading processes on networks is of prime significance in diverse contexts, ranging from the identification of "influential spreaders" for maximizing information dissemination and…

Social and Information Networks · Computer Science 2022-06-01 Andrey Y. Lokhov , David Saad

This paper investigates the spread of infectious diseases within a networked community by integrating epidemic transmission and public opinion dynamics. We propose a novel discrete-time networked SIS (Susceptible-Infectious-Susceptible)…

Systems and Control · Electrical Eng. & Systems 2025-08-14 Qiulin Xu , Tatsuya Masada , Hideaki Ishii

Controlling and understanding epidemic outbreaks has recently drawn great interest in a large spectrum of research communities. Vaccination is one of the most well-established and effective strategies in order to contain an epidemic. In the…

Social and Information Networks · Computer Science 2023-05-29 Sourin Chatterjee , Ahad N. Zehmakan

Mathematical modeling of epidemic propagation on networks is extended to hypergraphs in order to account for both the community structure and the nonlinear dependence of the infection pressure on the number of infected neighbours. The exact…

Dynamical Systems · Mathematics 2016-10-31 Ágnes Bodó , Gyula Y. Katona , Péter L. Simon

Epidemics of infectious diseases posing a serious risk to human health have occurred throughout history. During recent epidemics there has been much debate about policy, including how and when to impose restrictions on behaviour.…

Theoretical Economics · Economics 2024-04-08 Simon K. Schnyder , John J. Molina , Ryoichi Yamamoto , Matthew S. Turner

Simulations of infectious disease spread have long been used to understand how epidemics evolve and how to effectively treat them. However, comparatively little attention has been paid to understanding the fairness implications of different…

Social and Information Networks · Computer Science 2019-11-14 James Atwood , Hansa Srinivasan , Yoni Halpern , D Sculley

Efficient allocation of limited medical resources is crucial for controlling epidemic spreading on networks. Based on the susceptible-infected-susceptible model, we solve an optimization problem as how best to allocate the limited resources…

Populations and Evolution · Quantitative Biology 2017-08-02 Hanshuang Chen , Guofeng Li , Haifeng Zhang , Zhonghuai Hou

After the COVID-19 pandemic, we saw an increase in demand for epidemiological mathematical models. The goal of this work is to study the optimal control for an age-structured model as a strategy of quarantine of infected people, which is…

Optimization and Control · Mathematics 2024-11-04 Nelson L. Santos Junior , João A. M. Gondim

In real social networks, person-to-person interactions are known to be heterogeneous, which can affect the way a disease spreads through a population, reaches a tipping point in the fraction of infected individuals, and becomes an epidemic.…

Physics and Society · Physics 2020-05-12 Ignacio A. Perez , Paul A. Trunfio , Cristian E. La Rocca , Lidia A. Braunstein

The COVID-19 pandemic and the mitigation policies implemented in response to it have resulted in economic losses worldwide. Attempts to understand the relationship between economics and epidemiology has lead to a new generation of…

In this work, we simulate the COVID-19 pandemic dynamics in a population modeled as a network of groups wherein infection can propagate both via intra-group and via inter-group interactions. Our results emphasize the importance of…

Physics and Society · Physics 2020-12-24 Ioan Baldea

The relationship between epidemiology, mathematical modeling and computational tools allows to build and test theories on the development and battling of a disease. This PhD thesis is motivated by the study of epidemiological models applied…

Optimization and Control · Mathematics 2014-01-30 Helena Sofia Rodrigues

While many efforts are currently devoted to vaccines development and administration, social distancing measures, including severe restrictions such as lockdowns, remain fundamental tools to contain the spread of COVID-19. A crucial point…

Systems and Control · Electrical Eng. & Systems 2021-09-03 Mauro Bisiacco , Gianluigi Pillonetto

Optimal control problems reflecting the finding of effective quarantine strategies are considered for two control SEIR~type models describing the spread of the COVID-19 virus in the human population. The properties of the corresponding…

Optimization and Control · Mathematics 2020-11-30 Ellina Grigorieva , Evgenii Khailov , Andrei Korobeinikov

In December 2019, the first patients in Wuhan, China were diagnosed with a primary atypical pneumonia, which showed to be unknown and contagious. Since then, known as COVID-19 disease, the responsible viral pathogen, SARS-CoV-2, has spread…

Populations and Evolution · Quantitative Biology 2024-01-30 Philipp Heider

Motivated by fundamental issues in non-equilibrium statistical mechanics (NESM), we study the venerable susceptible-infected (SIS) model of disease spreading in an idealized, simple setting. Using Monte Carlo and analytic techniques, we…

Statistical Mechanics · Physics 2015-06-22 Maxim S. Shkarayev , R. K. P. Zia

We analyze an epidemic model on a network consisting of susceptible-infected-recovered equations at the nodes coupled by diffusion using a graph Laplacian. We introduce an epidemic criterion and examine different vaccination/containment…

Physics and Society · Physics 2020-09-25 F. Bustamante-Castaneda , J. -G. Caputo , G. Cruz-Pacheco , A. Knippel , F. Mouatamide

Testing is a crucial control mechanism for an epidemic outbreak because it enables the health authority to detect and isolate the infected cases, thereby limiting the disease transmission to susceptible people, when no effective treatment…

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