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We present a method for logical specification of the behavior of a system based on the specification of its components and for representing and specifying the effect of a class of communication "signaling pathways" among them. Variations in…

Other Quantitative Biology · Quantitative Biology 2019-09-09 Leo Marcus

Retrosynthesis is the task of breaking down a chemical compound recursively step-by-step into molecular precursors until a set of commercially available molecules is found. Consequently, the goal is to provide a valid synthesis route for a…

Cell biasing and downlink transmit power are two controls that may be used to improve the spectral efficiency of cellular networks. With cell biasing, each mobile user associates with the base station offering, say, the highest biased…

Information Theory · Computer Science 2015-12-09 Lex Fridman , Jeffrey Wildman , Steven Weber

In many biological networks the responses of individual elements are ambiguous. We consider a scenario in which many sensors respond to a shared signal, each with limited information capacity, and ask that the outputs together convey as…

Biological Physics · Physics 2025-12-30 Marianne Bauer , William Bialek

We study the capacity of a quantum channel for retrocausal communication, where messages are transmitted backward in time, from a sender in the future to a receiver in the past, through a noisy postselected closed timelike curve (P-CTC)…

Quantum Physics · Physics 2026-04-17 Kaiyuan Ji , Seth Lloyd , Mark M. Wilde

Units of complex systems -- such as neurons in the brain or individuals in societies -- must communicate efficiently to function properly: e.g., allowing electrochemical signals to travel quickly among functionally connected neuronal areas…

Physics and Society · Physics 2020-03-17 Arsham Ghavasieh , Manlio De Domenico

Biological signaling is imagined as a combination of activation and transport. The former is triggered by local molecular interactions and the latter is the result of molecular diffusion. However, other fundamental physical principles of…

Biological Physics · Physics 2016-12-07 Bernhard Fichtl , Matthias F. Schneider

A common feature of biological networks is the geometric property of self-similarity. Molecular regulatory networks through to circulatory systems, nervous systems, social systems and ecological trophic networks, show self-similar…

Molecular Networks · Quantitative Biology 2012-03-09 Simon DeDeo , David C. Krakauer

Receptor-induced apoptosis is a complex signal transduction pathway involving numerous protein/protein interactions and post-transcriptional modifications. The response to death receptor stimulation varies significantly from one cell line…

Quantitative Methods · Quantitative Biology 2017-12-20 François Bertaux , Dirk Drasdo , Gregory Batt

This paper focuses on molecular communication (MC) systems where the signaling molecules may participate in a reversible bimolecular reaction in the channel. The motivation for studying these MC systems is that they can realize the concept…

Information Theory · Computer Science 2017-11-02 Vahid Jamali , Nariman Farsad , Robert Schober , Andrea Goldsmith

The performance of communication systems is fundamentally limited by the loss of energy through propagation and circuit inefficiencies. In this article, we show that it is possible to achieve ultra low energy communications at the…

Living cells are continually exposed to environmental signals that vary in time. These signals are detected and processed by biochemical networks, which are often highly stochastic. To understand how cells cope with a fluctuating…

Molecular Networks · Quantitative Biology 2012-06-01 Wiet de Ronde , Filipe Tostevin , Pieter Rein ten Wolde

In this paper, we consider the diffusive molecular communication channel between a transmitter nano-machine and a receiver nano-machine in a fluid environment. The information molecules released by the transmitter nano-machine into the…

Emerging Technologies · Computer Science 2016-11-17 Arman Ahmadzadeh , Hamidreza Arjmanidi , Andreas Burkovski , Robert Schober

Communication between cells is realized by exchange of biochemical substances. Due to internal organization of living systems and variability of external parameters, the exchange is heavily influenced by perturbations of various parameters…

Chaotic Dynamics · Physics 2015-05-19 Dragutin T. Mihailovic , Igor Balaz

Fluctuations in the abundance of molecules in the living cell may affect its growth and well being. For regulatory molecules (e.g., signaling proteins or transcription factors), fluctuations in their expression can affect the levels of…

Molecular Networks · Quantitative Biology 2009-11-13 Erel Levine , Terence Hwa

Shortcuts in a regular architecture affect the information transport through the system due to the severe decrease in average path length. A fundamental new perspective in terms of pattern formation is the destabilizing effect of…

Statistical Mechanics · Physics 2009-11-11 Carsten Marr , Marc-Thorsten Huett

Limited feedback improves link reliability with a small amount of feedback from the receiver back to the transmitter. In cellular systems, the performance of limited feedback will be degraded in the presence of other cell interference, when…

Information Theory · Computer Science 2015-05-14 Salam Akoum , Robert W. Heath

This paper studies the problem of receiver modeling in molecular communication systems. We consider the diffusive molecular communication channel between a transmitter nano-machine and a receiver nano-machine in a fluid environment. The…

Emerging Technologies · Computer Science 2016-10-04 Arman Ahmadzadeh , Hamidreza Arjmandi , Andreas Burkovski , Robert Schober

During development, highly ordered structures emerge as cells collectively coordinate with each other. While recent advances have clarified how individual cells process and respond to external signals, understanding collective cellular…

Biological Physics · Physics 2026-02-05 Ashutosh Tripathi , Jörn Dunkel , Dominic J. Skinner

Molecular communication (MC) is a model of information transmission where the signal is transmitted by information-carrying molecules through their physical transport from a transmitter to a receiver through a communication channel. Prior…

Statistical Mechanics · Physics 2026-05-05 Phanindra Dewan , Sumantra Sarkar