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Deep convolutional neural networks (DCNN) have demonstrated its capability to convert MR image to pseudo CT for PET attenuation correction in PET/MRI. Conventionally, attenuated events are corrected in sinogram space using attenuation maps…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Jaewon Yang , Dookun Park , Jae Ho Sohn , Zhen Jane Wang , Grant T. Gullberg , Youngho Seo

Attenuation and scatter correction (AC) is crucial for quantitative Positron Emission Tomography (PET) imaging. Recently, direct application of AC in the image domain using deep learning approaches has been proposed for the hybrid PET/MR…

Medical Physics · Physics 2022-06-30 Reza Jahangir , Alireza Kamali-Asl , Hossein Arabi

High noise and low spatial resolution are two key confounding factors that limit the qualitative and quantitative accuracy of PET images. AI models for image denoising and deblurring are becoming increasingly popular for post-reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Juan Liu , Masoud Malekzadeh , Niloufar Mirian , Tzu-An Song , Chi Liu , Joyita Dutta

Artificial intelligence (AI) has significant potential to positively impact and advance medical imaging, including positron emission tomography (PET) imaging applications. AI has the ability to enhance and optimize all aspects of the PET…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Arkadiusz Sitek , Sangtae Ahn , Evren Asma , Adam Chandler , Alvin Ihsani , Sven Prevrhal , Arman Rahmim , Babak Saboury , Kris Thielemans

Attenuation compensation (AC) is a pre-requisite for reliable quantification and beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT). Typical AC methods require the availability of an attenuation…

Medical Physics · Physics 2021-02-12 Zitong Yu , Md Ashequr Rahman , Thomas Schindler , Richard Laforest , Abhinav K. Jha

LAFOV PET/CT has the potential to unlock new applications such as ultra-low dose PET/CT imaging, multiplexed imaging, for biomarker development and for faster AI-driven reconstruction, but further work is required before these can be…

Recently, spectral CT has been drawing a lot of attention in a variety of clinical applications primarily due to its capability of providing quantitative information about material properties. The quantitative integrity of the reconstructed…

Medical Physics · Physics 2018-01-12 Shiyu Xu , Peter Prinsen , Jens Wiegert , Ravindra Manjeshwar

Photon attenuation and scatter are the two main physical factors affecting the diagnostic quality of SPECT in its applications in brain imaging. In this work, we present a novel Bayesian Optimization approach for Attenuation Correction…

Medical Physics · Physics 2021-09-27 Loizos Koutsantonis , Ayman Makki , Tiago Carneiro , Emmanuel Kieffer , Pascal Bouvry

Artificial intelligence (AI) is being deployed within radiology at a rapid pace. AI has proven an excellent tool for reconstructing and enhancing images that appear sharper, smoother, and more detailed, can be acquired more quickly, and…

Artificial Intelligence · Computer Science 2026-02-11 Jana G. Delfino , Jason L. Granstedt , Frank W. Samuelson , Robert Ochs , Krishna Juluru

Artificial intelligence (AI) techniques for image-based segmentation have garnered much attention in recent years. Convolutional neural networks (CNNs) have shown impressive results and potential towards fully automated segmentation in…

Medical Physics · Physics 2021-11-17 Fereshteh Yousefirizi , Abhinav K. Jha , Julia Brosch-Lenz , Babak Saboury , Arman Rahmim

This paper reviewed the machine learning-based studies for quantitative positron emission tomography (PET). Specifically, we summarized the recent developments of machine learning-based methods in PET attenuation correction and low-count…

Image and Video Processing · Electrical Eng. & Systems 2020-01-22 Tonghe Wang , Yang Lei , Yabo Fu , Walter J. Curran , Tian Liu , Xiaofeng Yang

Reliable attenuation and scatter compensation (ASC) is a prerequisite for quantification and beneficial for visual interpretation tasks in SPECT. In this paper, we develop a reconstruction method that uses the entire SPECT emission data,…

Medical Physics · Physics 2020-03-02 Md Ashequr Rahman , Richard Laforest , Abhinav K. Jha

Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

This paper provides a fast and patient-specific scatter artifact correction method for cone-beam computed tomography (CBCT) used in image-guided interventional procedures. Due to increased irradiated volume of interest in CBCT imaging,…

Medical Physics · Physics 2015-01-20 Wei Zhao , Stephen Brunner , Kai Niu , Sebastian Schafer , Kevin Royalty , Guang-Hong Chen

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

Efficiently acquired and precisely reconstructed imaging are crucial to the success of modern radiation therapy (RT). Computed tomography (CT) and magnetic resonance imaging (MRI) are two common modalities for providing RT treatment…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Di Xu

The influence of artificial intelligence (AI) within the field of nuclear medicine has been rapidly growing. Many researchers and clinicians are seeking to apply AI within PET, and clinicians will soon find themselves engaging with AI-based…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Tyler J. Bradshaw , Alan B. McMillan

Scattered coincidences introduce quantitative bias in positron emission tomography (PET) and must be compensated during reconstruction. Conventional scatter estimates typically rely on simplified cylindrical scanner models that omit…

Due to its wide field of view, cone-beam computed tomography (CBCT) is plagued by large amounts of scatter, where attenuated photons hit the detector, and corrupt the linear models used for reconstruction. Given that one can generate a good…

Medical Physics · Physics 2017-07-06 Jonathan Mason , Alessandro Perelli , William Nailon , Mike Davies
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