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In many scenarios, especially biomedical applications, the correct delineation of complex fine-scaled structures such as neurons, tissues, and vessels is critical for downstream analysis. Despite the strong predictive power of deep learning…
This study introduces a novel unsupervised medical image feature extraction method that employs spatial stratification techniques. An objective function based on weight is proposed to achieve the purpose of fast image recognition. The…
As computer vision continues to advance and finds widespread applications across various domains, the need for interpretability in deep learning models becomes paramount. Existing methods often resort to post-hoc techniques or prototypes to…
Recently, deep convolutional neural networks have achieved great success for medical image segmentation. However, unlike segmentation of natural images, most medical images such as MRI and CT are volumetric data. In order to make full use…
Deep learning has been increasingly incorporated into various computational pathology applications to improve its efficiency, accuracy, and robustness. Although successful, most previous approaches for image classification have crucial…
Deep-neural-network-based image reconstruction has demonstrated promising performance in medical imaging for under-sampled and low-dose scenarios. However, it requires large amount of memory and extensive time for the training. It is…
Convolutional Neural Networks demonstrate high performance on ImageNet Large-Scale Visual Recognition Challenges contest. Nevertheless, the published results only show the overall performance for all image classes. There is no further…
Tilting planar samples for multi-zone-axes observation is a routine procedure in electron microscopy. However, this process invariably introduces optical path differences in the electron beam across different sample positions, significantly…
The problem of recognizing various types of tissues present in multi-gigapixel histology images is an important fundamental pre-requisite for downstream analysis of the tumor microenvironment in a bottom-up analysis paradigm for…
Convolutional neural networks are the way to solve arbitrary image segmentation tasks. However, when images are large, memory demands often exceed the available resources, in particular on a common GPU. Especially in biomedical imaging,…
This paper presents a novel unsupervised segmentation method for 3D medical images. Convolutional neural networks (CNNs) have brought significant advances in image segmentation. However, most of the recent methods rely on supervised…
Deep neural networks implement a sequence of layer-by-layer operations that are each relatively easy to understand, but the resulting overall computation is generally difficult to understand. We consider a simple hypothesis for interpreting…
Pattern extraction algorithms are enabling insights into the ever-growing amount of today's datasets by translating reoccurring data properties into compact representations. Yet, a practical problem arises: With increasing data volumes and…
Computational pathology (CPath) digitizes pathology slides into whole slide images (WSIs), enabling analysis for critical healthcare tasks such as cancer diagnosis and prognosis. However, WSIs possess extremely long sequence lengths (up to…
Deep convolutional neural networks (CNNs) have achieved breakthrough performance in many pattern recognition tasks such as image classification. However, the development of high-quality deep models typically relies on a substantial amount…
Computational pathology tasks have some unique characterises such as multi-gigapixel images, tedious and frequently uncertain annotations, and unavailability of large number of cases [13]. To address some of these issues, we present Deep…
Although deep convolutional neural networks (CNNs) have achieved great success in computer vision tasks, its real-world application is still impeded by its voracious demand of computational resources. Current works mostly seek to compress…
Topological structures in image data, such as connected components and loops, play a crucial role in understanding image content (e.g., biomedical objects). % Despite remarkable successes of numerous image processing methods that rely on…
Convolutional neural networks (CNN) have recently achieved state-of-the-art results in various applications. In the case of image recognition, an ideal model has to learn independently of the training data, both local dependencies between…
Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…