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Cells are often considered input-output devices that maximize the transmission of information by converting extracellular stimuli (input) via signaling pathways (communication channel) to cell behavior (output). However, in biological…

Cell Behavior · Quantitative Biology 2019-11-04 Gabriele Micali , Robert G. Endres

In a diffusion-based molecular communication system, molecules are employed to convey information. When propagation and reception processes are considered in a framework of first passage processes, we need to focus on absorbing receivers.…

Emerging Technologies · Computer Science 2016-09-05 H. Birkan Yilmaz , Gee-Yong Suk , Chan-Byoung Chae

The ubiquity of information transmission via molecular communication between cells is comprehensively documented on Earth; this phenomenon might even have played a vital role in the origin(s) and early evolution of life. Motivated by these…

Earth and Planetary Astrophysics · Physics 2024-01-26 Manasvi Lingam

The wireless communication technologies have fundamentally revolutionized industrial operations. The operation of the automated equipment is conducted in a closed-loop manner, where the status of devices is collected and sent to the control…

Systems and Control · Electrical Eng. & Systems 2024-09-19 Zeyang Meng , Dingyou Ma , Zhiqing Wei , Ying Zhou , Zhiyong Feng

Molecular communication (MC) enables cooperation of spatially dispersed molecular robots through the feedback control mediated by diffusing signal molecules. However, conventional analysis frameworks for the MC channels mostly consider the…

Systems and Control · Electrical Eng. & Systems 2025-08-11 Taishi Kotsuka , Yutaka Hori

This paper proposes a control theoretic framework to model and analyze the self-organized pattern formation of molecular concentrations in biomolecular communication networks, emerging applications in synthetic biology. In biomolecular…

Molecular Networks · Quantitative Biology 2019-01-08 Yutaka Hori , Hiroki Miyazako , Soichiro Kumagai , Shinji Hara

Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes. We discuss how to…

Quantitative Methods · Quantitative Biology 2016-11-15 Andrew W. Eckford , Kenneth A. Loparo , Peter J. Thomas

The learning rate is an information-theoretical quantity for bipartite Markov chains describing two coupled subsystems. It is defined as the rate at which transitions in the downstream subsystem tend to increase the mutual information…

Statistical Mechanics · Physics 2017-07-04 Rory A. Brittain , Nick S. Jones , Thomas E. Ouldridge

Many biological systems dynamically rearrange their components through a sequence of configurations in order to perform their functions. Such dynamic processes have been studied using network models that sequentially retrieve a set of…

Statistical Mechanics · Physics 2022-12-01 Lukas Herron , Pablo Sartori , BingKan Xue

Composition is a powerful principle for systems biology, focused on the interfaces, interconnections, and orchestration of distributed processes to enable integrative multiscale simulations. Whereas traditional models focus on the structure…

Other Quantitative Biology · Quantitative Biology 2024-11-25 Eran Agmon

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

Neurons and Cognition · Quantitative Biology 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

This paper studies the impact of a transmitter's molecule generation process on the capacity of a concentration based Molecular Communication (MC) system. Constraints caused by the molecule generation process affect the availability of the…

Information Theory · Computer Science 2018-02-27 Hamid G. Bafghi , Amin Gohari , Mahtab Mirmohseni , Masoumeh Nasiri-Kenari

It is well-known that biological and social interaction networks have a varying degree of redundancy, though a consensus of the precise cause of this is so far lacking. In this paper, we introduce a topological redundancy measure for…

A wide variety of communication channels employ the quantized electromagnetic field to convey information. Their communication capacity crucially depends on losses associated to spatial characteristics of the channel such as diffraction and…

Quantum Physics · Physics 2012-06-21 Cosmo Lupo , Vittorio Giovannetti , Stefano Pirandola , Stefano Mancini , Seth Lloyd

Multicell joint processing can mitigate inter-cell interference and thereby increase the spectral efficiency of cellular systems. Most previous work has assumed phase-aligned (coherent) transmissions from different base transceiver stations…

Information Theory · Computer Science 2016-11-17 Mingguang Xu , Dongning Guo , Michael L. Honig

Transformers have been successfully applied to sequential, auto-regressive tasks despite being feedforward networks. Unlike recurrent neural networks, Transformers use attention to capture temporal relations while processing input tokens in…

Machine Learning · Computer Science 2021-01-26 Angela Fan , Thibaut Lavril , Edouard Grave , Armand Joulin , Sainbayar Sukhbaatar

Irreversibility, in which a transient perturbation leaves a system in a new state, is an emergent property in systems of interacting entities. This property has well-established implications in statistical physics but remains underexplored…

Molecular Networks · Quantitative Biology 2024-09-25 Yi Zhao , Thomas P. Wytock , Kimberly A. Reynolds , Adilson E. Motter

A ubiquitous way that cells share information is by exchanging molecules. Yet, the fundamental ways that this information exchange is influenced by intracellular dynamics remain unclear. Here we use information theory to investigate a…

Biological Physics · Physics 2020-07-23 Amir Erez , Tommy A. Byrd , Michael Vennettilli , Andrew Mugler

Age-of-information is a novel performance metric in communication systems to indicate the freshness of the latest received data, which has wide applications in monitoring and control scenarios. Another important performance metric in these…

Information Theory · Computer Science 2018-08-07 Jie Gong , Xiang Chen , Xiao Ma

Exchange of biochemical substances is essential way in establishing communication between bacterial cells. It is noticeable that all phases of the process are heavily influenced by perturbations of either internal or external parameters.…

Chaotic Dynamics · Physics 2010-08-18 Igor Balaz , Dragutin T. Mihailovic