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Identifying cohorts of patients based on eligibility criteria such as medical conditions, procedures, and medication use is critical to recruitment for clinical trials. Such criteria are often most naturally described in free-text, using…
A large percentage of medical information is in unstructured text format in electronic medical record systems. Manual extraction of information from clinical notes is extremely time consuming. Natural language processing has been widely…
Colorectal cancer (CRC), a lethal disease, begins with the growth of abnormal mucosal cell proliferation called polyps in the inner wall of the colon. When left undetected, polyps can become malignant tumors. Colonoscopy is the standard…
Chemotherapy for cancer treatment is costly and accompanied by severe side effects, highlighting the critical need for early prediction of treatment outcomes to improve patient management and informed decision-making. Predictive models for…
Brain functional connectivity (FC) extracted from resting-state fMRI (RS-fMRI) has become a popular approach for disease diagnosis, where discriminating subjects with mild cognitive impairment (MCI) from normal controls (NC) is still one of…
Lung and colon cancer are serious worldwide health challenges that require early and precise identification to reduce mortality risks. However, diagnosis, which is mostly dependent on histopathologists' competence, presents difficulties and…
PURPOSE: This study aimed to develop a deep learning-based tool to detect and localize lung nodules with chest radiographs(CXRs). We expected it to enhance the efficiency of interpreting CXRs and reduce the possibilities of delayed…
Microscopic examination of tissues or histopathology is one of the diagnostic procedures for detecting colorectal cancer. The pathologist involved in such an examination usually identifies tissue type based on texture analysis, especially…
Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…
Traditional diagnostic methods like colonoscopy are invasive yet critical tools necessary for accurately diagnosing colorectal cancer (CRC). Detection of CRC at early stages is crucial for increasing patient survival rates. However,…
Accurate prediction of recurrence in clear cell renal cell carcinoma (ccRCC) remains a major clinical challenge due to the disease complex molecular, pathological, and clinical heterogeneity. Traditional prognostic models, which rely on…
A language model can be used to predict the next word during authoring, to correct spelling or to accelerate writing (e.g., in sms or emails). Language models, however, have only been applied in a very small scale to assist physicians…
Digital histology images are amenable to the application of convolutional neural network (CNN) for analysis due to the sheer size of pixel data present in them. CNNs are generally used for representation learning from small image patches…
Machine learning methods have recently achieved high-performance in biomedical text analysis. However, a major bottleneck in the widespread application of these methods is obtaining the required large amounts of annotated training data,…
Benchmarking drug efficacy is a critical step in clinical trial design and planning. The challenge is that much of the data on efficacy endpoints is stored in scientific papers in free text form, so extraction of such data is currently a…
Colorectal cancer is a leading cause of death worldwide. However, early diagnosis dramatically increases the chances of survival, for which it is crucial to identify the tumor in the body. Since its imaging uses high-resolution techniques,…
Multimodal Large Language Models (MLLMs) have demonstrated remarkable potential in medical image analysis. However, their application in gastrointestinal endoscopy is currently hindered by two critical limitations: the misalignment between…
We introduce Med-CTX, a fully transformer based multimodal framework for explainable breast cancer ultrasound segmentation. We integrate clinical radiology reports to boost both performance and interpretability. Med-CTX achieves exact…
Medical image analysis requires substantial labeled data for model training, yet expert annotation is expensive and time-consuming. Active learning (AL) addresses this challenge by strategically selecting the most informative samples for…
The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…