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The analysis of secondary quantitative data extracted from high-resolution synchrotron X-ray computed tomography scans represents a significant challenge for users. While a number of methods have been introduced for processing large…

Human-Computer Interaction · Computer Science 2025-05-16 Anja Heim , Thomas Lang , Christoph Heinzl

Recent years have seen significant efforts to adopt Artificial Intelligence (AI) in healthcare for various use cases, from computer-aided diagnosis to ICU triage. However, the size of AI models has been rapidly growing due to scaling laws…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Mohammed Adnan , Qinle Ba , Nazim Shaikh , Shivam Kalra , Satarupa Mukherjee , Auranuch Lorsakul

We propose a new model for digital pathology segmentation, based on the observation that histopathology images are inherently symmetric under rotation and reflection. Utilizing recent findings on rotation equivariant CNNs, the proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Bastiaan S. Veeling , Jasper Linmans , Jim Winkens , Taco Cohen , Max Welling

Pathology image segmentation is crucial in computational pathology for analyzing histological features relevant to cancer diagnosis and prognosis. However, current methods face major challenges in clinical applications due to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zhixuan Chen , Junlin Hou , Liqi Lin , Yihui Wang , Yequan Bie , Xi Wang , Yanning Zhou , Ronald Cheong Kin Chan , Hao Chen

Due to the complexity of the human body, most diseases present a high inter-personal variability in the way they manifest, i.e. in their phenotype, which has important clinical repercussions - as for instance the difficulty in defining…

Physics and Society · Physics 2018-06-06 Massimiliano Zanin , Juan Manuel Tuñas , Ernestina Menasalvas

Deep learning has recently gained popularity in digital pathology due to its high prediction quality. However, the medical domain requires explanation and insight for a better understanding beyond standard quantitative performance…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Miriam Hägele , Philipp Seegerer , Sebastian Lapuschkin , Michael Bockmayr , Wojciech Samek , Frederick Klauschen , Klaus-Robert Müller , Alexander Binder

In this survey paper, we review recent uses of convolution neural networks (CNNs) to solve inverse problems in imaging. It has recently become feasible to train deep CNNs on large databases of images, and they have shown outstanding…

Image and Video Processing · Electrical Eng. & Systems 2018-09-11 Michael T. McCann , Kyong Hwan Jin , Michael Unser

Image segmentation is crucial in many computational pathology pipelines, including accurate disease diagnosis, subtyping, outcome, and survivability prediction. The common approach for training a segmentation model relies on a pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Sachin Kumar Danisetty , Alexandros Graikos , Srikar Yellapragada , Dimitris Samaras

We present highly efficient algorithms for performing forward and backward propagation of Convolutional Neural Network (CNN) for pixelwise classification on images. For pixelwise classification tasks, such as image segmentation and object…

Computer Vision and Pattern Recognition · Computer Science 2014-12-17 Hongsheng Li , Rui Zhao , Xiaogang Wang

The realm of medical image diagnosis has advanced significantly with the integration of computer-aided diagnosis and surgical systems. However, challenges persist, particularly in achieving precise image segmentation. While deep learning…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Mutyyba Asghar , Ahmad Raza Shahid , Akhtar Jamil , Kiran Aftab , Syed Ather Enam

Convolutional Neural Networks (CNNs) are the state-of-the-art algorithms for the processing of images. However the configuration and training of these networks is a complex task requiring deep domain knowledge, experience and much trial and…

Computer Vision and Pattern Recognition · Computer Science 2021-02-11 Yaron Strauch , Jo Grundy

The combination of data analysis methods, increasing computing capacity, and improved sensors enable quantitative granular, multi-scale, cell-based analyses. We describe the rich set of application challenges related to tissue…

Artificial Intelligence · Computer Science 2022-06-16 Rajarsi Gupta , Jakub Kaczmarzyk , Soma Kobayashi , Tahsin Kurc , Joel Saltz

Prostate cancer is one of the most common causes of cancer deaths in men. There is a growing demand for noninvasively and accurately diagnostic methods that facilitate the current standard prostate cancer risk assessment in clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-12-30 Ping-Chang Lin , Teodora Szasz , Hakizumwami B. Runesha

Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Mohammed Adnan , Shivam Kalra , Hamid R. Tizhoosh

Convolutional neural networks (CNNs) are a standard tool for computer vision tasks such as image classification. However, typical model architectures may result in the loss of topological information. In specific domains such as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-05 Shrunal Pothagoni , Benjamin Schweinhart

Neural networks in the real domain have been studied for a long time and achieved promising results in many vision tasks for recent years. However, the extensions of the neural network models in other number fields and their potential…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Xuanyu Zhu , Yi Xu , Hongteng Xu , Changjian Chen

We present compositional nearest neighbors (CompNN), a simple approach to visually interpreting distributed representations learned by a convolutional neural network (CNN) for pixel-level tasks (e.g., image synthesis and segmentation). It…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Victor Fragoso , Chunhui Liu , Aayush Bansal , Deva Ramanan

We present a simple yet general and efficient approach to representation of computational meshes. Meshes are represented as sets of mesh entities of different topological dimensions and their incidence relations. We discuss a…

Numerical Analysis · Mathematics 2012-05-15 Anders Logg

Machine learning-based analysis of medical images often faces several hurdles, such as the lack of training data, the curse of dimensionality problem, and the generalization issues. One of the main difficulties is that there exists…

Machine Learning · Computer Science 2019-07-29 Chang Min Hyun , Kang Cheol Kim , Hyun Cheol Cho , Jae Kyu Choi , Jin Keun Seo

Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…

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