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Computer Tomography (CT) images have become quite important to diagnose diseases. CT scan slice contains a vast amount of data that may not be properly examined with the requisite precision and speed using normal visual inspection. A…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Md Moniruzzaman Emon , Tareque Rahman Ornob , Moqsadur Rahman

Tissue characterization has long been an important component of Computer Aided Diagnosis (CAD) systems for automatic lesion detection and further clinical planning. Motivated by the superior performance of deep learning methods on various…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Xiang Li , Aoxiao Zhong , Ming Lin , Ning Guo , Mu Sun , Arkadiusz Sitek , Jieping Ye , James Thrall , Quanzheng Li

In the past ten years, the computing power of machine vision (MV) has been continuously improved, and image analysis algorithms have developed rapidly. At the same time, histopathological slices can be stored as digital images. Therefore,…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Xiaoqi Li , Haoyuan Chen , Chen Li , Md Mamunur Rahaman , Xintong Li , Jian Wu , Xiaoyan Li , Hongzan Sun , Marcin Grzegorzek

There is a limitation in the size of an image that can be processed using computationally demanding methods such as e.g. Convolutional Neural Networks (CNNs). Some imaging modalities - notably biological and medical - can result in images…

Image and Video Processing · Electrical Eng. & Systems 2020-07-01 Nicolas Pielawski , Carolina Wählby

Recent advancements in deep learning for automated image processing and classification have accelerated many new applications for medical image analysis. However, most deep learning applications have been developed using reconstructed,…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Hyunkwang Lee , Chao Huang , Sehyo Yune , Shahein H. Tajmir , Myeongchan Kim , Synho Do

An optical microscopic examination of thinly cut stained tissue on glass slides prepared from a FFPE tissue blocks is the gold standard for tissue diagnostics. In addition, the diagnostic abilities and expertise of any pathologist is…

Modern deep neural networks have shown remarkable performance in medical image classification. However, such networks either emphasize pixel-intensity features instead of fundamental anatomical structures (e.g., those encoded by topological…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Pengfei Gu , Huimin Li , Haoteng Tang , Dongkuan , Xu , Erik Enriquez , DongChul Kim , Bin Fu , Danny Z. Chen

Deep learning has driven significant advances in medical image analysis, yet its adoption in clinical practice remains constrained by the large size and lack of transparency in modern models. Advances in interpretability techniques such as…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Nikita Malik , Pratinav Seth , Neeraj Kumar Singh , Chintan Chitroda , Vinay Kumar Sankarapu

In this paper, we introduce a new dataset, \textbf{Kimia Path24}, for image classification and retrieval in digital pathology. We use the whole scan images of 24 different tissue textures to generate 1,325 test patches of size…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Morteza Babaie , Shivam Kalra , Aditya Sriram , Christopher Mitcheltree , Shujin Zhu , Amin Khatami , Shahryar Rahnamayan , H. R. Tizhoosh

Skeletonization extracts thin representations from images that compactly encode their geometry and topology. These representations have become an important topological prior for preserving connectivity in curvilinear structures, aiding…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Luis D. Reyes Vargas , Martin J. Menten , Johannes C. Paetzold , Nassir Navab , Mohammad Farid Azampour

As many algorithms depend on a suitable representation of data, learning unique features is considered a crucial task. Although supervised techniques using deep neural networks have boosted the performance of representation learning, the…

Computer Vision and Pattern Recognition · Computer Science 2020-09-07 Milad Sikaroudi , Amir Safarpoor , Benyamin Ghojogh , Sobhan Shafiei , Mark Crowley , H. R. Tizhoosh

We explore the problem of classification within a medical image data-set based on a feature vector extracted from the deepest layer of pre-trained Convolution Neural Networks. We have used feature vectors from several pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2017-10-17 Brady Kieffer , Morteza Babaie , Shivam Kalra , H. R. Tizhoosh

Deep learning models are routinely employed in computational pathology (CPath) for solving problems of diagnostic and prognostic significance. Typically, the generalization performance of CPath models is analyzed using evaluation protocols…

Image and Video Processing · Electrical Eng. & Systems 2021-06-18 Alex Foote , Amina Asif , Ayesha Azam , Tim Marshall-Cox , Nasir Rajpoot , Fayyaz Minhas

This paper presents an autoencoder-based neural network architecture to compress histopathological images while retaining the denser and more meaningful representation of the original images. Current research into improving compression…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 Agnes Barsi , Suvendu Chandan Nayak , Sasmita Parida , Raj Mani Shukla

In this paper, we propose an end-to-end mixed-resolution image compression framework with convolutional neural networks. Firstly, given one input image, feature description neural network (FDNN) is used to generate a new representation of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-03 Lijun Zhao , Huihui Bai , Feng Li , Anhong Wang , Yao Zhao

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Flow-Imaging Microscopy (FIM) is commonly used in both academia and industry to characterize subvisible particles (those $\le 25 \mu m$ in size) in protein therapeutics. Pharmaceutical companies are required to record vast volumes of FIM…

Quantitative Methods · Quantitative Biology 2017-09-04 Christopher P. Calderon , Austin L. Daniels , Theodore W. Randolph

Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…

Computer Vision and Pattern Recognition · Computer Science 2018-10-02 Faisal Mahmood , Richard Chen , Sandra Sudarsky , Daphne Yu , Nicholas J. Durr

Analysis and manipulation of trained neural networks is a challenging and important problem. We propose a symbolic representation for piecewise-linear neural networks and discuss its efficient computation. With this representation, one can…

Machine Learning · Computer Science 2019-08-21 Matthew Sotoudeh , Aditya V. Thakur

The topic of semantic segmentation has witnessed considerable progress due to the powerful features learned by convolutional neural networks (CNNs). The current leading approaches for semantic segmentation exploit shape information by…

Computer Vision and Pattern Recognition · Computer Science 2016-11-18 Jifeng Dai , Kaiming He , Jian Sun