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We show that with spatially incoherent illumination, the point spread function width of an imaging interferometer like that used in full-field optical coherence tomography (FFOCT) is almost insensitive to aberrations that mostly induce a…

Optics · Physics 2016-08-16 Peng Xiao , Mathias Fink , A. Claude Boccara

Retinal Optical Coherence Tomography (OCT) segmentation is essential for diagnosing pathology. Traditional methods focus on either spatial or spectral domains, overlooking their combined dependencies. We propose a triple-encoder network…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Kristin Qi , Xinhan Di

We apply three optical coherence tomography (OCT) image analysis techniques to extract morphometric information from OCT images obtained on peripheral nerves of rat. The accuracy of each technique is evaluated against histological…

Tissues and Organs · Quantitative Biology 2019-01-09 J. Hope , B. Brauer , S. Amirapu , A. McDaid , F. Vanholsbeeck

Optical diffraction tomography (ODT) is a powerful non-invasive 3D imaging technique, but its combination with broadband light sources is difficult. In this study, we introduce ultrabroadband ODT, covering over 150 nm of visible spectral…

Optical Coherence Tomography Angiography (OCTA) is a non-invasive and non-contacting imaging technique providing visualization of microvasculature of retina and optic nerve head in human eyes in vivo. The adequate image quality of OCTA is…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Yufei Wang , Yiqing Shen , Meng Yuan , Jing Xu , Bin Yang , Chi Liu , Wenjia Cai , Weijing Cheng , Wei Wang

We demonstrate experimentally quantum-inspired, spectral-domain intensity optical coherence tomography. We show that the technique allows for both axial resolution improvement and dispersion cancellation compared to conventional optical…

Optics · Physics 2015-03-16 Piotr Ryczkowski , Jari Turunen , Ari T. Friberg , Goëry Genty

The emerging technique of mid-infrared optical coherence tomography (MIR-OCT) takes advantage of the reduced scattering of MIR light in various materials and devices, enabling tomographic imaging at deeper penetration depths. Because of…

Large-volume optical coherence tomography (OCT)-setups employ scanning mirrors and suffer from non-linear geometric distortion artifacts in which the degree of distortion is determined by the maximum angles over which the mirrors rotate. In…

Purpose. Localizing structures and estimating the motion of a specific target region are common problems for navigation during surgical interventions. Optical coherence tomography (OCT) is an imaging modality with a high spatial and…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Marcel Bengs , Nils Gessert , Matthias Schlüter , Alexander Schlaefer

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging technique that possesses great potential for a wide range of biomedical imaging applications. In OAT, a laser is employed to…

Medical Physics · Physics 2016-12-21 Yang Lou , Kun Wang , Alexander. A. Oraevsky , Mark. A. Anastasio

The optic nerve head represents the intraocular section of the optic nerve (ONH), which is prone to damage by intraocular pressure. The advent of optical coherence tomography (OCT) has enabled the evaluation of novel optic nerve head…

Automatic motion compensation and adjustment of an intraoperative imaging modality's field of view is a common problem during interventions. Optical coherence tomography (OCT) is an imaging modality which is used in interventions due to its…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Nils Gessert , Martin Gromniak , Matthias Schlüter , Alexander Schlaefer

Optical coherence tomography (OCT) is commonly used to analyze retinal layers for assessment of ocular diseases. In this paper, we propose a method for retinal layer segmentation and quantification of uncertainty based on Bayesian deep…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Suman Sedai , Bhavna Antony , Dwarikanath Mahapatra , Rahil Garnavi

Optical coherence tomography (OCT) is a prevalent non-invasive imaging method which provides high resolution volumetric visualization of retina. However, its inherent defect, the speckle noise, can seriously deteriorate the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Dewei Hu , Yuankai K. Tao , Ipek Oguz

Conventional Fourier-domain Optical Coherence Tomography (FD-OCT) systems depend on resampling into wavenumber (k) domain to extract the depth profile. This either necessitates additional hardware resources or amplifies the existing…

Optics · Physics 2025-09-24 Maryam Viqar , Erdem Sahin , Elena Stoykova , Violeta Madjarova

Dynamic optical coherence tomography (DOCT) enables label-free functional imaging by capturing temporal OCT signal variations caused by intracellular and intratissue motions. However, the relationship between DOCT signals and the sample…

In this work, we propose to leverage a deep-learning (DL) based reconstruction framework for high quality Swept-Source Optical Coherence Tomography (SS-OCT) images, by incorporating wavelength ({\lambda}) space interferometric fringes.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Maryam Viqar , Erdem Sahin , Violeta Madjarova , Elena Stoykova , Keehoon Hong

A robust model for simulating speckle pattern evolution in optical coherence tomography (OCT) depending on the OCT system parameters and tissue deformation is reported. The model is based on application of close to reality procedures used…

Medical Physics · Physics 2014-11-04 V. Yu. Zaitsev , L. A. Matveev , A. L. Matveyev , G. V. Gelikonov , V. M. Gelikonov

Fiber-form optics extends the high-resolution tomographic imaging capabilities of Optical Coherence Tomography (OCT) to the inside of the human body, i.e., endoscopic OCT. However, it still faces challenges due to the trade-off between…

Optics · Physics 2024-09-04 Chengfu Gu , Haoran Zhang , Qi Lan , Weiyi Zhang , Chang Liu , Jianlong Yang

Optical diffraction tomography (ODT) has emerged as an important label-free tool in biomedicine to measure the three-dimensional (3D) structure of a biological sample. In this paper, we describe ODT using second-harmonic generation (SHG)…

Optics · Physics 2024-05-21 Amirhossein Saba , Carlo Gigli , Ye Pu , Demetri Psaltis