English

Coding for Composite DNA to Correct Substitutions, Strand Losses, and Deletions

Information Theory 2025-10-29 v1 math.IT

Abstract

Composite DNA is a recent method to increase the base alphabet size in DNA-based data storage.This paper models synthesizing and sequencing of composite DNA and introduces coding techniques to correct substitutions, losses of entire strands, and symbol deletion errors. Non-asymptotic upper bounds on the size of codes with tt occurrences of these error types are derived. Explicit constructions are presented which can achieve the bounds.

Keywords

Cite

@article{arxiv.2404.12868,
  title  = {Coding for Composite DNA to Correct Substitutions, Strand Losses, and Deletions},
  author = {Frederik Walter and Omer Sabary and Antonia Wachter-Zeh and Eitan Yaakobi},
  journal= {arXiv preprint arXiv:2404.12868},
  year   = {2025}
}
R2 v1 2026-06-28T15:59:48.813Z