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Lasers based on biological materials are attracting an increasing interest in view of their use in integrated and transient photonics. DNA as optical biopolymer in combination with highly-emissive dyes has been reported to have excellent…

Explosive growth in the amount of genomic data is matched by increasing power of consumer-grade computers. Even applications that require powerful servers can be quickly tested on desktop or laptop machines if we can generate representative…

Genomics · Quantitative Biology 2017-11-20 Anthony J. Greenberg

When an individual's DNA is sequenced, sensitive medical information becomes available to the sequencing laboratory. A recently proposed way to hide an individual's genetic information is to mix in DNA samples of other individuals. We…

Information Theory · Computer Science 2024-11-05 Kayvon Mazooji , Roy Dong , Ilan Shomorony

The problem of storing large amounts of information safely for a long period of time has become essential. One of the most promising new data storage mediums are the polymer-based data storage systems, like the DNA-storage system. These…

Information Theory · Computer Science 2025-04-21 Ville Junnila , Tero Laihonen , Tuomo Lehtilä

Synthetic DNA can in principle be used for the archival storage of arbitrary data. Because errors are introduced during DNA synthesis, storage, and sequencing, an error-correcting code (ECC) is necessary for error-free recovery of the data.…

Quantitative Methods · Quantitative Biology 2018-12-05 William H. Press , John A. Hawkins

With the rapidly changing technological realm, there is an urgent need to provide and protect the confidentiality of confidential images when stored in a cloud environment. To overcome the security risks associated with single cloud,…

Cryptography and Security · Computer Science 2016-11-24 Dr. Grasha Jacob , Dr. A. Murugan

We propose a novel coding scheme for DNA-based storage systems, called the shift-interleave (SI) coding, designed to correct insertion, deletion, and substitution (IDS) errors, as well as sequence losses. The SI coding scheme employs…

Information Theory · Computer Science 2024-01-29 Ryo Shibata , Haruhiko Kaneko

In order to accommodate the ever-growing data from various, possibly independent, sources and the dynamic nature of data usage rates in practical applications, modern cloud data storage systems are required to be scalable, flexible, and…

Information Theory · Computer Science 2020-09-22 Siyi Yang , Ahmed Hareedy , Robert Calderbank , Lara Dolecek

DNA data storage is rapidly emerging as a promising solution for long-term data archiving, largely due to its exceptional durability. However, the synthesis of DNA strands remains a significant bottleneck in terms of cost and speed. To…

Other Computer Science · Computer Science 2025-07-11 Parv Agarwal , Nimesh Pinnamaneni , Thomas Heinis

DNA sequences encode critical genetic information, yet their variable length and discrete nature impede direct utilization in deep learning models. Existing DNA representation schemes convert sequences into numerical vectors but fail to…

Genomics · Quantitative Biology 2025-12-16 Zhiyuan Peng , Naifan Zhang , Yuanbo Tang , Yang Li

DNA synthesis is considered as one of the most expensive components in current DNA storage systems. In this paper, focusing on a common synthesis machine, which generates multiple DNA strands in parallel following a fixed supersequence,we…

Information Theory · Computer Science 2025-05-13 Yajuan Liu , Tolga M. Duman

DNA storage has emerged as a promising solution for large-scale and long-term data preservation. Among various error types, insertions are the most frequent errors occurring in DNA sequences, where the inserted symbol is often identical or…

Information Theory · Computer Science 2026-04-07 Hengfeng Liu , Chunming Tang , Cuiling Fan

Powerful yet complex deep neural networks (DNNs) have fueled a booming demand for efficient DNN solutions to bring DNN-powered intelligence into numerous applications. Jointly optimizing the networks and their accelerators are promising in…

Machine Learning · Computer Science 2025-01-07 Yongan Zhang , Yonggan Fu , Weiwen Jiang , Chaojian Li , Haoran You , Meng Li , Vikas Chandra , Yingyan Celine Lin

In this paper we study error-correcting codes for the storage of data in synthetic deoxyribonucleic acid (DNA). We investigate a storage model where a data set is represented by an unordered set of $M$ sequences, each of length $L$. Errors…

Information Theory · Computer Science 2020-02-13 Andreas Lenz , Paul H. Siegel , Antonia Wachter-Zeh , Eitan Yaakobi

As DNA data storage moves closer to practical deployment, minimizing sequencing coverage depth is essential to reduce both operational costs and retrieval latency. This paper addresses the recently studied Random Access Problem, which…

Information Theory · Computer Science 2026-01-13 Chen Wang , Eitan Yaakobi

Over the past few years, deep neural networks (DNNs) have been continuously expanding their real-world applications for source code processing tasks across the software engineering domain, e.g., clone detection, code search, comment…

Software Engineering · Computer Science 2021-01-21 Maryam Vahdat Pour , Zhuo Li , Lei Ma , Hadi Hemmati

Data loading can dominate deep neural network training time on large-scale systems. We present a comprehensive study on accelerating data loading performance in large-scale distributed training. We first identify performance and scalability…

Machine Learning · Computer Science 2020-02-20 Chih-Chieh Yang , Guojing Cong

DNA is not only the genetic material of life, but also a favorable material for a new computing model. Various research works based on DNA computing have been carried out in recent years. DNA sequence design is the foundation of such…

Emerging Technologies · Computer Science 2023-11-10 Yao Yao , Xun Zhang , Xin Liu , Yuan Liu , Xiaokang Zhang , Qiang Zhang

Composite DNA is a recent method to increase the base alphabet size in DNA-based data storage.This paper models synthesizing and sequencing of composite DNA and introduces coding techniques to correct substitutions, losses of entire…

Information Theory · Computer Science 2025-10-29 Frederik Walter , Omer Sabary , Antonia Wachter-Zeh , Eitan Yaakobi

Deep neural networks (DNNs) have been widely deployed across diverse domains such as computer vision and natural language processing. However, the impressive accomplishments of DNNs have been realized alongside extensive computational…

Machine Learning · Computer Science 2023-11-28 Chuangtao Chen , Grace Li Zhang , Xunzhao Yin , Cheng Zhuo , Ulf Schlichtmann , Bing Li