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Motivation: High-coverage sequencing data have significant, yet hard to exploit, redundancy. Most FASTQ compressors cannot efficiently compress the DNA stream of large datasets, since the redundancy between overlapping reads cannot be…

Data Structures and Algorithms · Computer Science 2014-09-19 Szymon Grabowski , Sebastian Deorowicz , Łukasz Roguski

The DNA sequencing is the process of identifying the exact order of nucleotides within a given DNA molecule. The new portable and relatively inexpensive DNA sequencers, such as Oxford Nanopore MinION, have the potential to move DNA…

Computational Engineering, Finance, and Science · Computer Science 2019-01-09 Steven Y. Ko , Lauren Sassoubre , Jaroslaw Zola

The coverage depth problem in DNA data storage is about computing the expected number of reads needed to recover all encoded strands. Given a generator matrix of a linear code, this quantity equals the expected number of randomly drawn…

Information Theory · Computer Science 2026-03-09 Matteo Bertuzzo , Alberto Ravagnani , Eitan Yaakobi

Biological cells can transmit, process and receive chemically encoded data in the same way as network devices transmit, process, and receive digitally encoded data. Communication protocols have led to the rapid development of computer…

Other Computer Science · Computer Science 2019-08-22 A. M. El-Edkawy , M. A. El-Dosuky , Taher Hamza

As long as human beings exist on this earth, there will be confidential images intended for limited audience. These images have to be transmitted in such a way that no unauthorized person gets knowledge of them. DNA sequences play a vital…

Cryptography and Security · Computer Science 2016-11-28 Grasha Jacob , A. Murugan

To store information at extremely high-density and data-rate, we propose to adapt, integrate, and extend the techniques developed by chemists and molecular biologists for the purpose of manipulating biological and other macromolecules. In…

Emerging Technologies · Computer Science 2017-08-29 M. Mansuripur , P. K. Khulbe , S. M. Kuebler , J. W. Perry , M. S. Giridhar , J. Kevin Erwin , Kibyung Seong , Seth Marder , N. Peyghambarian

DNA codes have many applications, such as in data storage, DNA computing, etc. Good DNA codes have large sizes and satisfy some certain constraints. In this paper, we present a new construction method for reversible DNA codes. We show that…

Information Theory · Computer Science 2024-03-19 Xueyan Chen , Whan-Hyuk Choi , Hongwei Liu

DNA-based storage has emerged as a promising approach to the global data crisis, offering molecular-scale density and millennial-scale stability at low maintenance cost. Over the past decade, substantial progress has been made in storing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Cihan Ruan , Lebin Zhou , Bingqing Zhao , Rongduo Han , Qiming Yuan , Chenchen Zhu , Linyi Han , Liang Yang , Wei Wang , Wei Jiang , Nam Ling

Deep Neural Networks (DNNs) are a revolutionary force in the ongoing information revolution, and yet their intrinsic properties remain a mystery. In particular, it is widely known that DNNs are highly sensitive to noise, whether adversarial…

Machine Learning · Computer Science 2020-05-01 Netanel Raviv , Siddharth Jain , Pulakesh Upadhyaya , Jehoshua Bruck , Anxiao Jiang

With recent high-throughput technology we can synthesize large heterogeneous collections of DNA structures, and also read them all out precisely in a single procedure. Can we use these tools, not only to do things faster, but also to devise…

Data Structures and Algorithms · Computer Science 2021-12-07 Luca Cardelli

Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

This paper proposes a framework for distributed, in-storage training of neural networks on clusters of computational storage devices. Such devices not only contain hardware accelerators but also eliminate data movement between the host and…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-14 Ali HeydariGorji , Mahdi Torabzadehkashi , Siavash Rezaei , Hossein Bobarshad , Vladimir Alves , Pai H. Chou

Storing data in DNA is being explored as an efficient solution for archiving and in-object storage. Synthesis time and cost remain challenging, significantly limiting some applications at this stage. In this paper we investigate efficient…

Information Theory · Computer Science 2024-12-10 Amit Zrihan , Eitan Yaakobi , Zohar Yakhini

Data hiding is essential for secure communication across digital media, and recent advances in Deep Neural Networks (DNNs) provide enhanced methods for embedding secret information effectively. However, previous audio hiding methods often…

Sound · Computer Science 2025-10-06 Wei Fan , Kejiang Chen , Xiangkun Wang , Weiming Zhang , Nenghai Yu

Deep neural networks (DNNs) have proven to be quite effective in a vast array of machine learning tasks, with recent examples in cyber security and autonomous vehicles. Despite the superior performance of DNNs in these applications, it has…

Machine Learning · Computer Science 2017-08-22 Qinglong Wang , Wenbo Guo , Kaixuan Zhang , Alexander G. Ororbia , Xinyu Xing , Xue Liu , C. Lee Giles

We consider the problem of assembling a sequence based on a collection of its substrings observed through a noisy channel. The mathematical basis of the problem is the construction and design of sequences that may be discriminated based on…

Information Theory · Computer Science 2015-11-04 Han Mao Kiah , Gregory J. Puleo , Olgica Milenkovic

The distributed edge storage system can store data collected at the edge of the network in a decentralised manner, with low latency, high security, and flexibility. Traditional edge-distributed storage systems only consider one single…

Networking and Internet Architecture · Computer Science 2023-10-10 Yejin Yang , Miao Ye , Qiuxiang Jiang , Peng Wen

With the advancement in technology, digital images can easily be transmitted and stored over the Internet. Encryption is used to avoid illegal interception of digital images. Encrypting large-sized colour images in their original dimension…

Supervised learning on Deep Neural Networks (DNNs) is data hungry. Optimizing performance of DNN in the presence of noisy labels has become of paramount importance since collecting a large dataset will usually bring in noisy labels.…

Computer Vision and Pattern Recognition · Computer Science 2020-12-09 Shuyu Kong , You Li , Jia Wang , Amin Rezaei , Hai Zhou

In this paper, we study the Random Access Problem in DNA storage, which addresses the challenge of retrieving a specific information strand from a DNA-based storage system. In this framework, the data is represented by $k$ information…

Information Theory · Computer Science 2025-08-26 Avital Boruchovsky , Ohad Elishco , Ryan Gabrys , Anina Gruica , Itzhak Tamo , Eitan Yaakobi
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