Related papers: A novel range telescope concept for proton CT
To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…
Ion beam therapy has become a frequently applied form of cancer therapy over the last years. The advantage of ion beam therapy over conventional radiotherapy using photons is the strongly localized dose deposition, leading to a reduction of…
Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…
Laser acceleration promises innovation in particle beam therapy of cancer where an ultra-compact accelerator system for cancer beam therapy can become affordable to a broad range of patients. This is not feasible without the introduction of…
Physical and biological range uncertainties limit the clinical potential of Proton Beam Therapy (PBT). In this proceedings, we report on two research projects, which we are conducting in parallel and which both tackle the problem of range…
Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…
Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…
Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…
Treating cancer is one of the most challenging task in medical sciences. Only limited types of cancer treatments are available as their study is still ongoing. The earlier therapies like radiotherapy with x-rays, chemotherapy are associated…
Fast procedures for the beam quality assessment and for the monitoring of beam energy modulations during the irradiation are among the most urgent improvements in particle therapy. Indeed, the online measurement of the particle beam energy…
Objective. The objective of the presented study was to evaluate the feasibility of a coded-mask (CM) gamma camera for real-time range verification in proton therapy, addressing the need for a precise and efficient method of treatment…
Stereotactic body radiation therapy (SBRT) and hypofractionation using pencil-beam scanning (PBS) proton therapy (PBSPT) is an attractive option for thoracic malignancies. Combining the advantages of target coverage conformity and critical…
The design, construction, and preliminary testing of a second generation proton CT scanner is presented. All current treatment planning systems at proton therapy centers use X-ray CT as the primary imaging modality for treatment planning to…
Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…
Background and Objective: Recent experimental studies using ultra-high dose rate radiation therapy (FLASH-RT) have shown improved normal tissue sparing and comparable tumor control compared to conventional dose rate RT. Pencil beam scanning…
This report presents a design of a gantry for proton therapy based on the concept of adiabatic transition. The use of fixed-field alternating gradient magnets allows a large momentum acceptance and supports fast energy modulation. The…
The determination of relative stopping power (RSP) via proton computed tomography (pCT) of a patient is dependent in part on the knowledge of the incoming proton kinetic energies; the uncertainty in these energies is in turn determined by…
Proton Computed Tomography (pCT) provides a promising solution to enhance the accuracy of Relative Stopping Power (RSP) required for proton therapy planning. This research introduces a novel high-granularity pCT architecture that…
Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…
Proton therapy's full potential is limited by uncertainties that prevent optimal dose distribution. Monitoring techniques can reduce these uncertainties and enable adaptive treatment planning. Spatiotemporal Emission Reconstruction from…